{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T17:36:47Z","timestamp":1649007407455},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"14","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orvosi Hetilap"],"published-print":{"date-parts":[[2019,4]]},"abstract":"<jats:p> Abstract: <\/jats:p><jats:p> Introduction: Levels of cardiac necroenzymes, high-sensitive troponin (hsTnT) and creatine kinase muscle-brain (CKMB) increase as a result of a myocardial damage following catheter ablation. Aim: To analyze the mid-term alteration of hsTnT and CKMB levels following radiofrequency ablation (RFCA) for atrial fibrillation (AF), atrial flutter (AFlu), AV-nodal reentry tachycardia (AVNRT) and electrophysiological studies (EPS) without ablation. Method: Patients undergoing RFCA for various indications and EPS were consecutively enrolled in our prospective study. Concentrations of hsTnT and CKMB were measured from serial blood samples directly before and after the procedure, 4 and 20 hours later and at 3 months follow-up. Results: Forty-seven patients (10 EPS, 12 AVNRT, 13 AFlu, 12 AF) with mean age of 55 \u00b1 13 were included. hsTnT levels increased significantly in all groups after the procedures, while CKMB changed only in the AF group. hsTnT exceeded the reference value in all patients with ablation and in 80% of patients with EPS 4 hours post-ablation. Peak average hsTnT levels for EPS, AVNRT, AFlu were 24 \u00b1 11, 260 \u00b1 218 and 541 \u00b1 233 ng\/L, respectively. The highest hsTnT level was measured in the AF group (799 \u00b1 433 ng\/L). We found a positive correlation between hsTnT levels and ablation time after RFCA. Conclusions: The hsTnT levels significantly change after EPS and RFCA, in all patients who underwent ablation, and in 80% of those with EPS had hsTnT positivity in the early post-procedural phase. hsTnT levels depended significantly on the type of the subgroups and correlated with the ablation time. Awareness of those observations is essential to correctly interpret elevated hsTnT levels following RFCA. Orv Hetil. 2019; 160(14): 540\u2013548. <\/jats:p>","DOI":"10.1556\/650.2019.31336","type":"journal-article","created":{"date-parts":[[2019,3,31]],"date-time":"2019-03-31T02:46:34Z","timestamp":1554000394000},"page":"540-548","source":"Crossref","is-referenced-by-count":0,"title":["A myocardialis necrosis m\u00e9rt\u00e9k\u00e9nek vizsg\u00e1lata elt\u00e9r\u0151                     supraventricularis sz\u00edvritmuszavarok r\u00e1di\u00f3frekvenci\u00e1s kat\u00e9terablati\u00f3s kezel\u00e9s\u00e9t                     k\u00f6vet\u0151en"],"prefix":"10.1556","volume":"160","author":[{"given":"Tam\u00e1s","family":"Tahin","sequence":"first","affiliation":[{"name":"V\u00e1rosmajori Sz\u00edv- \u00e9s \u00c9rgy\u00f3gy\u00e1szati Klinika,                         Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Budapest, V\u00e1rosmajor u. 68., 1122"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Szilvia","family":"Herczeg","sequence":"additional","affiliation":[{"name":"V\u00e1rosmajori Sz\u00edv- \u00e9s \u00c9rgy\u00f3gy\u00e1szati Klinika,                         Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Budapest, V\u00e1rosmajor u. 68., 1122"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00e1szl\u00f3","family":"Gell\u00e9r","sequence":"additional","affiliation":[{"name":"V\u00e1rosmajori Sz\u00edv- \u00e9s \u00c9rgy\u00f3gy\u00e1szati Klinika,                         Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Budapest, V\u00e1rosmajor u. 68., 1122"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e1s Mih\u00e1ly","family":"Boros","sequence":"additional","affiliation":[{"name":"V\u00e1rosmajori Sz\u00edv- \u00e9s \u00c9rgy\u00f3gy\u00e1szati Klinika,                         Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Budapest, V\u00e1rosmajor u. 68., 1122"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Orsolya M\u00e1ria","family":"Kov\u00e1cs","sequence":"additional","affiliation":[{"name":"V\u00e1rosmajori Sz\u00edv- \u00e9s \u00c9rgy\u00f3gy\u00e1szati Klinika,                         Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Budapest, V\u00e1rosmajor u. 68., 1122"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N\u00e1ndor","family":"Szegedi","sequence":"additional","affiliation":[{"name":"V\u00e1rosmajori Sz\u00edv- \u00e9s \u00c9rgy\u00f3gy\u00e1szati Klinika,                         Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Budapest, V\u00e1rosmajor u. 68., 1122"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c9va","family":"F\u00f3rizs","sequence":"additional","affiliation":[{"name":"V\u00e1rosmajori Sz\u00edv- \u00e9s \u00c9rgy\u00f3gy\u00e1szati Klinika,                         Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Budapest, V\u00e1rosmajor u. 68., 1122"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Szabolcs","family":"Szil\u00e1gyi","sequence":"additional","affiliation":[{"name":"V\u00e1rosmajori Sz\u00edv- \u00e9s \u00c9rgy\u00f3gy\u00e1szati Klinika,                         Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Budapest, V\u00e1rosmajor u. 68., 1122"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Istv\u00e1n","family":"Osztheimer","sequence":"additional","affiliation":[{"name":"V\u00e1rosmajori Sz\u00edv- \u00e9s \u00c9rgy\u00f3gy\u00e1szati Klinika,                         Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Budapest, V\u00e1rosmajor u. 68., 1122"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B\u00e9la","family":"Merkely","sequence":"additional","affiliation":[{"name":"V\u00e1rosmajori Sz\u00edv- \u00e9s \u00c9rgy\u00f3gy\u00e1szati Klinika,                         Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Budapest, V\u00e1rosmajor u. 68., 1122"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00e1bor","family":"Sz\u00e9plaki","sequence":"additional","affiliation":[{"name":"V\u00e1rosmajori Sz\u00edv- \u00e9s \u00c9rgy\u00f3gy\u00e1szati Klinika,                         Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Budapest, V\u00e1rosmajor u. 68., 1122"},{"name":"Heart and Vascular Centre, Mater Private Hospital Dublin, \u00cdrorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","container-title":["Orvosi Hetilap"],"original-title":[],"language":"hu","link":[{"URL":"https:\/\/www.akademiai.com\/doi\/pdf\/10.1556\/650.2019.31336","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,4]],"date-time":"2019-04-04T09:35:32Z","timestamp":1554370532000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.akademiai.com\/doi\/10.1556\/650.2019.31336"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4]]},"references-count":0,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2019,4]]}},"alternative-id":["10.1556\/650.2019.31336"],"URL":"https:\/\/doi.org\/10.1556\/650.2019.31336","relation":{},"ISSN":["0030-6002","1788-6120"],"issn-type":[{"value":"0030-6002","type":"print"},{"value":"1788-6120","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4]]}}}