{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,30]],"date-time":"2022-03-30T16:30:43Z","timestamp":1648657843790},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"42","license":[{"start":{"date-parts":[[2020,10,18]],"date-time":"2020-10-18T00:00:00Z","timestamp":1602979200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2020,10,18]]},"abstract":"<jats:title>Absztrakt: <\/jats:title>\n                <jats:p>A status epilepticus a m\u00e1sodik leggyakoribb, s\u00fcrg\u0151ss\u00e9gi kezel\u00e9st ig\u00e9nyl\u0151\n                    neurol\u00f3giai \u00e1llapot. Hal\u00e1loz\u00e1sa 15\u201325%. A \u201etime is brain\u201d elve a status\n                    epilepticus kezel\u00e9s\u00e9re is igaz: min\u00e9l kor\u00e1bban kezdj\u00fck a megfelel\u0151 kezel\u00e9st,\n                    ann\u00e1l nagyobb val\u00f3sz\u00edn\u0171s\u00e9ggel tudjuk meg\u00e1ll\u00edtani a progresszi\u00f3t. Magas szint\u0171\n                    evidenci\u00e1kon alapul\u00f3 kezel\u00e9si protokollal a status epilepticus progresszi\u00f3ja az\n                    esetek 75\u201390%-\u00e1ban megel\u0151zhet\u0151, az induk\u00e1lt k\u00f3ma \u00e9s a hal\u00e1los kimenetel\n                    elker\u00fclhet\u0151. A status epilepticus kezel\u00e9se akkor a legsikeresebb, ha m\u00e1r a korai\n                    szakban megkezdj\u00fck a parenteralis benzodiazepinter\u00e1pi\u00e1t: im. midazol\u00e1m (0,2\n                    mg\/tskg, max. 10 mg). Szabad v\u00e9na eset\u00e9n lehet v\u00e9n\u00e1san is adni a benzodiazepint\n                    (10 mg diazep\u00e1m iv). Ha az els\u0151 benzodiazepinbolusra nem reag\u00e1l a status\n                    epilepticus, \u00e1lland\u00f3sult (benzodiazepinrefrakter) status epilepticusr\u00f3l\n                    besz\u00e9l\u00fcnk. Ilyenkor a benzodiazepin ism\u00e9tl\u00e9s\u00e9vel p\u00e1rhuzamosan nem benzodiazepin\n                    t\u00edpus\u00fa, gyorsan hat\u00f3 v\u00e9n\u00e1s antiepileptikumot is adni kell: iv. valpro\u00e1t (40\n                    mg\/kg, max. 3000 mg, 10 perc alatt) vagy levetiracet\u00e1m (60 mg\/kg, max. 4500 mg,\n                    10 perc alatt) javasolt. Az 1 \u00f3r\u00e1n t\u00fal is tart\u00f3, sem benzodiazepinre, sem\n                    antiepileptikumra nem reag\u00e1l\u00f3, refrakter status epilepticust neurointenz\u00edv\n                    oszt\u00e1lyon, teljes narcosissal (induk\u00e1lt k\u00f3m\u00e1val) kell kezelni. Az induk\u00e1lt k\u00f3m\u00e1t\n                    gyors hat\u00e1s\u00fa anesztetikummal lehet el\u00e9rni, els\u0151sorban propofol\u2013midazol\u00e1m\n                    kombin\u00e1ci\u00f3val. Orv Hetil. 2020; 161(42): 1779\u20131786.<\/jats:p>","DOI":"10.1556\/650.2020.31908","type":"journal-article","created":{"date-parts":[[2020,10,21]],"date-time":"2020-10-21T01:02:18Z","timestamp":1603242138000},"page":"1779-1786","update-policy":"http:\/\/dx.doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":0,"title":["Status epilepticus 2020"],"prefix":"10.1556","volume":"161","author":[{"given":"J\u00f3zsef","family":"Janszky","sequence":"first","affiliation":[{"name":"1 \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Neurol\u00f3giai Klinika, P\u00e9csi Tudom\u00e1nyegyetem, P\u00e9cs, R\u00e9t u. 2., 7623"},{"name":"2 MTA\u2013PTE Klinikai Idegtudom\u00e1nyi K\u00e9palkot\u00f3 Kutat\u00f3csoport, P\u00e9cs"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Be\u00e1ta","family":"B\u00f3n\u00e9","sequence":"additional","affiliation":[{"name":"1 \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Neurol\u00f3giai Klinika, P\u00e9csi Tudom\u00e1nyegyetem, P\u00e9cs, R\u00e9t u. 2., 7623"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R\u00e9ka","family":"Horv\u00e1th","sequence":"additional","affiliation":[{"name":"1 \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Neurol\u00f3giai Klinika, P\u00e9csi Tudom\u00e1nyegyetem, P\u00e9cs, R\u00e9t u. 2., 7623"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zs\u00f3fia","family":"S\u00fct\u0151","sequence":"additional","affiliation":[{"name":"1 \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Neurol\u00f3giai Klinika, P\u00e9csi Tudom\u00e1nyegyetem, P\u00e9cs, R\u00e9t u. 2., 7623"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00e1szl\u00f3","family":"Szap\u00e1ry","sequence":"additional","affiliation":[{"name":"1 \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Neurol\u00f3giai Klinika, P\u00e9csi Tudom\u00e1nyegyetem, P\u00e9cs, R\u00e9t u. 2., 7623"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vera","family":"Juhos","sequence":"additional","affiliation":[{"name":"3 EPIHOPE Epilepszia K\u00f6zpont, Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00e1muel","family":"Komoly","sequence":"additional","affiliation":[{"name":"1 \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Neurol\u00f3giai Klinika, P\u00e9csi Tudom\u00e1nyegyetem, P\u00e9cs, R\u00e9t u. 2., 7623"},{"name":"2 MTA\u2013PTE Klinikai Idegtudom\u00e1nyi K\u00e9palkot\u00f3 Kutat\u00f3csoport, P\u00e9cs"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norbert","family":"Kov\u00e1cs","sequence":"additional","affiliation":[{"name":"1 \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Neurol\u00f3giai Klinika, P\u00e9csi Tudom\u00e1nyegyetem, P\u00e9cs, R\u00e9t u. 2., 7623"},{"name":"2 MTA\u2013PTE Klinikai Idegtudom\u00e1nyi K\u00e9palkot\u00f3 Kutat\u00f3csoport, P\u00e9cs"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","container-title":["Orvosi Hetilap"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/650\/161\/42\/article-p1779.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/downloadpdf\/journals\/650\/161\/42\/article-p1779.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,11]],"date-time":"2021-10-11T01:12:40Z","timestamp":1633914760000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/view\/journals\/650\/161\/42\/article-p1779.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,18]]},"references-count":0,"journal-issue":{"issue":"42"},"URL":"https:\/\/doi.org\/10.1556\/650.2020.31908","relation":{},"ISSN":["0030-6002","1788-6120"],"issn-type":[{"value":"0030-6002","type":"print"},{"value":"1788-6120","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10,18]]}}}