{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,31]],"date-time":"2023-10-31T14:10:55Z","timestamp":1698761455737},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"25","content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["Orv Hetil."],"published-print":{"date-parts":[[2020,6]]},"abstract":"Absztrakt: <\/jats:title>\n Az \u00faj koronav\u00edrus \u00e1ltal okozott COVID\u201319 t\u00fcd\u0151gyullad\u00e1ssal, heveny l\u00e9gz\u00e9si\n el\u00e9gtelens\u00e9ggel vagy ak\u00e1r szepszissel j\u00e1rhat. Azokn\u00e1l a betegekn\u00e9l alakul ki\n gyakrabban s\u00falyos \u00e1llapot, akik valamilyen kr\u00f3nikus alapbetegs\u00e9gben szenvednek.\n Cikk\u00fcnk c\u00e9lja felh\u00edvni a figyelmet azon esetekre, amelyek elemz\u00e9se seg\u00edthet a\n COVID\u201319-t\u00fcd\u0151gyullad\u00e1s lefoly\u00e1s\u00e1t \u00e9s mortalit\u00e1s\u00e1t befoly\u00e1sol\u00f3 faktorok\n felder\u00edt\u00e9s\u00e9ben. Id\u0151s beteg\u00fcnk anamn\u00e9zis\u00e9ben rectumexstirpatio szerepel\n intraoperat\u00edv reanim\u00e1ci\u00f3val. 2020 janu\u00e1rj\u00e1ban egy id\u0151ben igazol\u00f3dott colon\n ascendens adenocarcinoma, illetve pulmonalis embolia. Hathetes, ter\u00e1pi\u00e1s d\u00f3zis\u00fa,\n kis molekulat\u00f6meg\u0171 heparinos (LMWH-) kezel\u00e9st k\u00f6vet\u0151en elv\u00e9gezt\u00fck a daganatos\n szegment reszekci\u00f3j\u00e1t. Intraoperat\u00edv sikeres reanim\u00e1ci\u00f3 t\u00f6rt\u00e9nt. A m\u0171t\u00e9t ut\u00e1n 15\n nappal endoszk\u00f3posan nem csillap\u00edthat\u00f3, spriccel\u0151 anastomosisv\u00e9rz\u00e9s miatt akut\n jobb oldali hemicolectomi\u00e1t v\u00e9gezt\u00fcnk. Ezt k\u00f6vet\u0151en a l\u00e1zas \u00e1llapot h\u00e1tter\u00e9ben\n COVID\u201319 igazol\u00f3dott; t\u00fcneti kezel\u00e9s mellett a beteg l\u00e1ztalann\u00e1 v\u00e1lt. A\n tov\u00e1bbiakban anastomosisinsufficientia alakult ki, mely konzervat\u00edv ter\u00e1pia\n alkalmaz\u00e1sa mellett szint\u00e9n gy\u00f3gyult. H\u00e1rom negat\u00edv SARS-CoV-2-vizsg\u00e1lat ut\u00e1n\n beteg\u00fcnket emitt\u00e1ltuk. Figyelemre m\u00e9lt\u00f3, hogy beteg\u00fcnk preoperat\u00edv tart\u00f3s\n LMWH-kezel\u00e9sben r\u00e9szes\u00fclt; az akt\u00edv v\u00e9rz\u00e9s miatt gy\u00f3gyszerel\u00e9s\u00e9b\u0151l az\n angiotenzinkonvert\u00e1l\u00f3enzim (ACE)-g\u00e1tl\u00f3 elhagy\u00e1sra ker\u00fclt, majd ezt k\u00f6vet\u0151en\n SARS-CoV-infekci\u00f3 alakult ki, de multimorbidit\u00e1sa ellen\u00e9re is meggy\u00f3gyult. A\n colorectalis carcinom\u00e1k a lassan n\u00f6vekv\u0151 malignom\u00e1k k\u00f6z\u00e9 tartoznak ugyan, \u00e1m\n fontosnak tartjuk ezek megfelel\u0151 id\u0151ben t\u00f6rt\u00e9n\u0151 kezel\u00e9s\u00e9t, m\u00e9g s\u00falyos\n j\u00e1rv\u00e1ny\u00fcgyi helyzetben is. Nagy kih\u00edv\u00e1s el\u00e9 \u00e1ll\u00edt minden orvost a pand\u00e9mia alatt\n a betegek megfelel\u0151 ell\u00e1t\u00e1sa, de \u2013 mint eset\u00fcnk is p\u00e9ld\u00e1zza \u2013 sikeres lehet a\n multimorbid betegek seb\u00e9szeti ell\u00e1t\u00e1sa is. Tov\u00e1bbi k\u00f6vetkeztet\u00e9s\u00fcnk, hogy\n \u00e9rdemes lenne vizsg\u00e1lni a t\u00e1rsbetegs\u00e9gek kezel\u00e9s\u00e9re haszn\u00e1lt gy\u00f3gyszerek \u00e9s a\n SARS-CoV-2 k\u00f6z\u00f6tti azon interakci\u00f3kat, amelyek befoly\u00e1solhatj\u00e1k a\n COVID\u201319-t\u00fcd\u0151gyullad\u00e1s kimenetel\u00e9t. Orv Hetil. 2020; 161(25): 1059\u20131062.<\/jats:p>","DOI":"10.1556\/650.2020.31866","type":"journal-article","created":{"date-parts":[[2020,7,29]],"date-time":"2020-07-29T01:01:55Z","timestamp":1595984515000},"page":"1059-1062","update-policy":"http:\/\/dx.doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":2,"title":["Vastagb\u00e9ldaganat a koronav\u00edrusj\u00e1rv\u00e1ny idej\u00e9n \u2013 id\u0151s, multimorbid n\u0151beteg COVID\u201319-t\u00fcd\u0151gyullad\u00e1s\u00e1nak gy\u00f3gyul\u00e1sa"],"prefix":"10.1556","volume":"161","author":[{"given":"B\u00e1lint","family":"Pord\u00e1ny","sequence":"first","affiliation":[{"name":"\u00c1ltal\u00e1nos Seb\u00e9szeti Profil, Szent Imre Egyetemi Oktat\u00f3k\u00f3rh\u00e1z Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gy\u00f6rgy","family":"Herczeg","sequence":"additional","affiliation":[{"name":"\u00c1ltal\u00e1nos Seb\u00e9szeti Profil, Szent Imre Egyetemi Oktat\u00f3k\u00f3rh\u00e1z Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikl\u00f3s","family":"M\u00e1t\u00e9","sequence":"additional","affiliation":[{"name":"\u00c1ltal\u00e1nos Seb\u00e9szeti Profil, Szent Imre Egyetemi Oktat\u00f3k\u00f3rh\u00e1z Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","container-title":["Orvosi Hetilap"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/650\/161\/25\/article-p1059.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/downloadpdf\/journals\/650\/161\/25\/article-p1059.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,11]],"date-time":"2021-10-11T01:13:03Z","timestamp":1633914783000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/view\/journals\/650\/161\/25\/article-p1059.xml"}},"subtitle":["(A COVID\u201319-pand\u00e9mia orvosszakmai k\u00e9rd\u00e9sei)"],"short-title":[],"issued":{"date-parts":[[2020,6]]},"references-count":0,"journal-issue":{"issue":"25"},"URL":"https:\/\/doi.org\/10.1556\/650.2020.31866","relation":{},"ISSN":["0030-6002","1788-6120"],"issn-type":[{"value":"0030-6002","type":"print"},{"value":"1788-6120","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6]]}}}