{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T22:53:25Z","timestamp":1778626405161,"version":"3.51.4"},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"2","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2020,1]]},"abstract":"Absztrakt: <\/jats:title>\n \n Bevezet\u00e9s:<\/jats:italic> A leped\u00e9kkel, t\u00fcsz\u0151kkel fedett, gyulladt tonsilla\n gyakori elv\u00e1ltoz\u00e1snak sz\u00e1m\u00edt a gyermekgy\u00f3gy\u00e1szatban. A t\u00fcnet h\u00e1tter\u00e9ben az\n esetek nagyobb r\u00e9sz\u00e9ben v\u00edrusfert\u0151z\u00e9s (Epstein\u2013Barr-v\u00edrus [EBV], cytomegalovirus\n [CMV], influenza, parainfluenza, adenov\u00edrus) \u00e1ll; csak kisebb ar\u00e1nyban\n bakt\u00e9riumok, melyek k\u00f6z\u00fcl az A-csoport\u00fa streptococcusok \u00e1ltal okozott fert\u0151z\u00e9s\n kiemelend\u0151. A jelenlegi ir\u00e1nyelvek alapj\u00e1n nem aj\u00e1nlott rutinszer\u0171, prevent\u00edv\n antibiotikumkezel\u00e9s az A-csoport\u00fa streptococcusok \u00e1ltal okozott sz\u00f6v\u0151dm\u00e9nyek\n megel\u0151z\u00e9s\u00e9re. C\u00e9lkit\u0171z\u00e9s:<\/jats:italic> C\u00e9lunk volt meghat\u00e1rozni, hogy a\n leped\u00e9kes tonsillitis miatt felvett gyermekek eset\u00e9n jelenthet-e\n differenci\u00e1ldiagnosztikai seg\u00edts\u00e9get a laborat\u00f3riumi \u00e9rt\u00e9kek v\u00e1ltoz\u00e1sa a\n felesleges antibiotikumhaszn\u00e1lat elker\u00fcl\u00e9s\u00e9ben. M\u00f3dszer:<\/jats:italic> A\n vizsg\u00e1lat sor\u00e1n 133 beteg 135, exsudativ tonsillitis miatt t\u00f6rt\u00e9nt\n megjelen\u00e9s\u00e9nek adatait elemezt\u00fck. A betegeket k\u00e9t csoportba osztottuk. Az 1.\n csoportba ker\u00fcltek azok a betegek, akikn\u00e9l EBV vagy CMV k\u00f3roki szerepe volt\n igazolhat\u00f3, m\u00edg a 2. csoportba azokat a betegeket soroltuk, akikn\u00e9l szerol\u00f3giai\n m\u00f3dszerekkel nem volt igazolhat\u00f3 v\u00edrusfert\u0151z\u00e9s. Eredm\u00e9nyek:<\/jats:italic> A\n vizsg\u00e1lati eredm\u00e9nyek alapj\u00e1n 2016 \u00e9s 2017 k\u00f6z\u00f6tt az exsudativ tonsillitisek\n t\u00f6bbs\u00e9g\u00e9n\u00e9l (66\/135, 48,8%) a CMV \u00e9s az EBV k\u00f3roki szerepe volt igazolhat\u00f3\n szerol\u00f3giai m\u00f3dszerrel, m\u00edg Streptococcus pyogenes<\/jats:italic> jelenl\u00e9te\n csak n\u00e9h\u00e1ny esetben (3\/65, 4,61%) volt kimutathat\u00f3 torokv\u00e1lad\u00e9kb\u00f3l. A betegek\n jelent\u0151s, 92%-a a fentiek ellen\u00e9re antibiotikumkezel\u00e9sben r\u00e9szes\u00fclt.\n K\u00f6vetkeztet\u00e9s:<\/jats:italic> Retrospekt\u00edv felm\u00e9r\u00e9s\u00fcnk eredm\u00e9nyei is\n al\u00e1t\u00e1masztott\u00e1k, hogy a klinikai t\u00fcnetek \u00e9s a fizik\u00e1lis status alapj\u00e1n nem\n lehets\u00e9ges a k\u00f3roki t\u00e9nyez\u0151t meg\u00edt\u00e9lni, s\u0151t a legt\u00f6bb esetben a kvalitat\u00edv\n v\u00e9rk\u00e9p elt\u00e9r\u00e9sei \u00e9s a gyullad\u00e1sos markerek \u2013 p\u00e9ld\u00e1ul a C-reakt\u00edv protein (CRP) \u2013\n emelked\u00e9se sem jelez egy\u00e9rtelm\u0171en bakteri\u00e1lis infekci\u00f3t. Ellenben a\n transzamin\u00e1z\u00e9rt\u00e9kek emelked\u00e9se magas pozit\u00edv predikt\u00edv \u00e9rt\u00e9kkel utal\n v\u00edrusfert\u0151z\u00e9sre, azon bel\u00fcl is a vizsg\u00e1lat t\u00e1rgy\u00e1t k\u00e9pez\u0151 CMV- \u00e9s\n EBV-infekci\u00f3ra. A laborvizsg\u00e1latok ez ir\u00e1ny\u00fa kiterjeszt\u00e9s\u00e9vel a felesleges\n antibiotikumhaszn\u00e1lat jelent\u0151sen cs\u00f6kkenthet\u0151. Orv Hetil. 2020; 161(2):\n 50\u201355.<\/jats:p>","DOI":"10.1556\/650.2020.31618","type":"journal-article","created":{"date-parts":[[2020,1,5]],"date-time":"2020-01-05T13:26:27Z","timestamp":1578230787000},"page":"50-55","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":6,"title":["Leped\u00e9kes tonsilla gyermekkorban. Hogyan cs\u00f6kkenthet\u0151 az indokolatlan antibiotikumfelhaszn\u00e1l\u00e1s?"],"prefix":"10.1556","volume":"161","author":[{"given":"Andrea","family":"Tak\u00e1cs","sequence":"first","affiliation":[{"name":"1 Gyermekgy\u00f3gy\u00e1szati Klinika \u00e9s Gyermek-Eg\u00e9szs\u00e9g\u00fcgyi K\u00f6zpont, Szegedi Tudom\u00e1nyegyetem, Szent-Gy\u00f6rgyi Albert Klinikai K\u00f6zpontSzeged"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D\u00e1niel","family":"Sz\u0171cs","sequence":"additional","affiliation":[{"name":"1 Gyermekgy\u00f3gy\u00e1szati Klinika \u00e9s Gyermek-Eg\u00e9szs\u00e9g\u00fcgyi K\u00f6zpont, Szegedi Tudom\u00e1nyegyetem, Szent-Gy\u00f6rgyi Albert Klinikai K\u00f6zpontSzeged"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriella","family":"Terhes","sequence":"additional","affiliation":[{"name":"2 Klinikai Mikrobiol\u00f3giai Diagnosztikai Int\u00e9zet, Szegedi Tudom\u00e1nyegyetem, Szent-Gy\u00f6rgyi Albert Klinikai K\u00f6zpontSzeged, Semmelweis u. 6., 6725"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","container-title":["Orvosi Hetilap"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/650\/161\/2\/article-p50.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/downloadpdf\/journals\/650\/161\/2\/article-p50.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,11]],"date-time":"2021-10-11T01:12:44Z","timestamp":1633914764000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/view\/journals\/650\/161\/2\/article-p50.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":0,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.1556\/650.2020.31618","relation":{},"ISSN":["0030-6002","1788-6120"],"issn-type":[{"value":"0030-6002","type":"print"},{"value":"1788-6120","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1]]}}}