{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T05:18:42Z","timestamp":1648617522701},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"44","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orvosi Hetilap"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:p> The authors present the history of a 48-year-old woman, who developed pleural effusion, abdominal pain and ascites due to an advanced ovarian cancer. She underwent hysterectomy and bilateral adnexectomy in 2006, and histology revealed FIGO IIIB papillary adenocarcinoma. After surgery the patient recieved the standard, 6 cycle taxol-carboplatin therapy. Taxol-carboplatin therapy was reinitiated because of retroperitoneal lymph node metastases in 2008, but soon the therapy had to be changed because of progression. Thereafter the patient recieved 6 different types of chemo- and biological therapy including the off-label FOLFOX-4 treatment at seventh line. Significant regression in response to FOLFOX-4 therapy was confirmed with a progression free survival of about 9 months. The general condition of the patient was satisfying during the whole chemotherapy, and the side effects were tolerable. The overall survival was 98 months. This case history is a good example for the success of individualized, long term chemotherapy even if ovarian tumor diagnosed at advanced stage as it happened in this case. Orv. Hetil., 2016, 157(44), 1769\u20131773. <\/jats:p>","DOI":"10.1556\/650.2016.30565","type":"journal-article","created":{"date-parts":[[2016,10,30]],"date-time":"2016-10-30T01:50:50Z","timestamp":1477792250000},"page":"1769-1773","source":"Crossref","is-referenced-by-count":1,"title":["Metasztatikus ovariumcarcinoma kemoter\u00e1pi\u00e1s kezel\u00e9se                     nyolc \u00e9ven \u00e1t"],"prefix":"10.1556","volume":"157","author":[{"given":"Dorottya Katalin","family":"Horv\u00e1th","sequence":"first","affiliation":[{"name":"Onkol\u00f3giai Oszt\u00e1ly, Bajcsy-Zsilinszky K\u00f3rh\u00e1z \u00e9s Rendel\u0151int\u00e9zet Budapest, Magl\u00f3di \u00fat 89\u201391., 1106"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judit","family":"K\u00f3sa","sequence":"additional","affiliation":[{"name":"Onkol\u00f3giai Oszt\u00e1ly, Bajcsy-Zsilinszky K\u00f3rh\u00e1z \u00e9s Rendel\u0151int\u00e9zet Budapest, Magl\u00f3di \u00fat 89\u201391., 1106"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ildik\u00f3","family":"Fut\u00f3","sequence":"additional","affiliation":[{"name":"Onkol\u00f3giai Oszt\u00e1ly, Bajcsy-Zsilinszky K\u00f3rh\u00e1z \u00e9s Rendel\u0151int\u00e9zet Budapest, Magl\u00f3di \u00fat 89\u201391., 1106"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e1s","family":"Telekes","sequence":"additional","affiliation":[{"name":"Onkol\u00f3giai Oszt\u00e1ly, Bajcsy-Zsilinszky K\u00f3rh\u00e1z \u00e9s Rendel\u0151int\u00e9zet Budapest, Magl\u00f3di \u00fat 89\u201391., 1106"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","container-title":["Orvosi Hetilap"],"original-title":[],"language":"hu","link":[{"URL":"https:\/\/www.akademiai.com\/doi\/pdf\/10.1556\/650.2016.30565","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,2,19]],"date-time":"2019-02-19T14:29:25Z","timestamp":1550586565000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.akademiai.com\/doi\/10.1556\/650.2016.30565"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10]]},"references-count":0,"journal-issue":{"issue":"44","published-print":{"date-parts":[[2016,10]]}},"alternative-id":["10.1556\/650.2016.30565"],"URL":"https:\/\/doi.org\/10.1556\/650.2016.30565","relation":{},"ISSN":["0030-6002","1788-6120"],"issn-type":[{"value":"0030-6002","type":"print"},{"value":"1788-6120","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10]]}}}