{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,3,14]],"date-time":"2024-03-14T07:22:11Z","timestamp":1710400931607},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"6","license":[{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:title>Absztrakt: <\/jats:title>\n        <jats:p>\n          <jats:italic>Bevezet\u00e9s:<\/jats:italic> A multifaktori\u00e1lis, nem teljesen tiszt\u00e1zott\n                    patomechanizmus\u00fa, gy\u00f3gyszer okozta \u00e1llcsontelhal\u00e1s kezel\u00e9se napjainkban is nagy\n                    kih\u00edv\u00e1st jelent a maxillofacialis seb\u00e9szek \u00e9s fogorvosok, valamint az onkol\u00f3giai\n                    \u00e9s oszteol\u00f3giai gy\u00f3gyszert fel\u00edr\u00f3 kezel\u0151orvosok sz\u00e1m\u00e1ra.\n                        <jats:italic>C\u00e9lkit\u0171z\u00e9s:<\/jats:italic> K\u00f6zlem\u00e9ny\u00fcnkben c\u00e9lul t\u0171zt\u00fck ki, hogy az\n                    aktu\u00e1lis szakirodalom \u00e1ttekint\u00e9s\u00e9t k\u00f6vet\u0151en bemutassuk a v\u00e1ltoz\u00e1sokat a\n                    gy\u00f3gyszer okozta \u00e1llcsontelhal\u00e1sok patogenezis\u00e9nek, rizik\u00f3t\u00e9nyez\u0151inek, klinikai\n                    megjelen\u00e9si form\u00e1inak, illetve a megel\u0151z\u00e9si \u00e9s az \u00faj ter\u00e1pi\u00e1s lehet\u0151s\u00e9geknek a\n                    tekintet\u00e9ben. Az el\u00e9rhet\u0151 nemzetk\u00f6zi aj\u00e1nl\u00e1sok \u00f6sszehasonl\u00edt\u00e1s\u00e1n, a nem seb\u00e9szi\n                    \u00e9s a seb\u00e9szi, valamint a st\u00e1diumspecifikus kezel\u00e9si m\u00f3dok evidenciaalap\u00fa\n                    bemutat\u00e1s\u00e1n t\u00fal a k\u00fcl\u00f6nb\u00f6z\u0151 orvosi-fogorvosi diszciplin\u00e1kat \u00e9rint\u0151 specifikumok\n                    bemutat\u00e1s\u00e1ra is t\u00f6reksz\u00fcnk. <jats:italic>M\u00f3dszer:<\/jats:italic> Az elm\u00falt 5 \u00e9vben \u2013 az\n                    egyre n\u00f6vekv\u0151 sz\u00e1m\u00fa betegs\u00e9gorient\u00e1lt adatb\u00e1zisnak k\u00f6sz\u00f6nhet\u0151en \u2013 a\n                    szakirodalomban megn\u0151tt a szisztematikus szakirodalmi \u00e1ttekint\u00e9sek (systematic\n                    reviews), aj\u00e1nl\u00e1sok \u00e9s metaanal\u00edzisek sz\u00e1ma; ezek \u00e1ttekint\u00e9s\u00e9t \u00e9s \u00f6sszehasonl\u00edt\u00f3\n                    elemz\u00e9s\u00e9t v\u00e9gezt\u00fck el a kit\u0171z\u00f6tt c\u00e9lok vonatkoz\u00e1s\u00e1ban.\n                        <jats:italic>Eredm\u00e9nyek:<\/jats:italic> Az American Association of Oral and\n                    Maxillofacial Surgeons munkacsoportj\u00e1nak legut\u00f3bbi aj\u00e1nl\u00e1sa \u00f3ta eltelt 4 \u00e9vben\n                    is sz\u00e1mos \u00faj gy\u00f3gyszerhat\u00e1stani csoport ker\u00fclt a klinikusok l\u00e1t\u00f3k\u00f6r\u00e9be mint\n                    osteonecrosist induk\u00e1l\u00f3 potenci\u00e1lis \u00e1gens, \u00edgy a betegs\u00e9g n\u00f3menklat\u00far\u00e1ja tov\u00e1bb\n                    cizell\u00e1l\u00f3dott, a betegcsoportok tov\u00e1bb specifik\u00e1l\u00f3dtak. A rizik\u00f3betegek k\u00f6re\n                    kisz\u00e9lesedett, \u00faj betegpopul\u00e1ci\u00f3knak (reumatol\u00f3giai-oszteol\u00f3giai betegek,\n                    immunszupprim\u00e1ltak, transzplant\u00e1ltak, \u00faj onkol\u00f3giai \u2019target\u2019 [c\u00e9lzott]\n                    ter\u00e1pi\u00e1ban r\u00e9szes\u00fcl\u0151k) kell a s\u00falyos mell\u00e9khat\u00e1s kialakul\u00e1s\u00e1val sz\u00e1molniuk.\n                        <jats:italic>K\u00f6vetkeztet\u00e9s:<\/jats:italic> Noha a betegcsoport kezel\u00e9s\u00e9ben sz\u00e1mos\n                    k\u00e9rd\u00e9s tov\u00e1bbra is nyitva \u00e1ll, a kor\u00e1bbi empirikus kezel\u00e9si form\u00e1k helyett egyre\n                    er\u0151sebb evidenci\u00e1kon alapul\u00f3, egy\u00e9nspecifikus, st\u00e1diumadapt\u00e1lt ter\u00e1pi\u00e1s\n                    megold\u00e1sok k\u00f6rvonalaz\u00f3dnak. Orv Hetil. 2020; 161(6): 214\u2013223.<\/jats:p>","DOI":"10.1556\/650.2020.31633","type":"journal-article","created":{"date-parts":[[2020,2,2]],"date-time":"2020-02-02T13:50:17Z","timestamp":1580651417000},"page":"214-223","update-policy":"http:\/\/dx.doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":2,"title":["Aktualit\u00e1sok a gy\u00f3gyszer okozta \u00e1llcsontelhal\u00e1s primer \u00e9s szekunder prevenci\u00f3j\u00e1nak strat\u00e9gi\u00e1j\u00e1ban az evidenci\u00e1k \u00e9s a nemzetk\u00f6zi aj\u00e1nl\u00e1sok t\u00fckr\u00e9ben"],"prefix":"10.1556","volume":"161","author":[{"given":"Tam\u00e1s","family":"Vereb","sequence":"first","affiliation":[{"name":"Szent-Gy\u00f6rgyi Albert Klinikai K\u00f6zpont, Arc-, \u00c1llcsont- \u00e9s Sz\u00e1jseb\u00e9szeti Klinika, Szegedi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi KarSzeged, K\u00e1lv\u00e1ria sgt. 57., 6725"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c1gnes","family":"Janovszky","sequence":"additional","affiliation":[{"name":"Szent-Gy\u00f6rgyi Albert Klinikai K\u00f6zpont, Arc-, \u00c1llcsont- \u00e9s Sz\u00e1jseb\u00e9szeti Klinika, Szegedi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi KarSzeged, K\u00e1lv\u00e1ria sgt. 57., 6725"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marietta","family":"Mucsi","sequence":"additional","affiliation":[{"name":"Szent-Gy\u00f6rgyi Albert Klinikai K\u00f6zpont, Arc-, \u00c1llcsont- \u00e9s Sz\u00e1jseb\u00e9szeti Klinika, Szegedi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi KarSzeged, K\u00e1lv\u00e1ria sgt. 57., 6725"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00f3zsef","family":"Piffk\u00f3","sequence":"additional","affiliation":[{"name":"Szent-Gy\u00f6rgyi Albert Klinikai K\u00f6zpont, Arc-, \u00c1llcsont- \u00e9s Sz\u00e1jseb\u00e9szeti Klinika, Szegedi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi KarSzeged, K\u00e1lv\u00e1ria sgt. 57., 6725"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00e1szl\u00f3","family":"Seres","sequence":"additional","affiliation":[{"name":"Szent-Gy\u00f6rgyi Albert Klinikai K\u00f6zpont, Arc-, \u00c1llcsont- \u00e9s Sz\u00e1jseb\u00e9szeti Klinika, Szegedi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi KarSzeged, K\u00e1lv\u00e1ria sgt. 57., 6725"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","container-title":["Orvosi Hetilap"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/650\/161\/6\/article-p214.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/downloadpdf\/journals\/650\/161\/6\/article-p214.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,11]],"date-time":"2021-10-11T01:12:25Z","timestamp":1633914745000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/view\/journals\/650\/161\/6\/article-p214.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2]]},"references-count":0,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.1556\/650.2020.31633","relation":{},"ISSN":["0030-6002","1788-6120"],"issn-type":[{"value":"0030-6002","type":"print"},{"value":"1788-6120","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,2]]}}}