{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,31]],"date-time":"2022-03-31T01:56:20Z","timestamp":1648691780224},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"33","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orvosi Hetilap"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:p> Abstract: <\/jats:p><jats:p> Introduction: In their previous works, the authors reported findings from familial hematologic malignancies in Szabolcs-Szatm\u00e1r-Bereg county, Hungary. So far there are no other studies on this topic available in Hungary. Aim: Detailed analysis of epidemiologic features of hematologic malignancies of siblings. Method: During a 34-year period (between January 1, 1983 and December 31, 2016), 86 families with hematologic malignancies were recorded in Szabolcs-Szatm\u00e1r-Bereg county. Among them, 19 cases of the affected siblings were registered. Results: In one family there were three sisters with polycythaemia vera, hence the number of analysed disease associations was 21. In all of the 21 cases, the younger sibling\u2019s disease developed earlier. The average anteposition was 10.8 (1\u201333) years (median: 10 years). Conclusion: The anticipation was earlier observed in multigeneration hematological malignancies between direct and collateral descendants. On the basis of the above data, anteposition of the disease was observed in younger siblings. Orv Hetil. 2017; 158(33): 1283\u20131287. <\/jats:p>","DOI":"10.1556\/650.2017.30830","type":"journal-article","created":{"date-parts":[[2017,8,14]],"date-time":"2017-08-14T12:00:23Z","timestamp":1502712023000},"page":"1283-1287","source":"Crossref","is-referenced-by-count":0,"title":["Antepoz\u00edci\u00f3 testv\u00e9rekben \u00e9szlelt malignus hematol\u00f3giai                     betegs\u00e9gekben. <i>A 34 \u00e9ves Szabolcs-Szatm\u00e1r-Bereg megyei                         leukaemia\/lymphoma regiszter adataib\u00f3l levonhat\u00f3                     k\u00f6vetkeztet\u00e9sek<\/i>"],"prefix":"10.1556","volume":"158","author":[{"given":"J\u00e1nos","family":"Jak\u00f3","sequence":"first","affiliation":[{"name":"Hematol\u00f3giai Oszt\u00e1ly, Szabolcs-Szatm\u00e1r-Bereg Megyei J\u00f3sa Andr\u00e1s Oktat\u00f3k\u00f3rh\u00e1z Ny\u00edregyh\u00e1za, Luk\u00e1cs \u00d6d\u00f6n utca 4., 4400"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00e1szl\u00f3","family":"Szerafin","sequence":"additional","affiliation":[{"name":"Hematol\u00f3giai Oszt\u00e1ly, Szabolcs-Szatm\u00e1r-Bereg Megyei J\u00f3sa Andr\u00e1s Oktat\u00f3k\u00f3rh\u00e1z Ny\u00edregyh\u00e1za, Luk\u00e1cs \u00d6d\u00f6n utca 4., 4400"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","container-title":["Orvosi Hetilap"],"original-title":[],"language":"hu","link":[{"URL":"https:\/\/www.akademiai.com\/doi\/pdf\/10.1556\/650.2017.30830","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,2,19]],"date-time":"2019-02-19T14:41:51Z","timestamp":1550587311000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.akademiai.com\/doi\/10.1556\/650.2017.30830"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8]]},"references-count":0,"journal-issue":{"issue":"33","published-print":{"date-parts":[[2017,8]]}},"alternative-id":["10.1556\/650.2017.30830"],"URL":"https:\/\/doi.org\/10.1556\/650.2017.30830","relation":{},"ISSN":["0030-6002","1788-6120"],"issn-type":[{"value":"0030-6002","type":"print"},{"value":"1788-6120","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8]]}}}