{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T13:49:36Z","timestamp":1648993776368},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"28","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orvosi Hetilap"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:p> Introduction: Screening, prevention and treatment of familial breast cancer require a multidisciplinary approach. New guidelines were published in the United Kingdom for the management of familial breast cancer. Aim: The authors summarise these new guidelines and analyse the relevant practice in Hungary. Method: Relevant guidelines of the National Institute for Health and Care Excellence and Familial Breast Cancer Report (NHS Scotland) are described. Results: New guidelines will increase the number of genetic tests as well as genetic counselling. An increase in the number of breast magnetic resonance imaging is expected, too. Chemoprevention can be offered for individuals with medium risk and above. Promising trials are underway with platinum based chemotherapy and polyADP-ribose polimerase inhibitors for the systemic treatment of familial breast cancer. The increase in the number of genetic tests, counselling, and breast magnetic resonance imaging may have a significant impact on health care budget. Conclusions: These guidelines will change some aspects of the current management of familial breast cancer. Orv. Hetil., 2016, 157(28), 1117\u20131125. <\/jats:p>","DOI":"10.1556\/650.2016.30473","type":"journal-article","created":{"date-parts":[[2016,7,10]],"date-time":"2016-07-10T01:04:50Z","timestamp":1468112690000},"page":"1117-1125","source":"Crossref","is-referenced-by-count":0,"title":["Az \u00f6r\u00f6kletes eml\u0151r\u00e1k sz\u0171r\u00e9s\u00e9nek, megel\u0151z\u00e9s\u00e9nek \u00e9s                     kezel\u00e9s\u00e9nek \u00faj nemzetk\u00f6zi ir\u00e1nyvonalai \u2013 hazai vonatkoz\u00e1sokkal"],"prefix":"10.1556","volume":"157","author":[{"given":"L\u00e1szl\u00f3","family":"Romics","sequence":"first","affiliation":[{"name":"Department of Surgery, New Victoria Hospital \u00e9s Queen Elizabeth University Hospital Grange Road, Glasgow G42 9LF, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judit","family":"Kocsis","sequence":"additional","affiliation":[{"name":"Onkol\u00f3giai Int\u00e9zet, Debreceni Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Klinikai K\u00f6zpont Debrecen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katalin","family":"Orm\u00e1ndi","sequence":"additional","affiliation":[{"name":"Radiol\u00f3giai Klinika, Diagnoscan Magyarorsz\u00e1g Kft.,                         Szegedi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Szeged"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B\u00e9la \u00c1kos","family":"Moln\u00e1r","sequence":"additional","affiliation":[{"name":"I. Seb\u00e9szeti Klinika, Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","container-title":["Orvosi Hetilap"],"original-title":[],"language":"hu","link":[{"URL":"https:\/\/www.akademiai.com\/doi\/pdf\/10.1556\/650.2016.30473","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,2,19]],"date-time":"2019-02-19T14:58:39Z","timestamp":1550588319000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.akademiai.com\/doi\/10.1556\/650.2016.30473"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,7]]},"references-count":0,"journal-issue":{"issue":"28","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["10.1556\/650.2016.30473"],"URL":"https:\/\/doi.org\/10.1556\/650.2016.30473","relation":{},"ISSN":["0030-6002","1788-6120"],"issn-type":[{"value":"0030-6002","type":"print"},{"value":"1788-6120","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,7]]}}}