{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T03:04:15Z","timestamp":1649127855387},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orvosi Hetilap"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:p> Anomalies of the corpus callosum are the most frequent malformations of the central nervous system. The triad of spontaneous periodic hypothermia and hyperhydrosis with the agenesis of corpus callosum is described as Shapiro syndrome. Shapiro syndrome is a very rare condition and it can occur in every age group. The presence of agenesis of corpus callosum is not a strict criteria of the syndrome; the most important presenting symptom is paroxysmal hypothermia. Although the definite cause of recurrent hypothermia is unknown, dysfunction of the hypothalamus is suspected. From therapeutic aspects, only supportive therapy is available. In this report the authors present the first Shapiro syndrome case diagnosed in Hungary. The main symptoms of the 21-year-old male patient were recurrent hyperhydrosis with hypothermia resulting in severe general malaise. The skull magnetic resonance imaging demonstrated agenesis of corpus callosum. The patient was treated with clonidine resulting in significant improvement of symptoms. Orv. Hetil., 2016, 157(7), 275\u2013278. <\/jats:p>","DOI":"10.1556\/650.2016.30369","type":"journal-article","created":{"date-parts":[[2016,2,6]],"date-time":"2016-02-06T09:18:09Z","timestamp":1454750289000},"page":"275-278","source":"Crossref","is-referenced-by-count":2,"title":["Shapiro-szindr\u00f3ma, azaz a termoregul\u00e1ci\u00f3s zavar ritka                     esete"],"prefix":"10.1556","volume":"157","author":[{"given":"J\u00falia","family":"Szab\u00f3","sequence":"first","affiliation":[{"name":"Neurol\u00f3giai Oszt\u00e1ly, J\u00e1sz-Nagykun-Szolnok Megyei Het\u00e9nyi G\u00e9za K\u00f3rh\u00e1z-Rendel\u0151int\u00e9zet Szolnok"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D\u00e9nes","family":"Z\u00e1dori","sequence":"additional","affiliation":[{"name":"Neurol\u00f3giai Klinika, Szegedi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Szent-Gy\u00f6rgyi Albert Klinikai K\u00f6zpont Szeged, Semmelweis u. 6., V. emelet, 6725"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edina T\u00edmea","family":"Varga","sequence":"additional","affiliation":[{"name":"Neurol\u00f3giai Klinika, Szegedi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Szent-Gy\u00f6rgyi Albert Klinikai K\u00f6zpont Szeged, Semmelweis u. 6., V. emelet, 6725"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00e1szl\u00f3","family":"V\u00e9csei","sequence":"additional","affiliation":[{"name":"Neurol\u00f3giai Klinika, Szegedi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Szent-Gy\u00f6rgyi Albert Klinikai K\u00f6zpont Szeged, Semmelweis u. 6., V. emelet, 6725"},{"name":"MTA\u2013SZTE Idegtudom\u00e1nyi Kutat\u00f3csoport Szeged"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","container-title":["Orvosi Hetilap"],"original-title":[],"language":"hu","link":[{"URL":"https:\/\/www.akademiai.com\/doi\/pdf\/10.1556\/650.2016.30369","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,2,19]],"date-time":"2019-02-19T19:42:57Z","timestamp":1550605377000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.akademiai.com\/doi\/10.1556\/650.2016.30369"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2]]},"references-count":0,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["10.1556\/650.2016.30369"],"URL":"https:\/\/doi.org\/10.1556\/650.2016.30369","relation":{},"ISSN":["0030-6002","1788-6120"],"issn-type":[{"value":"0030-6002","type":"print"},{"value":"1788-6120","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2]]}}}