{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T10:13:01Z","timestamp":1698833581066},"reference-count":19,"publisher":"Akademiai Kiado Zrt.","issue":"11","license":[{"start":{"date-parts":[[2021,3,14]],"date-time":"2021-03-14T00:00:00Z","timestamp":1615680000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2021,3,14]]},"abstract":"<jats:p><jats:bold>\u00d6sszefoglal\u00f3.<\/jats:bold> A Cronkhite\u2013Canada-szindr\u00f3ma egy extr\u00e9m ritka, nem\n                    \u00f6r\u00f6kl\u0151d\u0151, gyomor-b\u00e9l rendszeri polyposissal, feh\u00e9rjeveszt\u0151 enteropathi\u00e1val \u00e9s\n                    ectodermalis elv\u00e1ltoz\u00e1sokkal j\u00e1r\u00f3 megbeteged\u00e9s. A vil\u00e1gon eddig \u00f6sszesen\n                    k\u00f6r\u00fclbel\u00fcl 500 esetet jegyeztek fel. Az etiol\u00f3gia pontosan nem tiszt\u00e1zott,\n                    h\u00e1tter\u00e9ben els\u0151sorban autoimmun folyamatot felt\u00e9teleznek. A diagn\u00f3zis a p\u00e1ciens\n                    k\u00f3rt\u00f6rt\u00e9net\u00e9n, a fizik\u00e1lis vizsg\u00e1laton, az endoszk\u00f3pos k\u00e9pen \u00e9s a sz\u00f6vettani\n                    leleten alapul. A jelen k\u00f6zlem\u00e9nyben egy 71 \u00e9ves f\u00e9rfi beteg eset\u00e9t mutatjuk be.\n                    A klinikai k\u00e9p \u00e9s az elv\u00e9gzett vizsg\u00e1latok alapj\u00e1n a t\u00fcnetek h\u00e1tter\u00e9ben\n                    Cronkhite\u2013Canada-szindr\u00f3m\u00e1t igazoltunk, majd a szakirodalomban leggyakrabban\n                    alkalmazott kombin\u00e1lt protonpumpag\u00e1tl\u00f3, kortikoszteroid \u00e9s meszalazin ad\u00e1s\u00e1t\n                    vezett\u00fck be, illetve t\u00e1pl\u00e1l\u00e1ster\u00e1pi\u00e1t alkalmaztunk. Tudom\u00e1sunk szerint\n                    Cronkhite\u2013Canada-szindr\u00f3m\u00e1s beteg esete Magyarorsz\u00e1gon els\u0151k\u00e9nt ker\u00fcl\n                    ismertet\u00e9sre. Orv Hetil. 2021; 162(11): 432\u2013438.<\/jats:p>\n                <jats:p><jats:bold>Summary.<\/jats:bold> Cronkhite\u2013Canada syndrome is an extremely rare,\n                    noninherited disease, characterized by gastrointestinal polyposis,\n                    protein-losing enteropathy and ectodermal abnormalities. Approximately 500 cases\n                    have been reported worldwide. The aetiology is unknown, most probably autoimmune\n                    mechanisms may be involved. The diagnosis is based on patient history, physical\n                    examination, endoscopic findings and histology. Here we report the case of a\n                    71-year-old male, diagnosed with Cronkhite\u2013Canada syndrome. The treatment\n                    consisted of proton-pump inhibitor, corticosteroids, mesalazin and nutritional\n                    therapy. To the best of our knowledge, this is the first report of\n                    Cronkhite\u2013Canada syndrome in Hungary. Orv Hetil. 2021; 162(11): 432\u2013438.<\/jats:p>","DOI":"10.1556\/650.2021.32055","type":"journal-article","created":{"date-parts":[[2021,3,30]],"date-time":"2021-03-30T12:09:48Z","timestamp":1617106188000},"page":"432-438","update-policy":"http:\/\/dx.doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":1,"title":["Cronkhite\u2013Canada-szindr\u00f3ma"],"prefix":"10.1556","volume":"162","author":[{"given":"Anita","family":"Nagy","sequence":"first","affiliation":[{"name":"1 Szent Imre Egyetemi Oktat\u00f3k\u00f3rh\u00e1z, Gasztroenterol\u00f3gia Profil, Budapest, T\u00e9t\u00e9nyi \u00fat 12\u201316., 1115"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Levente","family":"T\u00f3th","sequence":"additional","affiliation":[{"name":"1 Szent Imre Egyetemi Oktat\u00f3k\u00f3rh\u00e1z, Gasztroenterol\u00f3gia Profil, Budapest, T\u00e9t\u00e9nyi \u00fat 12\u201316., 1115"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00e1nos","family":"Theisz","sequence":"additional","affiliation":[{"name":"1 Szent Imre Egyetemi Oktat\u00f3k\u00f3rh\u00e1z, Gasztroenterol\u00f3gia Profil, Budapest, T\u00e9t\u00e9nyi \u00fat 12\u201316., 1115"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N\u00e1ndor","family":"Bajk\u00f3","sequence":"additional","affiliation":[{"name":"2 Szent Imre Egyetemi Oktat\u00f3k\u00f3rh\u00e1z, K\u00e9palkot\u00f3 Diagnosztikai Oszt\u00e1ly, Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zs\u00f3fia","family":"Zolnai","sequence":"additional","affiliation":[{"name":"3 Szent Imre Egyetemi Oktat\u00f3k\u00f3rh\u00e1z, Patol\u00f3giai Oszt\u00e1ly, Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M\u00e1ria","family":"Varga","sequence":"additional","affiliation":[{"name":"4 Szent Imre Egyetemi Oktat\u00f3k\u00f3rh\u00e1z, Dietetikai Szolg\u00e1lat, Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iv\u00e1n","family":"Igaz","sequence":"additional","affiliation":[{"name":"1 Szent Imre Egyetemi Oktat\u00f3k\u00f3rh\u00e1z, Gasztroenterol\u00f3gia Profil, Budapest, T\u00e9t\u00e9nyi \u00fat 12\u201316., 1115"},{"name":"5 Szent Margit K\u00f3rh\u00e1z, Gasztroenterol\u00f3gia Oszt\u00e1ly, Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"ref0","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1038\/nrgastro.2010.112","article-title":"A case of Cronkhite-Canada syndrome presenting with adenomatous and inflammatory colon polyps","volume":"7","author":"1 Sweetser","year":"2010","unstructured":"1 Sweetser S, Alexander GL, Boardman LA. 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