{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,20]],"date-time":"2024-09-20T16:30:32Z","timestamp":1726849832598},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orvosi Hetilap"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:p> Abstract: <\/jats:p><jats:p> Cardiovascular disease is recognized as the leading cause of death and disability in the world. The majority of these deaths can be attributed to atherosclerotic disease and thromboembolic events leading to ischemic heart disease and stroke. The role of inflammation is well recognized in the pathogenesis of atherosclerosis and atherothrombosis. Increasing number of studies support the hypothesis that periodontal disease, specifically periodontitis, is a potential risk factor for atherosclerosis and thus cardiovascular disease. Chronic infections of periodontal pockets act as reservoirs for pathogenic microorganisms, their toxins and degradation products, raising the overall systemic inflammatory burden. Entering the circulation and atherosclerotic lesions themselves, they lead to further local and systemic inflammatory response, in all contributing to atherosclerosis progression, potentially increasing cardiovascular risk. Along these lines, good oral health in general and the periodontal treatment in more severe cases may play a role in cardiovascular risk reduction, primary and secondary prevention. The present review summarizes the possible pathophysiological mechanisms linking periodontal and cardiovascular pathology, lists clinical evidence between periodontitis and specific forms of cardiovascular disease and looks forward at the potential role of periodontal treatment in cardiovascular disease prevention and treatment. Orv Hetil. 2019; 160(11): 419\u2013425. <\/jats:p>","DOI":"10.1556\/650.2019.31301","type":"journal-article","created":{"date-parts":[[2019,3,11]],"date-time":"2019-03-11T03:13:44Z","timestamp":1552274024000},"page":"419-425","source":"Crossref","is-referenced-by-count":9,"title":["A fog\u00e1gybetegs\u00e9g mint az atheroscleroticus                     cardiovascularis betegs\u00e9g rizik\u00f3faktora"],"prefix":"10.1556","volume":"160","author":[{"given":"Dorottya","family":"Gheorghita","sequence":"first","affiliation":[{"name":"Konzerv\u00e1l\u00f3 \u00e9s Eszt\u00e9tikai Fog\u00e1szati Tansz\u00e9k,                         Szegedi Tudom\u00e1nyegyetem, Fogorvostudom\u00e1nyi Kar Szeged, Tisza Lajos k\u00f6r\u00fat 64\u201366., 6720"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriella","family":"E\u00f6rdegh","sequence":"additional","affiliation":[{"name":"Konzerv\u00e1l\u00f3 \u00e9s Eszt\u00e9tikai Fog\u00e1szati Tansz\u00e9k,                         Szegedi Tudom\u00e1nyegyetem, Fogorvostudom\u00e1nyi Kar Szeged, Tisza Lajos k\u00f6r\u00fat 64\u201366., 6720"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferenc","family":"Nagy","sequence":"additional","affiliation":[{"name":"II. Belgy\u00f3gy\u00e1szati Klinika \u00e9s Kardiol\u00f3giai K\u00f6zpont,                     Invaz\u00edv Kardiol\u00f3giai R\u00e9szleg, Szegedi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Szeged"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1rk","family":"Antal","sequence":"additional","affiliation":[{"name":"Konzerv\u00e1l\u00f3 \u00e9s Eszt\u00e9tikai Fog\u00e1szati Tansz\u00e9k,                         Szegedi Tudom\u00e1nyegyetem, Fogorvostudom\u00e1nyi Kar Szeged, Tisza Lajos k\u00f6r\u00fat 64\u201366., 6720"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","container-title":["Orvosi Hetilap"],"original-title":[],"language":"hu","link":[{"URL":"https:\/\/www.akademiai.com\/doi\/pdf\/10.1556\/650.2019.31301","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,3,31]],"date-time":"2019-03-31T02:46:33Z","timestamp":1554000393000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.akademiai.com\/doi\/10.1556\/650.2019.31301"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3]]},"references-count":0,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["10.1556\/650.2019.31301"],"URL":"https:\/\/doi.org\/10.1556\/650.2019.31301","relation":{},"ISSN":["0030-6002","1788-6120"],"issn-type":[{"value":"0030-6002","type":"print"},{"value":"1788-6120","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3]]}}}