{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,9]],"date-time":"2024-08-09T09:08:50Z","timestamp":1723194530307},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"Supplement 1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orvosi Hetilap"],"published-print":{"date-parts":[[2018,2]]},"abstract":"<jats:p> Diagnosis and treatment of hepatitis B virus (HBV) and hepatitis D virus infection mean for the patient to be able to maintain working capacity, to increase quality of life, to prevent cancer, and to prolong life expectancy, while the society benefits from eliminating the chances of further transmission of the viruses, and decreasing the overall costs of serious complications. The guideline delineates the treatment algorithms from 22 September 2017 set by a consensus meeting of physicians involved in the treatment of these diseases. The prevalence of HBV infection in the Hungarian general population is 0,5\u20130,7%. The indications of treatment are based upon viral examinations (including viral nucleic acid determination), determinations of disease activity and stage (including biochemical, pathologic, and\/or non-invasive methods), and excluding contraindications. To avoid unnecessary side effects and for a cost-effective approach, the guideline stresses the importance of quick and detailed virologic evaluations, the applicability of transient elastography as an acceptable alternative of liver biopsy in this regard as well as the relevance of appropriate consistent follow-up schedule for viral response during therapy. The first choice of therapy in chronic HBV infection can be pegylated interferon for 48 weeks or continuous entecavir or tenofovir therapy. The latter two must be continued for at least 12 months after hepatitis B surface antigen seroconversion. Lamivudine is no longer the first choice; patients currently taking lamivudine must switch if the response is inadequate. Appropriate treatment of patients taking immunosuppressive medications is highly recommended. Pegylated interferon based therapy is recommended for the treatment of concomitant hepatitis D infection. Orv Hetil. 2018; 159(Suppl 1): 24\u201337. <\/jats:p>","DOI":"10.1556\/650.2018.31004","type":"journal-article","created":{"date-parts":[[2018,2,24]],"date-time":"2018-02-24T09:00:14Z","timestamp":1519462814000},"page":"24-37","source":"Crossref","is-referenced-by-count":4,"title":["A hepatitis B- \u00e9s D-v\u00edrus-fert\u0151z\u00e9s diagnosztik\u00e1ja,                     antivir\u00e1lis kezel\u00e9se. <i>Magyar konszenzusaj\u00e1nl\u00e1s. \u00c9rv\u00e9nyes: 2017.                         szeptember 22-t\u0151l<\/i>"],"prefix":"10.1556","volume":"159","author":[{"given":"G\u00e1bor","family":"Horv\u00e1th","sequence":"first","affiliation":[{"name":"Hepatol\u00f3giai Szakrendel\u00e9s Budapest \u00e9s Budai Hepatol\u00f3giai                     Centrum, Szent J\u00e1nos K\u00f3rh\u00e1z \u00e9s \u00c9szak-budai Egyes\u00edtett K\u00f3rh\u00e1zak Budapest, Egry J\u00f3zsef u. 1\u20133., 1111"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zsuzsanna","family":"Gerlei","sequence":"additional","affiliation":[{"name":"Transzplant\u00e1ci\u00f3s \u00e9s Seb\u00e9szeti Klinika,                         Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judit","family":"Gervain","sequence":"additional","affiliation":[{"name":"I. Belgy\u00f3gy\u00e1szat \u00e9s Molekul\u00e1ris Diagnosztikai                     Laborat\u00f3rium, Szent Gy\u00f6rgy Egyetemi Oktat\u00f3 K\u00f3rh\u00e1z Sz\u00e9kesfeh\u00e9rv\u00e1r"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriella","family":"Lengyel","sequence":"additional","affiliation":[{"name":"II. Belgy\u00f3gy\u00e1szati Klinika, Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mih\u00e1ly","family":"Makara","sequence":"additional","affiliation":[{"name":"Egyes\u00edtett Szent Istv\u00e1n \u00e9s Szent L\u00e1szl\u00f3 K\u00f3rh\u00e1z Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alajos","family":"P\u00e1r","sequence":"additional","affiliation":[{"name":"I. 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Belgy\u00f3gy\u00e1szati Klinika, Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Istv\u00e1n","family":"Tornai","sequence":"additional","affiliation":[{"name":"Orvos- \u00e9s Eg\u00e9szs\u00e9gtudom\u00e1nyi Centrum, Belgy\u00f3gy\u00e1szati                     Int\u00e9zet, Debreceni Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Debrecen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kl\u00e1ra","family":"Werling","sequence":"additional","affiliation":[{"name":"II. Belgy\u00f3gy\u00e1szati Klinika, Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B\u00e9la","family":"Hunyady","sequence":"additional","affiliation":[{"name":"I. Belgy\u00f3gy\u00e1szati Klinika, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar P\u00e9cs"},{"name":"Gasztroenterol\u00f3giai Oszt\u00e1ly, Somogy Megyei Kaposi M\u00f3r Oktat\u00f3 K\u00f3rh\u00e1z Kaposv\u00e1r"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","container-title":["Orvosi Hetilap"],"original-title":[],"language":"hu","link":[{"URL":"https:\/\/www.akademiai.com\/doi\/pdf\/10.1556\/650.2018.31004","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,9]],"date-time":"2020-01-09T10:42:01Z","timestamp":1578566521000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.akademiai.com\/doi\/10.1556\/650.2018.31004"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2]]},"references-count":0,"journal-issue":{"issue":"Supplement 1","published-print":{"date-parts":[[2018,2]]}},"alternative-id":["10.1556\/650.2018.31004"],"URL":"https:\/\/doi.org\/10.1556\/650.2018.31004","relation":{},"ISSN":["0030-6002","1788-6120"],"issn-type":[{"value":"0030-6002","type":"print"},{"value":"1788-6120","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,2]]}}}