{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T18:23:58Z","timestamp":1781115838404,"version":"3.54.1"},"reference-count":50,"publisher":"Akademiai Kiado Zrt.","issue":"2","license":[{"start":{"date-parts":[[2021,1,10]],"date-time":"2021-01-10T00:00:00Z","timestamp":1610236800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2021,1,10]]},"abstract":"<jats:p><jats:bold>\u00d6sszefoglal\u00f3.<\/jats:bold> A sz\u00e1razszem-panaszok h\u00e1tter\u00e9ben gyakran \u00e1ll\n                    Meibom-mirigy-diszfunkci\u00f3, melynek felismer\u00e9se kiemelten fontos a hat\u00e9kony\n                    kezel\u00e9s \u00e9rdek\u00e9ben. A Meibom-mirigyek k\u00f3ros m\u0171k\u00f6d\u00e9se miatt a termelt lipid nem\n                    oszlik el megfelel\u0151en a szemfelsz\u00ednen, \u00edgy a k\u00f6nnyfilm p\u00e1rolg\u00e1sa fokoz\u00f3dik. A\n                    k\u00f6nnytermel\u00e9si zavar k\u00f6vetkezt\u00e9ben sz\u00e1razszem-panaszok alakulnak ki, melyek a\n                    hagyom\u00e1nyos k\u00f6nnyp\u00f3tl\u00f3 kezel\u00e9sre rendszerint csak \u00e1tmenetileg javulnak. A\n                    Meibom-mirigy-diszfunkci\u00f3t gyakran k\u00eds\u00e9ri a szemh\u00e9jsz\u00e9l\n                        <jats:italic>Demodex-<\/jats:italic>atka-fert\u0151z\u00e9se \u2013 az atka eradik\u00e1l\u00e1sa sz\u00fcks\u00e9ges a\n                    mirigyek m\u0171k\u00f6d\u00e9s\u00e9nek helyre\u00e1ll\u00edt\u00e1s\u00e1hoz \u00e9s ez\u00e1ltal a panaszok megsz\u00fcntet\u00e9s\u00e9hez. A\n                    Meibom-mirigy-diszfunkci\u00f3 a leggyakrabban enyhe form\u00e1ban jelentkezik; a ter\u00e1pia\n                    ilyenkor a beteg \u00e1ltal is elv\u00e9gezhet\u0151 szemh\u00e9jtiszt\u00edt\u00e1sb\u00f3l \u00e1ll, m\u00edg a gy\u00f3gyszeres\n                    kezel\u00e9s csak az el\u0151rehaladottabb, kifejezett gyullad\u00e1ssal j\u00e1r\u00f3 form\u00e1kban\n                    sz\u00fcks\u00e9ges. Az \u00f6sszefoglal\u00f3 \u00e1ttekinti a Meibom-mirigy-diszfunkci\u00f3 klinikai\n                    jeleivel \u00e9s kezel\u00e9s\u00e9vel kapcsolatos legfontosabb tudnival\u00f3kat, k\u00fcl\u00f6n\u00f6s\n                    tekintettel a <jats:italic>Demodex<\/jats:italic>-fert\u0151z\u00e9s felismer\u00e9s\u00e9re \u00e9s kezel\u00e9s\u00e9re\n                    vonatkoz\u00f3an. Orv Hetil. 2021; 162(2): 43\u201351.<\/jats:p>\n                <jats:p><jats:bold>Summary.<\/jats:bold> The onset of dry eye complaints is often a result of\n                    Meibomian gland dysfunction and its diagnosis is essential for effective\n                    treatment. In the case of Meibomian gland dysfunction, there is an increased\n                    evaporation of the tear film due to the abnormal secretion of lipids that cannot\n                    spread on the ocular surface. The treatment of dry eye complaints associated\n                    with Meibomian gland dysfunction with tear supplementation is usually\n                    ineffective and only results in an intermittent relief of complaints. Meibomian\n                    gland dysfunction is often associated with <jats:italic>Demodex<\/jats:italic> infestation\n                    of the eyelids, and eradicating the mites is essential to re-establish normal\n                    meibum production and thus, decreasing ocular complaints. In most cases,\n                    Meibomian gland dysfunction is mild, and the treatment of these forms is based\n                    on ocular hygiene performed by the patient, while only more advanced forms with\n                    inflammatory processes require pharmacologic treatment. This review summarizes\n                    the most important knowledge on the clinical signs and treatment of Meibomian\n                    gland dysfunction with particular attention to the diagnosis and treatment of\n                    ocular <jats:italic>Demodex<\/jats:italic> infection. Orv Hetil. 2021; 162(2): 43\u201351.<\/jats:p>","DOI":"10.1556\/650.2021.31958","type":"journal-article","created":{"date-parts":[[2021,3,30]],"date-time":"2021-03-30T12:09:37Z","timestamp":1617106177000},"page":"43-51","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":6,"title":["Meibom-mirigy-diszfunkci\u00f3 \u00e9s a sz\u00e1raz szem"],"prefix":"10.1556","volume":"162","author":[{"given":"Bal\u00e1zs","family":"Kov\u00e1cs","sequence":"first","affiliation":[{"name":"1 Kaposi M\u00f3r Megyei K\u00f3rh\u00e1z, Szem\u00e9szeti Oszt\u00e1ly, Kaposv\u00e1r"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bogl\u00e1rka","family":"L\u00e1ng","sequence":"additional","affiliation":[{"name":"2 P\u00e9csi Tudom\u00e1nyegyetem, Gy\u00f3gyszer\u00e9sztudom\u00e1nyi Kar, Gy\u00f3gyszertechnol\u00f3giai \u00e9s Biofarm\u00e1ciai Int\u00e9zet, P\u00e9cs"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Tak\u00e1csi-Nagy","sequence":"additional","affiliation":[{"name":"2 P\u00e9csi Tudom\u00e1nyegyetem, Gy\u00f3gyszer\u00e9sztudom\u00e1nyi Kar, Gy\u00f3gyszertechnol\u00f3giai \u00e9s Biofarm\u00e1ciai Int\u00e9zet, P\u00e9cs"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gy\u00f6rgyi","family":"Horv\u00e1th","sequence":"additional","affiliation":[{"name":"3 P\u00e9csi Tudom\u00e1nyegyetem, Gy\u00f3gyszer\u00e9sztudom\u00e1nyi Kar, Farmakogn\u00f3ziai Int\u00e9zet, P\u00e9cs"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cec\u00edlia","family":"Czak\u00f3","sequence":"additional","affiliation":[{"name":"4 Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Szem\u00e9szeti Klinika, Budapest, \u00dcll\u0151i \u00fat 26., 1085"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita","family":"Csorba","sequence":"additional","affiliation":[{"name":"4 Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Szem\u00e9szeti Klinika, Budapest, \u00dcll\u0151i \u00fat 26., 1085"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huba","family":"Kiss","sequence":"additional","affiliation":[{"name":"4 Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Szem\u00e9szeti Klinika, Budapest, \u00dcll\u0151i \u00fat 26., 1085"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ir\u00e9n","family":"Szalai","sequence":"additional","affiliation":[{"name":"4 Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Szem\u00e9szeti Klinika, Budapest, \u00dcll\u0151i \u00fat 26., 1085"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zolt\u00e1n Zsolt","family":"Nagy","sequence":"additional","affiliation":[{"name":"4 Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Szem\u00e9szeti Klinika, Budapest, \u00dcll\u0151i \u00fat 26., 1085"},{"name":"5 Semmelweis Egyetem, Eg\u00e9szs\u00e9gtudom\u00e1nyi Kar, Budapest"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ill\u00e9s","family":"Kov\u00e1cs","sequence":"additional","affiliation":[{"name":"4 Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Szem\u00e9szeti Klinika, Budapest, \u00dcll\u0151i \u00fat 26., 1085"},{"name":"5 Semmelweis Egyetem, Eg\u00e9szs\u00e9gtudom\u00e1nyi Kar, Budapest"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"ref0","doi-asserted-by":"publisher","first-page":"1938","DOI":"10.1167\/iovs.10-6997c","article-title":"The International Workshop on Meibomian Gland Dysfunction: report of the Subcommittee on Anatomy, Physiology, and Pathophysiology of the Meibomian Gland","volume":"52","author":"1 Knop","year":"2011","unstructured":"1 Knop E, Knop N, Millar T, et al. 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