{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T17:22:08Z","timestamp":1789924928978,"version":"4.0.1"},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"32","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Orvosi Hetilap"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:p> Abstract: <\/jats:p><jats:p> Introduction: During recent decades, the perinatal mortality of extremely low-birth weight infants has decreased. An important task is to recognize complications of prematurity. Aim: We made an attempt to explore the relationship between complications of prematurity and neonatal hyperglycemia. Method: From 1 January 2014 to 31 December 2017, 188 infants with birth weight below 1000 g were admitted. For each infant, the frequencies of hyperglycemia (blood glucose &gt;8.5 mmol\/l), retinopathy of prematurity, intraventricular hemorrhage, and bronchopulmonary dysplasia were determined. Animal studies were performed in Sprague Dawley rats. Hyperglycemia was achieved by intraperitoneal injection of streptozotocin (100 mg\/kg). On the 7th day of life, aorta sections were prepared and stained with hematoxylin eosin. Wall thickness was measured using QCapture Pro 7 image analysis software. Results: The mean \u00b1 SD gestational age and birth weight were 27.1 \u00b1 2.2 weeks and 814.9 \u00b1 151.9 g; 33 infants (17.5%) died. Hyperglycemia was confirmed in 62 cases (32.9%), and insulin treatment was given to 43 infants (22.8%). The gestational age and birth weight of the hyperglycemic infants were significantly lower (p&lt;0.001), the incidence of severe retinopathy (p = 0.012) and the mortality of insulin-treated patients were higher (p = 0.02) than in normoglycemic infants. Among survivors (n = 155), we found by logistic regression analysis that hyperglycemia was a risk factor for severe retinopathy (p&lt;0.001). In the rat model, neonatal hyperglycemia caused significant thickening of the aortic wall. Conclusion: Our studies indicate that hyperglycemia is common in extremely low birth-weight infants. Monitoring of these infants for retinopathy of prematurity, kidney dysfunction, and hypertension is recommended. Orv Hetil. 2019; 160(32): 1270\u20131278. <\/jats:p>","DOI":"10.1556\/650.2019.31455","type":"journal-article","created":{"date-parts":[[2019,8,7]],"date-time":"2019-08-07T05:36:50Z","timestamp":1565156210000},"page":"1270-1278","source":"Crossref","is-referenced-by-count":6,"title":["Az extr\u00e9m alacsony sz\u00fclet\u00e9si s\u00faly\u00fa korasz\u00fcl\u00f6ttek                     hyperglykaemi\u00e1j\u00e1nak korai \u00e9s k\u00e9s\u0151i sz\u00f6v\u0151dm\u00e9nyei"],"prefix":"10.1556","volume":"160","author":[{"given":"R\u00e9ka","family":"Turai","sequence":"first","affiliation":[{"name":"Klinikai K\u00f6zpont, Sz\u00fcl\u00e9szeti \u00e9s N\u0151gy\u00f3gy\u00e1szati Klinika,                     Neonatol\u00f3giai Tansz\u00e9k, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar P\u00e9cs, \u00c9desany\u00e1k \u00fatja 17., 7624"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1rton Ferenc","family":"Schandl","sequence":"additional","affiliation":[{"name":"Klinikai K\u00f6zpont, Sz\u00fcl\u00e9szeti \u00e9s N\u0151gy\u00f3gy\u00e1szati Klinika,                     Neonatol\u00f3giai Tansz\u00e9k, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar P\u00e9cs, \u00c9desany\u00e1k \u00fatja 17., 7624"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timea","family":"Dergez","sequence":"additional","affiliation":[{"name":"Bioanalitikai Int\u00e9zet, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar P\u00e9cs"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R\u00e9ka Anna","family":"Vass","sequence":"additional","affiliation":[{"name":"Klinikai K\u00f6zpont, Sz\u00fcl\u00e9szeti \u00e9s N\u0151gy\u00f3gy\u00e1szati Klinika,                     Neonatol\u00f3giai Tansz\u00e9k, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar P\u00e9cs, \u00c9desany\u00e1k \u00fatja 17., 7624"},{"name":"Anat\u00f3miai Int\u00e9zet, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar P\u00e9cs"},{"name":"MTA\u2013PTE Hum\u00e1n Reprodukci\u00f3s Kutat\u00f3csoport P\u00e9cs"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T\u00edmea","family":"Kv\u00e1rik","sequence":"additional","affiliation":[{"name":"Klinikai K\u00f6zpont, Sz\u00fcl\u00e9szeti \u00e9s N\u0151gy\u00f3gy\u00e1szati Klinika,                     Neonatol\u00f3giai Tansz\u00e9k, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar P\u00e9cs, \u00c9desany\u00e1k \u00fatja 17., 7624"},{"name":"Anat\u00f3miai Int\u00e9zet, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar P\u00e9cs"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eszter","family":"Hor\u00e1nyi","sequence":"additional","affiliation":[{"name":"Klinikai K\u00f6zpont, Sz\u00fcl\u00e9szeti \u00e9s N\u0151gy\u00f3gy\u00e1szati Klinika,                     Neonatol\u00f3giai Tansz\u00e9k, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar P\u00e9cs, \u00c9desany\u00e1k \u00fatja 17., 7624"},{"name":"Anat\u00f3miai Int\u00e9zet, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar P\u00e9cs"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorottya","family":"Balika","sequence":"additional","affiliation":[{"name":"Klinikai K\u00f6zpont, Sz\u00fcl\u00e9szeti \u00e9s N\u0151gy\u00f3gy\u00e1szati Klinika,                     Neonatol\u00f3giai Tansz\u00e9k, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar P\u00e9cs, \u00c9desany\u00e1k \u00fatja 17., 7624"},{"name":"Anat\u00f3miai Int\u00e9zet, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar 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Sz\u00fcl\u00e9szeti \u00e9s N\u0151gy\u00f3gy\u00e1szati Klinika,                     Neonatol\u00f3giai Tansz\u00e9k, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar P\u00e9cs, \u00c9desany\u00e1k \u00fatja 17., 7624"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9ria","family":"Ga\u00e1l","sequence":"additional","affiliation":[{"name":"Klinikai K\u00f6zpont, Szem\u00e9szeti Klinika, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar P\u00e9cs"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D\u00f3ra","family":"Regl\u0151di","sequence":"additional","affiliation":[{"name":"Anat\u00f3miai Int\u00e9zet, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar P\u00e9cs"},{"name":"MTA\u2013TKI PACAP Kutat\u00f3csoport P\u00e9cs"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tibor","family":"Ertl","sequence":"additional","affiliation":[{"name":"Klinikai K\u00f6zpont, Sz\u00fcl\u00e9szeti \u00e9s N\u0151gy\u00f3gy\u00e1szati Klinika,                     Neonatol\u00f3giai Tansz\u00e9k, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar P\u00e9cs, \u00c9desany\u00e1k \u00fatja 17., 7624"},{"name":"MTA\u2013PTE Hum\u00e1n Reprodukci\u00f3s Kutat\u00f3csoport P\u00e9cs"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","container-title":["Orvosi 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