{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T23:37:40Z","timestamp":1692661060958},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orvosi Hetilap"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:p> Abstract: <\/jats:p><jats:p> Wegener\u2019s granulomatosis \u2013 or, in other words, granulomatosis with polyangiitis \u2013 is an anti-neutrophil cytoplasmic antibody associated granuloma forming vasculitis, mainly affecting the respiratory tract and the renal system. Otologic manifestations of Wegener\u2019s disease can be otitis media with effusion or chronic silent mastoiditis with conductive hearing loss, but sensorineural hearing loss can also evolve. The diagnosis is based on the clinical appearance as well as the immunoserological and histopathological results. It is of paramount importance to begin a combined immunosuppressive treatment immediately, besides eradicating the otologic manifestations. The intractable cases of chronic otitis media due to Wegener\u2019s granulomatosis are challenging any ear surgeons. Subtotal petrosectomy has proved to be an effective solution in such cases to create a dry ear and to provide a safe surgical field for hearing restoration. The authors reviewed the literature and report a case history to present the modern management of Wegener\u2019s granulomatosis with otologic manifestation. Orv Hetil. 2019; 160(4): 151\u2013157. <\/jats:p>","DOI":"10.1556\/650.2018.31266","type":"journal-article","created":{"date-parts":[[2019,1,20]],"date-time":"2019-01-20T08:17:35Z","timestamp":1547972255000},"page":"151-157","source":"Crossref","is-referenced-by-count":1,"title":["Wegener-granulomatosis talaj\u00e1n kialakult kr\u00f3nikus                     gennyes k\u00f6z\u00e9pf\u00fclgyullad\u00e1s komplex kezel\u00e9se"],"prefix":"10.1556","volume":"160","author":[{"given":"Istv\u00e1n","family":"T\u00f3th","sequence":"first","affiliation":[{"name":"Klinikai K\u00f6zpont, F\u00fcl-Orr-G\u00e9g\u00e9szeti \u00e9s Fej-Nyakseb\u00e9szeti                     Klinika, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar P\u00e9cs, Munk\u00e1csy M. u. 2., 7621"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B\u00e1lint","family":"Kasz\u00e1s","sequence":"additional","affiliation":[{"name":"Klinikai K\u00f6zpont, Pathologiai Int\u00e9zet,                         P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar P\u00e9cs"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00e1bor","family":"Horv\u00e1th","sequence":"additional","affiliation":[{"name":"Klinikai K\u00f6zpont, Reumatol\u00f3giai \u00e9s Immunol\u00f3giai Klinika,                         P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar P\u00e9cs"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zal\u00e1n","family":"Piski","sequence":"additional","affiliation":[{"name":"Klinikai K\u00f6zpont, F\u00fcl-Orr-G\u00e9g\u00e9szeti \u00e9s Fej-Nyakseb\u00e9szeti                     Klinika, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar P\u00e9cs, Munk\u00e1csy M. u. 2., 7621"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P\u00e9ter","family":"Bak\u00f3","sequence":"additional","affiliation":[{"name":"Klinikai K\u00f6zpont, F\u00fcl-Orr-G\u00e9g\u00e9szeti \u00e9s Fej-Nyakseb\u00e9szeti                     Klinika, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar P\u00e9cs, Munk\u00e1csy M. u. 2., 7621"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00e1szl\u00f3","family":"Lujber","sequence":"additional","affiliation":[{"name":"Klinikai K\u00f6zpont, F\u00fcl-Orr-G\u00e9g\u00e9szeti \u00e9s Fej-Nyakseb\u00e9szeti                     Klinika, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar P\u00e9cs, Munk\u00e1csy M. u. 2., 7621"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Imre","family":"Gerlinger","sequence":"additional","affiliation":[{"name":"Klinikai K\u00f6zpont, F\u00fcl-Orr-G\u00e9g\u00e9szeti \u00e9s Fej-Nyakseb\u00e9szeti                     Klinika, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar P\u00e9cs, Munk\u00e1csy M. u. 2., 7621"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P\u00e9ter","family":"R\u00e9v\u00e9sz","sequence":"additional","affiliation":[{"name":"Klinikai K\u00f6zpont, F\u00fcl-Orr-G\u00e9g\u00e9szeti \u00e9s Fej-Nyakseb\u00e9szeti                     Klinika, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar P\u00e9cs, Munk\u00e1csy M. u. 2., 7621"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","container-title":["Orvosi Hetilap"],"original-title":[],"language":"hu","link":[{"URL":"https:\/\/www.akademiai.com\/doi\/pdf\/10.1556\/650.2018.31266","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,11]],"date-time":"2019-04-11T06:04:16Z","timestamp":1554962656000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.akademiai.com\/doi\/10.1556\/650.2018.31266"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["10.1556\/650.2018.31266"],"URL":"https:\/\/doi.org\/10.1556\/650.2018.31266","relation":{},"ISSN":["0030-6002","1788-6120"],"issn-type":[{"value":"0030-6002","type":"print"},{"value":"1788-6120","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1]]}}}