{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T02:10:20Z","timestamp":1649038220014},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"20","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orvosi Hetilap"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:p> Abstract: <\/jats:p><jats:p> Gastroesophageal reflux disease affects more than 10% of the adult population. Most patients can be effectively treated with lifestyle changes and adequate acid-reducing therapy. However, about 10% of the patients remain symptomatic despite treatment and severe complications may develop. Interestingly, some of these complications seem to be a sort of defensive mechanism that may either alleviate the patient\u2019s symptoms or prevent developing further complications. In Barrett\u2019s esophagus, which can be unambigously considered as a complication of gastroesophageal reflux disease, reflux symptoms ruining the quality of life may significantly improve, since the metaplastic Barrett epithelium is much more resistent to gastric acid, than the normal epithelial lining of the esophagus. Furthermore, the motility disorders (hypertensive lower esophageal sphincter, achalasia, cricopharyngeal achalasia) and structural changes (Schatzki\u2019s ring, esophageal stricture, subglottic trachea stenosis), which develop as a complication of reflux may help to prevent aspiration that can cause new complaints and may lead to further complications. Orv Hetil. 2017; 158(20): 763\u2013769. <\/jats:p>","DOI":"10.1556\/650.2017.30759","type":"journal-article","created":{"date-parts":[[2017,5,15]],"date-time":"2017-05-15T08:52:41Z","timestamp":1494838361000},"page":"763-769","source":"Crossref","is-referenced-by-count":0,"title":["A gastrooesophagealis refluxbetegs\u00e9g                     nyel\u0151cs\u0151sz\u00f6v\u0151dm\u00e9nyei: k\u00f6vetkezm\u00e9nyek vagy v\u00e9dekez\u0151reakci\u00f3k?"],"prefix":"10.1556","volume":"158","author":[{"given":"\u00d6rs P\u00e9ter","family":"Horv\u00e1th","sequence":"first","affiliation":[{"name":"Klinikai K\u00f6zpont, Seb\u00e9szeti Klinika, P\u00e9csi Tudom\u00e1nyegyetem P\u00e9cs, Ifj\u00fas\u00e1g \u00fatja 13., 7624"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"Bogn\u00e1r","sequence":"additional","affiliation":[{"name":"Seb\u00e9szeti Oktat\u00f3 \u00e9s Kutat\u00f3 Int\u00e9zet, P\u00e9csi Tudom\u00e1nyegyetem P\u00e9cs"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e1s","family":"Papp","sequence":"additional","affiliation":[{"name":"Klinikai K\u00f6zpont, Seb\u00e9szeti Klinika, P\u00e9csi Tudom\u00e1nyegyetem P\u00e9cs, Ifj\u00fas\u00e1g \u00fatja 13., 7624"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e1s","family":"Vereczkei","sequence":"additional","affiliation":[{"name":"Klinikai K\u00f6zpont, Seb\u00e9szeti Klinika, P\u00e9csi Tudom\u00e1nyegyetem P\u00e9cs, Ifj\u00fas\u00e1g \u00fatja 13., 7624"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","container-title":["Orvosi Hetilap"],"original-title":[],"language":"hu","link":[{"URL":"https:\/\/www.akademiai.com\/doi\/pdf\/10.1556\/650.2017.30759","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,2,19]],"date-time":"2019-02-19T20:09:20Z","timestamp":1550606960000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.akademiai.com\/doi\/10.1556\/650.2017.30759"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5]]},"references-count":0,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["10.1556\/650.2017.30759"],"URL":"https:\/\/doi.org\/10.1556\/650.2017.30759","relation":{},"ISSN":["0030-6002","1788-6120"],"issn-type":[{"value":"0030-6002","type":"print"},{"value":"1788-6120","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5]]}}}