{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T16:44:28Z","timestamp":1778949868354,"version":"3.51.4"},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"1","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Absztrakt: <\/jats:title>\n        <jats:p>A repetit\u00edv transcranialis m\u00e1gneses stimul\u00e1ci\u00f3s elj\u00e1r\u00e1s egy olyan neuromodul\u00e1ci\u00f3s\n                    technika, melynek gyorsan fejl\u0151d\u0151 ter\u00fclete jelentheti az egyik biztons\u00e1gos,\n                    alternat\u00edv megk\u00f6zel\u00edt\u00e9si m\u00f3dot bizonyos ment\u00e1lis zavarok, els\u0151sorban a\n                    ter\u00e1piarezisztens major depressz\u00edv zavar kezel\u00e9s\u00e9ben. C\u00e9lunk a transcranialis\n                    m\u00e1gneses stimul\u00e1ci\u00f3s kezel\u00e9s jelenlegi kutat\u00e1si \u00e9s klinikai alkalmaz\u00e1si\n                    lehet\u0151s\u00e9geinek bemutat\u00e1sa a szakirodalmi adatok \u00e9s a klinikai gyakorlat\n                    \u00e1ttekint\u00e9se alapj\u00e1n. Mi\u00f3ta ismertt\u00e9 v\u00e1lt, hogy k\u00fcls\u0151 m\u00e1gneses forr\u00e1ssal neuronok\n                    depolariz\u00e1lhat\u00f3k, mind a neurol\u00f3gia, mind a pszichi\u00e1tria az elj\u00e1r\u00e1s lehets\u00e9ges\n                    klinikai haszn\u00e1lat\u00e1t kutatja. Napjainkig a m\u00f3dszer a pszichi\u00e1tria ter\u00fclet\u00e9n\n                    bel\u00fcl a major depressz\u00edv zavar \u00e9s a k\u00e9nyszeres zavar kezel\u00e9s\u00e9ben enged\u00e9lyezett,\n                    de egy\u00e9b betegs\u00e9gek (p\u00e9ld\u00e1ul szkizofr\u00e9nia, bipol\u00e1ris zavar) kezel\u00e9s\u00e9ben is\n                    kutatj\u00e1k lehets\u00e9ges alkalmaz\u00e1s\u00e1t. A transcranialis m\u00e1gneses stimul\u00e1ci\u00f3s\n                    rendszerek fejleszt\u00e9s\u00e9nek k\u00f6vetkez\u0151 l\u00e9pcs\u0151j\u00e9t jelenti a\n                    m\u00e1gnesesrezonancia-felv\u00e9tel alapj\u00e1n, helymeghat\u00e1roz\u00f3 algoritmusok seg\u00edts\u00e9g\u00e9vel,\n                    val\u00f3s id\u0151ben navig\u00e1lt m\u00e1gneses stimul\u00e1ci\u00f3s k\u00e9sz\u00fcl\u00e9kek kidolgoz\u00e1sa. Az\n                    \u00fagynevezett neuronavig\u00e1ci\u00f3s rendszerek lehet\u0151v\u00e9 teszik a depresszi\u00f3\n                    kialakul\u00e1s\u00e1\u00e9rt felel\u0151s idegi h\u00e1l\u00f3zatok pontos c\u00e9lz\u00e1s\u00e1t, \u00edgy a dorsolateralis\n                    praefrontalis k\u00e9reg excitabilit\u00e1s\u00e1nak fokoz\u00e1s\u00e1t a bal f\u00e9ltek\u00e9n \u00e9s cs\u00f6kkent\u00e9s\u00e9t a\n                    jobb f\u00e9ltek\u00e9n. Az elj\u00e1r\u00e1s kev\u00e9s kontraindik\u00e1ci\u00f3val b\u00edr, \u00e9s a megfelel\u0151\n                    k\u00f6r\u00fcltekint\u00e9ssel v\u00e1lasztott indik\u00e1ci\u00f3 \u00e9s betegpopul\u00e1ci\u00f3 eset\u00e9n mell\u00e9khat\u00e1sok is\n                    alacsony sz\u00e1mban jelentkeznek. A transcranialis m\u00e1gneses stimul\u00e1ci\u00f3s kezel\u00e9s\n                    m\u00e1ra bizony\u00edtottan hat\u00e9kony m\u00f3dszerr\u00e9 v\u00e1lt bizonyos ment\u00e1lis zavarok, els\u0151sorban\n                    a ter\u00e1piarezisztens major depressz\u00edv zavar kezel\u00e9s\u00e9ben. A j\u00f6v\u0151ben a\n                    neuronavig\u00e1ci\u00f3s neuromodul\u00e1ci\u00f3s kezel\u00e9sek, azon bel\u00fcl is a repetit\u00edv\n                    transcranialis m\u00e1gneses stimul\u00e1ci\u00f3s kezel\u00e9s t\u00e9rh\u00f3d\u00edt\u00e1sa v\u00e1rhat\u00f3 a pszichi\u00e1tria\n                    \u00e9s a neurol\u00f3gia ter\u00fclet\u00e9n. Jelenleg Magyarorsz\u00e1gon t\u00f6bb centrumban is v\u00e9geznek\n                    k\u00fcl\u00f6nb\u00f6z\u0151 indik\u00e1ci\u00f3kban m\u00e1gneses stimul\u00e1ci\u00f3s kezel\u00e9seket, \u00e1m az elj\u00e1r\u00e1s ment\u00e1lis\n                    zavarokban t\u00f6rt\u00e9n\u0151 alkalmaz\u00e1s\u00e1nak finansz\u00edroz\u00e1si befogad\u00e1sa \u00e9s be\u00e9p\u00edt\u00e9se a\n                    mindennapi klinikai gyakorlatba m\u00e9g v\u00e1rat mag\u00e1ra. Orv Hetil. 2020; 161(1):\n                    3\u201310.<\/jats:p>","DOI":"10.1556\/650.2020.31611","type":"journal-article","created":{"date-parts":[[2019,12,29]],"date-time":"2019-12-29T08:02:47Z","timestamp":1577606567000},"page":"3-10","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":2,"title":["A repetit\u00edv transcranialis m\u00e1gneses stimul\u00e1ci\u00f3 szerepe a ment\u00e1lis zavarok, els\u0151sorban a ter\u00e1piarezisztens major depressz\u00edv zavar kezel\u00e9s\u00e9ben"],"prefix":"10.1556","volume":"161","author":[{"given":"R\u00f3bert","family":"Pilisi","sequence":"first","affiliation":[{"name":"1 Klinikai K\u00f6zpont, Pszichi\u00e1triai \u00e9s Pszichoter\u00e1pi\u00e1s Klinika, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi KarP\u00e9cs, R\u00e9t u. 2., 7623"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tam\u00e1s","family":"T\u00e9nyi","sequence":"additional","affiliation":[{"name":"1 Klinikai K\u00f6zpont, Pszichi\u00e1triai \u00e9s Pszichoter\u00e1pi\u00e1s Klinika, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi KarP\u00e9cs, R\u00e9t u. 2., 7623"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e1s","family":"B\u00fcki","sequence":"additional","affiliation":[{"name":"2 Klinikai K\u00f6zpont, Idegseb\u00e9szeti Klinika, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi KarP\u00e9cs"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norbert","family":"Kov\u00e1cs","sequence":"additional","affiliation":[{"name":"3 Klinikai K\u00f6zpont, Neurol\u00f3giai Klinika, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi KarP\u00e9cs"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antal","family":"Zempl\u00e9nyi","sequence":"additional","affiliation":[{"name":"4 Gy\u00f3gyszer\u00e9szeti Int\u00e9zet, Farmako\u00f6kon\u00f3mia Tansz\u00e9k, P\u00e9csi Tudom\u00e1nyegyetem, Gy\u00f3gyszer\u00e9sztudom\u00e1nyi KarP\u00e9cs"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriella","family":"Sebesty\u00e9n","sequence":"additional","affiliation":[{"name":"2 Klinikai K\u00f6zpont, Idegseb\u00e9szeti Klinika, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi KarP\u00e9cs"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P\u00e9ter","family":"Osv\u00e1th","sequence":"additional","affiliation":[{"name":"1 Klinikai K\u00f6zpont, Pszichi\u00e1triai \u00e9s Pszichoter\u00e1pi\u00e1s Klinika, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi KarP\u00e9cs, R\u00e9t u. 2., 7623"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00e1ndor","family":"Fekete","sequence":"additional","affiliation":[{"name":"1 Klinikai K\u00f6zpont, Pszichi\u00e1triai \u00e9s Pszichoter\u00e1pi\u00e1s Klinika, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi KarP\u00e9cs, R\u00e9t u. 2., 7623"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viktor","family":"V\u00f6r\u00f6s","sequence":"additional","affiliation":[{"name":"1 Klinikai K\u00f6zpont, Pszichi\u00e1triai \u00e9s Pszichoter\u00e1pi\u00e1s Klinika, P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi KarP\u00e9cs, R\u00e9t u. 2., 7623"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","container-title":["Orvosi Hetilap"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/650\/161\/1\/article-p3.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/downloadpdf\/journals\/650\/161\/1\/article-p3.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,11]],"date-time":"2021-10-11T01:13:25Z","timestamp":1633914805000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/view\/journals\/650\/161\/1\/article-p3.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":0,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.1556\/650.2020.31611","relation":{},"ISSN":["0030-6002","1788-6120"],"issn-type":[{"value":"0030-6002","type":"print"},{"value":"1788-6120","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1]]}}}