{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T09:41:36Z","timestamp":1648892496261},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orvosi Hetilap"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:p> Abstract: <\/jats:p><jats:p> Hydrochlorothiazide became one of the most commonly prescribed first-line antihypertensive medication, though its use is often complicated with serious side-effects. A 66-year-old female patient with a history of hypertension had suffered a transient loss of consciousness, and referred to our cardiology unit with an ST-segment elevation and giant negative T-waves in V1-2 ECG leads, long QT-segment and elevated serum creatine-kinase (5392 U\/L) and troponin I (4,357 ng\/ml) levels. Acute myocardial infarction was not proven (later coronarography revealed preserved coronary circulation), but severe hyponatraemia and hypokalaemia was detected, explaining a possible symptomatic seizure, and which could be accounted for a 25 mg daily hydrochlorothiazide antihypertensive treatment and \u2013 as a precipitating insult \u2013 a one-week history of gastroenteritis. The case-report presents a unique differential diagnostic question where thiazide-induced hyponatraemia and hypokalaemia resulted in a clinical picture sharing some similarities with acute myocardial infarction. This case underlines the serious side-effects of an inappropriately used common antihypertensive medication. Orv. Hetil., 2017, 158(11), 426\u2013431. <\/jats:p>","DOI":"10.1556\/650.2017.30624","type":"journal-article","created":{"date-parts":[[2017,3,13]],"date-time":"2017-03-13T12:53:13Z","timestamp":1489409593000},"page":"426-431","source":"Crossref","is-referenced-by-count":1,"title":["Az \u00fcgyeleti ell\u00e1t\u00e1s \u00fatveszt\u0151i egy korszer\u0171tlen                     k\u00e9sz\u00edtm\u00e9ny okozta iatrogenia kapcs\u00e1n"],"prefix":"10.1556","volume":"158","author":[{"given":"P\u00e9ter","family":"Ar\u00e1nyi","sequence":"first","affiliation":[{"name":"Kardiol\u00f3giai Oszt\u00e1ly, Budai Irgalmasrendi K\u00f3rh\u00e1z Budapest, \u00c1rp\u00e1d fejedelem \u00fatja 7., 1023"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00e1nos","family":"Tomcs\u00e1nyi","sequence":"additional","affiliation":[{"name":"Kardiol\u00f3giai Oszt\u00e1ly, Budai Irgalmasrendi K\u00f3rh\u00e1z Budapest, \u00c1rp\u00e1d fejedelem \u00fatja 7., 1023"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","container-title":["Orvosi Hetilap"],"original-title":[],"language":"hu","link":[{"URL":"https:\/\/www.akademiai.com\/doi\/pdf\/10.1556\/650.2017.30624","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,2,19]],"date-time":"2019-02-19T20:05:47Z","timestamp":1550606747000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.akademiai.com\/doi\/10.1556\/650.2017.30624"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3]]},"references-count":0,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["10.1556\/650.2017.30624"],"URL":"https:\/\/doi.org\/10.1556\/650.2017.30624","relation":{},"ISSN":["0030-6002","1788-6120"],"issn-type":[{"value":"0030-6002","type":"print"},{"value":"1788-6120","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3]]}}}