{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,8,4]],"date-time":"2023-08-04T10:52:20Z","timestamp":1691146340279},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"24","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orvosi Hetilap"],"published-print":{"date-parts":[[2015,6]]},"abstract":"<jats:p> Introduction: Cardiac biomarkers have a prominent role in the diagnosis of acute myocardial infarction. Aim: The aim of the authors was to study the diagnostic effectiveness of automated measurement of cardiac biomarkers. Method: Myeloperoxidase, high-sensitivity C-reactive protein, myoglobin, heart-type fatty acid binding protein, creatine kinase, creatine kinase MB, high-sensitivity troponin I and T were measured. Results: The high-sensitivity troponin I was the most effective (area under curve: 0.86; 95% confidence interval: 0.77\u20130.95; p&lt;0.001) for the diagnosis of acute myocardial infarction. Considering a critical value of 0.35 ng\/mL, its sensitivity and specificity were 81%, and 74%, respectively. Combined evaluation of the high-sensitivity troponin T and I, chest pain, and the electrocardiogram gave the best results for separation of acute myocardial infarction from other diseases (correct classification in 62.5% and 98.9% of patients, respectively). Conclusions: Until a more sensitive and specific cardiac biomarker becomes available, the best method for the diagnosis of acute myocardial infarction is to evaluate electrocardiogram and biomarker concentration and to repeat them after 3\u20136 hours. Orv. Hetil., 2015, 156(24), 964\u2013971. <\/jats:p>","DOI":"10.1556\/650.2015.30145","type":"journal-article","created":{"date-parts":[[2015,6,8]],"date-time":"2015-06-08T08:17:26Z","timestamp":1433751446000},"page":"964-971","source":"Crossref","is-referenced-by-count":2,"title":["Automatiz\u00e1ltan m\u00e9rhet\u0151 biomarkerek az akut myocardialis                     infarctus diagnosztik\u00e1j\u00e1ban"],"prefix":"10.1556","volume":"156","author":[{"given":"Ferenc","family":"Kov\u00e1cs","sequence":"first","affiliation":[{"name":"K\u00f6zponti Laborat\u00f3rium, Kanizsai Dorottya K\u00f3rh\u00e1z Nagykanizsa, Szekeres u. 2\u20138., 8800"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ibolya","family":"Kocsis","sequence":"additional","affiliation":[{"name":"Laborat\u00f3riumi Medicina Int\u00e9zet, Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina","family":"Varga","sequence":"additional","affiliation":[{"name":"Transzplant\u00e1ci\u00f3s \u00e9s Seb\u00e9szeti Klinika,                         Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enik\u0151","family":"S\u00e1rv\u00e1ry","sequence":"additional","affiliation":[{"name":"Transzplant\u00e1ci\u00f3s \u00e9s Seb\u00e9szeti Klinika,                         Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gy\u00f6rgy","family":"Bics\u00e1k","sequence":"additional","affiliation":[{"name":"S\u00fcrg\u0151ss\u00e9gi Oszt\u00e1ly, Kanizsai Dorottya K\u00f3rh\u00e1z Nagykanizsa"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","container-title":["Orvosi Hetilap"],"original-title":[],"language":"hu","link":[{"URL":"https:\/\/www.akademiai.com\/doi\/pdf\/10.1556\/650.2015.30145","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,2,19]],"date-time":"2019-02-19T20:27:47Z","timestamp":1550608067000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.akademiai.com\/doi\/10.1556\/650.2015.30145"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6]]},"references-count":0,"journal-issue":{"issue":"24","published-print":{"date-parts":[[2015,6]]}},"alternative-id":["10.1556\/650.2015.30145"],"URL":"https:\/\/doi.org\/10.1556\/650.2015.30145","relation":{},"ISSN":["0030-6002","1788-6120"],"issn-type":[{"value":"0030-6002","type":"print"},{"value":"1788-6120","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,6]]}}}