{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T08:26:38Z","timestamp":1759479998765},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"14","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orvosi Hetilap"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:p> Abstract: <\/jats:p><jats:p> Introduction and aim: To assess the prevalence of lactase gene promoter C\/T<jats:sub>13910<\/jats:sub> phenotypes in patients with lactose intolerance symptoms and to analyze the birth-cohort phenomenon in lactose-intolerant patients. Method: 1266 patients consulted between 2010 and 2017 were enrolled. Five-year cohort periods of patients born before 1939 and after 1995 were defined and the prevalence of C\/T<jats:sub>13910<\/jats:sub> phenotypes was calculated. C\/T<jats:sub>13910<\/jats:sub> phenotypes were determined by polymerase chain reaction. Results: The prevalence of the CC phenotype was 43.1%, TC was detected in 44.3% and TT in 12.6% of the cases. The prevalence of the CC phenotype showed a non-linear incremental increase in females, from 9.13% in those born before 1939 to 37.7% in those born after 1995. Conclusion: The prevalence of CC phenotype raised incrementally in females, suggesting a gender\/hormonal influence. Orv Hetil. 2019; 160(14): 549\u2013554. <\/jats:p>","DOI":"10.1556\/650.2019.31332","type":"journal-article","created":{"date-parts":[[2019,3,31]],"date-time":"2019-03-31T02:46:34Z","timestamp":1554000394000},"page":"549-554","source":"Crossref","is-referenced-by-count":2,"title":["A feln\u0151ttkori hypolactasia                     sz\u00fclet\u00e9sikohorsz-vizsg\u00e1lata"],"prefix":"10.1556","volume":"160","author":[{"given":"Gy\u00f6rgy Mikl\u00f3s","family":"Buz\u00e1s","sequence":"first","affiliation":[{"name":"Ferencv\u00e1rosi Eg\u00e9szs\u00e9g\u00fcgyi Szolg\u00e1ltat\u00f3 K\u00f6zhaszn\u00fa Nonprofit Kft. Budapest, Mester u. 45., 1095"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","container-title":["Orvosi Hetilap"],"original-title":[],"language":"hu","link":[{"URL":"https:\/\/www.akademiai.com\/doi\/pdf\/10.1556\/650.2019.31332","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,4]],"date-time":"2019-04-04T09:35:29Z","timestamp":1554370529000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.akademiai.com\/doi\/10.1556\/650.2019.31332"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4]]},"references-count":0,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2019,4]]}},"alternative-id":["10.1556\/650.2019.31332"],"URL":"https:\/\/doi.org\/10.1556\/650.2019.31332","relation":{},"ISSN":["0030-6002","1788-6120"],"issn-type":[{"value":"0030-6002","type":"print"},{"value":"1788-6120","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4]]}}}