{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T20:09:34Z","timestamp":1649189374270},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orvosi Hetilap"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:p> Abstract: <\/jats:p><jats:p> Authors report on a case of a male patient of systemic mastocytosis that was associated with extensive cutaneous lesions. Chronic diarrhoea worsening his quality of life was well managed by the administration of antihistamines. The pleural fluid recurrence soon after drainage has been controlled by the administration of alpha interferon. 40 years after the onset of the first skin signs progression has been manifested in the development of \u201cB\u201d (bone marrow infiltration rate &gt;30%, dysmyelopoiesis, serum tryptase &gt;20 \u03bcg\/L, hepato- and splenomegaly) and \u201cC\u201d symptoms (liver function test abnormalities, cytopenia, malabsorption, osteoporosis). The patient died at age of 87. The authors\u2019 aim was to attract attention on this rare disease and emphasize that symptomatic therapy with antihistamines and drugs available based on customised rights by the National Health Insurance Fund might provide good quality of life. Orv Hetil. 2018; 159(5): 192\u2013196. <\/jats:p>","DOI":"10.1556\/650.2018.30978","type":"journal-article","created":{"date-parts":[[2018,1,29]],"date-time":"2018-01-29T02:32:59Z","timestamp":1517193179000},"page":"192-196","source":"Crossref","is-referenced-by-count":0,"title":["Progressz\u00edv k\u00f3rlefoly\u00e1st mutat\u00f3 sziszt\u00e9m\u00e1s                     mastocytosis"],"prefix":"10.1556","volume":"159","author":[{"given":"Judit","family":"V\u00e1rkonyi","sequence":"first","affiliation":[{"name":"III. Belgy\u00f3gy\u00e1szati Klinika, Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Budapest, K\u00fatv\u00f6lgyi \u00fat 4., 1125"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gergely","family":"Szombath","sequence":"additional","affiliation":[{"name":"III. Belgy\u00f3gy\u00e1szati Klinika, Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Budapest, K\u00fatv\u00f6lgyi \u00fat 4., 1125"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"V\u00e1lyi-Nagy","sequence":"additional","affiliation":[{"name":"III. Belgy\u00f3gy\u00e1szati Klinika, Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Budapest, K\u00fatv\u00f6lgyi \u00fat 4., 1125"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judit","family":"Csomor","sequence":"additional","affiliation":[{"name":"I. Patol\u00f3giai Int\u00e9zet, Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krisztina","family":"Egedi","sequence":"additional","affiliation":[{"name":"I. 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