{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T08:34:53Z","timestamp":1648542893035},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"Supplement 1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orvosi Hetilap"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:p> Diagnosis and treatment of HBV\/HDV infection means for the patient to be able to maintain working capacity, to increase quality of life, to prevent cancer, and to prolong life expectancy, while society benefits from eliminating the chances of further transmission of the viruses, and decreasing the overall costs of serious complications. The guideline delineates the treatment algorithms for 2017 set by a consensus meeting of physicians involved in the treatment of these diseases. The prevalence of HBV infection in the Hungarian general population is 0.5\u20130.7%. The indications of treatment is based upon viral examinations (including viral nucleic acid determination), determinations of disease activity and stage (including biochemical, pathologic, and\/or non-invasive methods), and excluding contraindications. To avoid unnecessary side effects and for cost-effective approach the guideline stresses the importance of quick and detailed virologic evaluations, the applicability of elastography as an acceptable alternative of liver biopsy in this regard, as well as the relevance of appropriate consistent follow up schedule for viral response during therapy. The first choice of therapy in chronic hepatitis B infection can be pegylated interferon for 48 weeks or continuous entecavir or tenofovir therapy. The latter two must be continued for at least 12 months after hepatitis B surface antigen seroconversion. Adefovir dipivoxil is recommended mainly in combination therapy. Lamivudine is no longer a first choice; patients currently taking lamivudine must switch if response is inadequate. Appropriate treatment of patients taking immunosuppressive medications is highly recommended. Pegylated interferon based therapy is recommended for the treatment of concomitant hepatitis D infection. Orv. Hetil., 2017, 158(Suppl. 1) 23\u201335. <\/jats:p>","DOI":"10.1556\/650.2017.30689","type":"journal-article","created":{"date-parts":[[2017,2,21]],"date-time":"2017-02-21T14:20:43Z","timestamp":1487686843000},"page":"23-35","source":"Crossref","is-referenced-by-count":0,"title":["A hepatitis B- \u00e9s D-v\u00edrus-fert\u0151z\u00e9s diagnosztik\u00e1ja,                     antivir\u00e1lis kezel\u00e9se. <i>Magyar konszenzusaj\u00e1nl\u00e1s. \u00c9rv\u00e9nyes: 2016. okt\u00f3ber                         15-t\u0151l<\/i>"],"prefix":"10.1556","volume":"158","author":[{"given":"G\u00e1bor","family":"Horv\u00e1th","sequence":"first","affiliation":[{"name":"Budai Hepatol\u00f3giai Centrum, Szent J\u00e1nos K\u00f3rh\u00e1z \u00e9s \u00c9szak-budai Egyes\u00edtett K\u00f3rh\u00e1zak, Hepatol\u00f3giai Szakambulancia, Budapest, Egry J\u00f3zsef u 1\u20133., 1111"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zsuzsanna","family":"Gerlei","sequence":"additional","affiliation":[{"name":"Transzplant\u00e1ci\u00f3s \u00e9s Seb\u00e9szeti Klinika,                         Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judit","family":"Gervain","sequence":"additional","affiliation":[{"name":"I. 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Belgy\u00f3gy\u00e1szati Klinika, Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Istv\u00e1n","family":"Tornai","sequence":"additional","affiliation":[{"name":"Orvos- \u00e9s Eg\u00e9szs\u00e9gtudom\u00e1nyi Centrum, Belgy\u00f3gy\u00e1szati                     Int\u00e9zet, Debreceni Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Debrecen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kl\u00e1ra","family":"Werling","sequence":"additional","affiliation":[{"name":"II. Belgy\u00f3gy\u00e1szati Klinika, Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B\u00e9la","family":"Hunyady","sequence":"additional","affiliation":[{"name":"I. 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