{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T11:21:55Z","timestamp":1697800915864},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"1","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Absztrakt: <\/jats:title>\n        <jats:p>A Castleman-betegs\u00e9g egy ritka, lymphoproliferativ betegs\u00e9g, melynek pontos oka\n                    ismeretlen. Diagnosztik\u00e1j\u00e1nak alapja az adekv\u00e1t sz\u00f6vettani vizsg\u00e1lat. M\u00edg az\n                    unilocularis form\u00e1n\u00e1l a betegs\u00e9g a leggyakrabban a mellkast \u00e9rinti, \u00e9s az \u00e9pben\n                    t\u00f6rt\u00e9n\u0151 seb\u00e9szi elt\u00e1vol\u00edt\u00e1s a t\u00fcnetek megsz\u0171n\u00e9s\u00e9t eredm\u00e9nyezheti, addig a\n                    multilocularis form\u00e1n\u00e1l egy\u00e9b kezel\u00e9si form\u00e1k eg\u00e9sz\u00edthetik ki vagy v\u00e1lthatj\u00e1k\n                    fel a m\u0171t\u00e9ti elt\u00e1vol\u00edt\u00e1st. Munk\u00e1nkban egy Castleman-betegs\u00e9g miatt\n                    multidiszciplin\u00e1ris kezel\u00e9sen \u00e1tesett beteg eset\u00e9t mutatjuk be. Az 56 \u00e9ves f\u00e9rfi\n                    betegn\u00e9l kivizsg\u00e1l\u00e1sa el\u0151tt 18 h\u00e9ttel, egy fels\u0151 l\u00e9g\u00fati infekci\u00f3t k\u00f6vet\u0151en\n                    besz\u00e9dnehez\u00edtetts\u00e9g, nyel\u00e9szavar, fels\u0151 \u00e9s als\u00f3 v\u00e9gtagi progressz\u00edv paresis\n                    jelentkezett. Plazmafer\u00e9zisre a beteg panaszai \u00e1tmenetileg megsz\u0171ntek ugyan, de\n                    a seb\u00e9szi mintav\u00e9telek a mellkas-CT-n l\u00e1tott mediastinalis lymphadenomegalia\n                    eredet\u00e9t nem tudt\u00e1k igazolni. \u00cdgy az 5 cm-es subcarinalis nyirokcsom\u00f3\n                    elt\u00e1vol\u00edt\u00e1sa vagy mintav\u00e9telez\u00e9se miatt ker\u00fclt a beteg oszt\u00e1lyunkra. \u00c1tv\u00e9telkor\n                    mind a n\u00e9gy v\u00e9gtagon jelent\u0151s atr\u00f3fia, hipot\u00f3nia, tetraplegia volt l\u00e1that\u00f3, \u00e9s\n                    testszerte areflexia igazol\u00f3dott. Oszt\u00e1lyunkon posterolateralis thoracotomi\u00e1b\u00f3l\n                    elt\u00e1vol\u00edtottuk az 5,5 \u00d7 3,5 cm-es subcarinalis nyirokcsom\u00f3-konglomer\u00e1tumot. A\n                    sz\u00f6vettani vizsg\u00e1lat Castleman-betegs\u00e9get jelzett. 3 nappal a m\u0171t\u00e9t ut\u00e1n a\n                    v\u00e9gtagok mozg\u00e1sa megindult, a 9. napon m\u00e1r j\u00e1r\u00f3kerettel j\u00e1r\u00f3k\u00e9pess\u00e9 v\u00e1lt, ezt\n                    k\u00f6vet\u0151en neurol\u00f3giai rehabilit\u00e1ci\u00f3s oszt\u00e1lyra ker\u00fclt. Ekkor a fels\u0151 v\u00e9gtagokban\n                    k\u00f6zel megtartott, m\u00edg az als\u00f3 v\u00e9gtagokban 4\/5-\u00f6s izomer\u0151t \u00e9szleltek. Ezt\n                    k\u00f6vet\u0151en a beteg metilprednizolon-, B<jats:sub>1<\/jats:sub>-vitamin-, kalcium-citr\u00e1t- \u00e9s\n                    famotidinkezel\u00e9sben r\u00e9szes\u00fclt; 2 h\u00e9ttel \u00e1tv\u00e9tele ut\u00e1n otthon\u00e1ba bocs\u00e1tott\u00e1k,\n                    ekkor m\u00e1r j\u00e1r\u00f3keret n\u00e9lk\u00fcl biztons\u00e1gosan k\u00f6zlekedett. T\u00fcnetei 3 h\u00f3nappal a m\u0171t\u00e9t\n                    ut\u00e1n csaknem teljes m\u00e9rt\u00e9kben megsz\u0171ntek. A Castleman-betegs\u00e9g diagnosztik\u00e1ja \u00e9s\n                    kezel\u00e9se multidiszciplin\u00e1ris feladat. Ha a p\u00e1ciens m\u0171t\u00e9ti teherb\u00edr\u00f3 k\u00e9pess\u00e9ge\n                    engedi, akkor az unilocularis Castleman-betegs\u00e9g ter\u00e1pi\u00e1s eszk\u00f6zt\u00e1r\u00e1ban a\n                    seb\u00e9szeti elt\u00e1vol\u00edt\u00e1snak kiemelt szerepe kell, hogy legyen. OrvHetil. 2020;\n                    161(1): 33\u201338.<\/jats:p>","DOI":"10.1556\/650.2020.31560","type":"journal-article","created":{"date-parts":[[2019,12,29]],"date-time":"2019-12-29T08:02:47Z","timestamp":1577606567000},"page":"33-38","update-policy":"http:\/\/dx.doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":1,"title":["Tetraplegia sikeres multidiszciplin\u00e1ris kezel\u00e9se mellkasseb\u00e9szeti m\u0171t\u00e9ttel. Unicentrikus mediastinalis Castleman-betegs\u00e9g esete"],"prefix":"10.1556","volume":"161","author":[{"given":"Tibor","family":"N\u00e9meth","sequence":"first","affiliation":[{"name":"1 Seb\u00e9szeti Klinika, Szegedi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi KarSzeged, Semmelweis u. 8., 6725"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bal\u00e1zs","family":"P\u00e9csy","sequence":"additional","affiliation":[{"name":"1 Seb\u00e9szeti Klinika, Szegedi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi KarSzeged, Semmelweis u. 8., 6725"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tibor","family":"G\u00e9czi","sequence":"additional","affiliation":[{"name":"1 Seb\u00e9szeti Klinika, Szegedi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi KarSzeged, Semmelweis u. 8., 6725"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katalin","family":"Sas","sequence":"additional","affiliation":[{"name":"2 Neurol\u00f3giai Klinika, Szegedi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi KarSzeged"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00e1szl\u00f3","family":"Szpisjak","sequence":"additional","affiliation":[{"name":"2 Neurol\u00f3giai Klinika, Szegedi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi KarSzeged"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Rieth","sequence":"additional","affiliation":[{"name":"3 Gyermekgy\u00f3gy\u00e1szati Klinika, Szegedi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi KarSzeged"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Val\u00e9ria","family":"Kiss","sequence":"additional","affiliation":[{"name":"4 Neurol\u00f3giai Oszt\u00e1ly, J\u00e1sz-Nagykun Szolnok Megyei Het\u00e9nyi G\u00e9za K\u00f3rh\u00e1z-Rendel\u0151int\u00e9zetSzolnok"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferenc","family":"Sz\u0151nyegi","sequence":"additional","affiliation":[{"name":"4 Neurol\u00f3giai Oszt\u00e1ly, J\u00e1sz-Nagykun Szolnok Megyei Het\u00e9nyi G\u00e9za K\u00f3rh\u00e1z-Rendel\u0151int\u00e9zetSzolnok"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00e1szl\u00f3","family":"Tiszlavicz","sequence":"additional","affiliation":[{"name":"5 Pathologiai Int\u00e9zet, Szegedi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi KarSzeged"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tam\u00e1s","family":"Zombori","sequence":"additional","affiliation":[{"name":"5 Pathologiai Int\u00e9zet, Szegedi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi KarSzeged"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gy\u00f6rgy","family":"L\u00e1z\u00e1r","sequence":"additional","affiliation":[{"name":"1 Seb\u00e9szeti Klinika, Szegedi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi KarSzeged, Semmelweis u. 8., 6725"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00f3zsef","family":"Fur\u00e1k","sequence":"additional","affiliation":[{"name":"1 Seb\u00e9szeti Klinika, Szegedi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi KarSzeged, Semmelweis u. 8., 6725"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","container-title":["Orvosi Hetilap"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/650\/161\/1\/article-p33.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/downloadpdf\/journals\/650\/161\/1\/article-p33.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,11]],"date-time":"2021-10-11T01:13:27Z","timestamp":1633914807000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/view\/journals\/650\/161\/1\/article-p33.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":0,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.1556\/650.2020.31560","relation":{},"ISSN":["0030-6002","1788-6120"],"issn-type":[{"value":"0030-6002","type":"print"},{"value":"1788-6120","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1]]}}}