{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T20:13:19Z","timestamp":1775851999038,"version":"3.50.1"},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"35","license":[{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2020,8]]},"abstract":"Absztrakt: <\/jats:title>\n Bevezet\u00e9s:<\/jats:italic> A swept source optikaikoherencia-tomogr\u00e1fia egy \u00faj,\n noninvaz\u00edv eszk\u00f6z, amely lehet\u0151v\u00e9 teszi a retina mellett a chorioidea\n vizsg\u00e1lat\u00e1t, \u00e9s seg\u00edts\u00e9get ny\u00fajthat a diabeteses chorioidopathia patogenezis\u00e9nek\n megismer\u00e9s\u00e9ben. C\u00e9lkit\u0171z\u00e9s:<\/jats:italic> Diabeteses retinopathia k\u00fcl\u00f6nb\u00f6z\u0151\n s\u00falyoss\u00e1g\u00fa st\u00e1diumaiban a chorioideavastags\u00e1g meghat\u00e1roz\u00e1sa, valamint a\n k\u00fcl\u00f6nb\u00f6z\u0151 ter\u00e1pi\u00e1s lehet\u0151s\u00e9gek \u00e9s a j\u00f3l ismert \u00e1ltal\u00e1nos rizik\u00f3faktorok (a\n diabetes fenn\u00e1ll\u00e1si ideje, t\u00edpusa, hemoglobin-A1c<\/jats:sub>-szint, hypertonia)\n chorioideavastags\u00e1ggal val\u00f3 korrel\u00e1ci\u00f3j\u00e1nak meghat\u00e1roz\u00e1sa.\n M\u00f3dszer:<\/jats:italic> Prospekt\u00edv keresztmetszeti vizsg\u00e1lat Swept Source\n DRI Triton optikaikoherencia-tomogr\u00e1fia seg\u00edts\u00e9g\u00e9vel. Macula- \u00e9s\n chorioideavastags\u00e1g-t\u00e9rk\u00e9pet k\u00e9sz\u00edtett\u00fcnk 60 diabeteses beteg 117 szem\u00e9r\u0151l.\n Kontrollcsoportk\u00e9nt 24 f\u0151 45 szem\u00e9t vizsg\u00e1ltuk. A chorioideavastags\u00e1g\n v\u00e1ltoz\u00e1s\u00e1nak a cukorbetegs\u00e9ggel, valamint a sziszt\u00e9m\u00e1s rizik\u00f3faktorokkal val\u00f3\n \u00f6sszef\u00fcgg\u00e9s\u00e9t elemezt\u00fck. A chorioideavastags\u00e1g \u00e9s a diabeteses retinopathia\n s\u00falyoss\u00e1ga (nincs, nonproliferat\u00edv\/proliferat\u00edv st\u00e1dium) k\u00f6z\u00f6tti kapcsolatot,\n valamint a panretinalis l\u00e9zerkezel\u00e9s hat\u00e1s\u00e1t is vizsg\u00e1ltuk.\n Eredm\u00e9nyek:<\/jats:italic> Cukorbetegekben szignifik\u00e1nsan alacsonyabb\n chorioideavastags\u00e1got tal\u00e1ltunk eg\u00e9szs\u00e9ges kontrollcsoporttal \u00f6sszehasonl\u00edtva\n (p<0,05). Az eg\u00e9sz beteganyagot vizsg\u00e1lva az \u00e9letkor (p<0,001) \u00e9s a\n hypertonia jelenl\u00e9te (p<0,05) szignifik\u00e1ns korrel\u00e1ci\u00f3t mutatott a chorioidea\n elv\u00e9konyod\u00e1s\u00e1val. A cukorbetegs\u00e9g fenn\u00e1ll\u00e1si ideje \u00e9s a chorioidea elv\u00e9konyod\u00e1sa\n k\u00f6z\u00f6tt szignifik\u00e1ns \u00f6sszef\u00fcgg\u00e9st mutattunk ki (p<0,05). A sziszt\u00e9m\u00e1s\n rizik\u00f3faktorokat t\u00f6bbv\u00e1ltoz\u00f3s modellben vizsg\u00e1lva a betegs\u00e9g fenn\u00e1ll\u00e1si ideje a\n chorioideavastags\u00e1g-cs\u00f6kken\u00e9s szignifik\u00e1ns prediktora maradt (\u03b2 \u20130,18, p =\n 0,02). Szignifik\u00e1nsan alacsonyabbnak tal\u00e1ltuk a chorioideavastags\u00e1got a\n proliferat\u00edv retinopathi\u00e1ban szenved\u0151 \u00e9s a panretinalis l\u00e9zerkezel\u00e9sen \u00e1tesett\n betegekben a nonproliferat\u00edv csoporttal \u00f6sszehasonl\u00edtva (p<0,05).\n K\u00f6vetkeztet\u00e9s:<\/jats:italic> Vizsg\u00e1latunk igazolta, hogy a sziszt\u00e9m\u00e1s\n rizik\u00f3faktorok (\u00e9letkor, hypertonia, a diabetes fenn\u00e1ll\u00e1si ideje) mellett a\n diabetes jelenl\u00e9te \u00e9s a diabeteses retinopathia progresszi\u00f3ja is hat\u00e1ssal van a\n chorioidea elv\u00e9konyod\u00e1s\u00e1ra. A tov\u00e1bbiakban kimutattuk, hogy panretinalis\n l\u00e9zerkezel\u00e9s hat\u00e1s\u00e1ra a chorioideavastags\u00e1g szignifik\u00e1ns cs\u00f6kken\u00e9se figyelhet\u0151\n meg. Orv Hetil. 2020; 161(35): 1475\u20131482.<\/jats:p>","DOI":"10.1556\/650.2020.31805","type":"journal-article","created":{"date-parts":[[2020,9,2]],"date-time":"2020-09-02T01:01:27Z","timestamp":1599008487000},"page":"1475-1482","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":2,"title":["A chorioidea vastags\u00e1g\u00e1nak v\u00e1ltoz\u00e1sa diabeteses betegekben"],"prefix":"10.1556","volume":"161","author":[{"given":"Hajnalka","family":"Horv\u00e1th","sequence":"first","affiliation":[{"name":"1 \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Szem\u00e9szeti Klinika, Semmelweis Egyetem, Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00f3nika","family":"Ecsedy","sequence":"additional","affiliation":[{"name":"1 \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Szem\u00e9szeti Klinika, Semmelweis Egyetem, Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ill\u00e9s","family":"Kov\u00e1cs","sequence":"additional","affiliation":[{"name":"1 \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Szem\u00e9szeti Klinika, Semmelweis Egyetem, Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00e1bor L\u00e1szl\u00f3","family":"S\u00e1ndor","sequence":"additional","affiliation":[{"name":"1 \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Szem\u00e9szeti Klinika, Semmelweis Egyetem, Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Klaudia","family":"Mall\u00e1r","sequence":"additional","affiliation":[{"name":"1 \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Szem\u00e9szeti Klinika, Semmelweis Egyetem, Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cec\u00edlia","family":"Czak\u00f3","sequence":"additional","affiliation":[{"name":"1 \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Szem\u00e9szeti Klinika, Semmelweis Egyetem, Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zolt\u00e1n Zsolt","family":"Nagy","sequence":"additional","affiliation":[{"name":"1 \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Szem\u00e9szeti Klinika, Semmelweis Egyetem, Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anik\u00f3","family":"Somogyi","sequence":"additional","affiliation":[{"name":"2 \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Belgy\u00f3gy\u00e1szati \u00e9s Hematol\u00f3giai Klinika, Semmelweis Egyetem, Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","container-title":["Orvosi Hetilap"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/650\/161\/35\/article-p1475.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/downloadpdf\/journals\/650\/161\/35\/article-p1475.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,11]],"date-time":"2021-10-11T01:13:12Z","timestamp":1633914792000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/view\/journals\/650\/161\/35\/article-p1475.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8]]},"references-count":0,"journal-issue":{"issue":"35"},"URL":"https:\/\/doi.org\/10.1556\/650.2020.31805","relation":{},"ISSN":["0030-6002","1788-6120"],"issn-type":[{"value":"0030-6002","type":"print"},{"value":"1788-6120","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8]]}}}