{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T18:41:29Z","timestamp":1785782489688,"version":"3.56.0"},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"27","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orvosi Hetilap"],"published-print":{"date-parts":[[2017,7]]},"abstract":" Abstract: <\/jats:p> Introduction and aim: The aim was to study the patients\u2019 adherence to some evidence-based medication (statins, beta blockers, platelet and RAS inhibitors) after suffering a myocardial infarction, and its impact on the outcome. Method: Retrospective observational cohort study was carried out from the data of the Hungarian Myocardial Infarction Registry between January 1, 2013, and December 31, 2014. 14,843 patients were alive at the end of hospital treatment, from them, those who had no myocardial infarction or death until 180 days were followed for one year. The adherence was defined as the proportion of time from the index event to the endpoint (or censoring) covered with prescription fillings. The endpoint was defined as death or reinfarction. Information on filling prescriptions for statins, platelet aggregation inhibitors, beta blockers and ARB\/ACEI-inhibitors were obtained. Multivariate regression was used to model adherence and survival time. Results: Good adherence (\\>80%) to clopidogrel, statins, beta blockers, aspirin and ARB\/ACEI was found in 64.9%, 54.4%, 36.5%, 31.7% and 64.0%, respectively. Patients treated with PCI during the index hospitalization had higher adherence to all medication (all p<0.01), except for beta-blocker (p = 0.484). Multivariate analysis confirmed that adherence to statins, to clopidogrel and ARB\/ACEI-inhibitors was associated with 10.1% (p<0.0001), 10.4% (p = 0.0002) and 15.8% (p<0.0001) lower hazard of endpoint respectively for 25% points increase in adherence, controlling for age, sex, performing of PCI, 5 anamnestic data and date of index event. Adherence to aspirin and beta blockers was not significantly associated with the hazard. Conclusion: Higher adherence to some evidence-based medications was found to be associated with improved long term prognosis of the patients. Orv Hetil. 2017; 158(27): 1051\u20131057. <\/jats:p>","DOI":"10.1556\/650.2017.30795","type":"journal-article","created":{"date-parts":[[2017,7,3]],"date-time":"2017-07-03T09:37:40Z","timestamp":1499074660000},"page":"1051-1057","source":"Crossref","is-referenced-by-count":8,"title":["Sz\u00edvinfarktust t\u00fal\u00e9lt betegek ter\u00e1piah\u0171s\u00e9ge a m\u00e1sodlagos megel\u0151z\u00e9s szempontj\u00e1b\u00f3l fontos gy\u00f3gyszeres kezel\u00e9sekhez"],"prefix":"10.1556","volume":"158","author":[{"given":"Andr\u00e1s","family":"J\u00e1nosi","sequence":"first","affiliation":[{"name":"Gottsegen Gy\u00f6rgy Orsz\u00e1gos Kardiol\u00f3giai Int\u00e9zet Budapest, Haller utca 29., 1096"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u00e9ter","family":"Ofner","sequence":"additional","affiliation":[{"name":"Gottsegen Gy\u00f6rgy Orsz\u00e1gos Kardiol\u00f3giai Int\u00e9zet Budapest, Haller utca 29., 1096"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zolt\u00e1n","family":"Kiss","sequence":"additional","affiliation":[{"name":"II. Belgy\u00f3gy\u00e1szati Klinika \u00e9s Nefrol\u00f3giai K\u00f6zpont, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar P\u00e9cs"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Levente","family":"Kiss","sequence":"additional","affiliation":[{"name":"Kazincbarcikai K\u00f3rh\u00e1z Nonprofit Kft. Kazincbarcika"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R\u00f3bert G\u00e1bor","family":"Kiss","sequence":"additional","affiliation":[{"name":"Honv\u00e9dk\u00f3rh\u00e1z, Magyar Honv\u00e9ds\u00e9g Eg\u00e9szs\u00e9g\u00fcgyi K\u00f6zpont Budapest"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f3zsef","family":"Dinny\u00e9s","sequence":"additional","affiliation":[{"name":"Vaszary Kolos K\u00f3rh\u00e1z Esztergom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zolt\u00e1n","family":"J\u00e1rai","sequence":"additional","affiliation":[{"name":"Szent Imre Egyetemi Oktat\u00f3k\u00f3rh\u00e1z Budapest"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gergely","family":"Nagy","sequence":"additional","affiliation":[{"name":"Egyetemi Oktat\u00f3k\u00f3rh\u00e1z, Borsod-Aba\u00faj-Zempl\u00e9n Megyei K\u00f3rh\u00e1z Miskolc"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00e1bor","family":"Veress","sequence":"additional","affiliation":[{"name":"\u00c1llami Sz\u00edvk\u00f3rh\u00e1z Balatonf\u00fcred"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tam\u00e1s","family":"Ferenci","sequence":"additional","affiliation":[{"name":"Neumann J\u00e1nos Informatikai Tansz\u00e9k, \u00c9lettani Szab\u00e1lyoz\u00e1sok Csoport, \u00d3budai Egyetem Budapest"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","container-title":["Orvosi Hetilap"],"original-title":[],"language":"hu","link":[{"URL":"https:\/\/www.akademiai.com\/doi\/pdf\/10.1556\/650.2017.30795","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,2,19]],"date-time":"2019-02-19T20:12:23Z","timestamp":1550607143000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.akademiai.com\/doi\/10.1556\/650.2017.30795"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7]]},"references-count":0,"journal-issue":{"issue":"27","published-print":{"date-parts":[[2017,7]]}},"alternative-id":["10.1556\/650.2017.30795"],"URL":"https:\/\/doi.org\/10.1556\/650.2017.30795","relation":{},"ISSN":["0030-6002","1788-6120"],"issn-type":[{"value":"0030-6002","type":"print"},{"value":"1788-6120","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,7]]}}}