{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T13:16:09Z","timestamp":1698844569414},"reference-count":23,"publisher":"Akademiai Kiado Zrt.","issue":"25","content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2021,6,20]]},"abstract":"<jats:p><jats:bold>\u00d6sszefoglal\u00f3.<\/jats:bold> A retropharyngealis nyirokcsom\u00f3\u00e1tt\u00e9tek incidenci\u00e1ja a\n                    primer fej-nyaki daganat lokaliz\u00e1ci\u00f3j\u00e1t\u00f3l f\u00fcgg. Leggyakrabban az el\u0151rehaladott\n                    vagy recid\u00edv nasopharynx-carcinom\u00e1k eset\u00e9n fordul el\u0151, de III\u2013IV. st\u00e1dium\u00fa oro-\n                    \u00e9s hypopharynxtumorok eset\u00e9n is megjelenhetnek. Non-nasopharyngealis primer\n                    tumorokn\u00e1l a manifeszt\u00e1ci\u00f3juk kedvez\u0151tlen prognosztikai faktornak tekinthet\u0151,\n                    melynek h\u00e1tter\u00e9ben a diagnosztikus neh\u00e9zs\u00e9g miatti k\u00e9s\u0151i detekt\u00e1l\u00e1s, a\n                    kifejezetten neh\u00e9z seb\u00e9szi elt\u00e1vol\u00edthat\u00f3s\u00e1g, valamint az agressz\u00edv biol\u00f3giai\n                    viselked\u00e9s \u00e1llhat. Az esetismertet\u00e9s\u00fcnkben bemutat\u00e1sra ker\u00fcl\u0151, 58 \u00e9ves\n                    beteg\u00fcnkn\u00e9l bal oldali el\u00fcls\u0151 sz\u00e1jfen\u00e9ki primer tumort diagnosztiz\u00e1ltunk azonos\n                    oldali nyaki \u00e9s retropharyngealis nyirokcsom\u00f3-metastasissal, mely a nemzetk\u00f6zi\n                    irodalom alapj\u00e1n extr\u00e9m rarit\u00e1s, incidenci\u00e1ja kevesebb mint 1%. A\n                    retropharyngealis nyirokcsom\u00f3k diagnosztik\u00e1j\u00e1ban a lokaliz\u00e1ci\u00f3 miatt a\n                    k\u00e9palkot\u00f3knak jut hangs\u00falyosabb szerep. Elhelyezked\u00e9s\u00fck nemcsak diagnosztikus,\n                    hanem seb\u00e9sztechnikai kih\u00edv\u00e1st is jelentenek az \u00e9letfontoss\u00e1g\u00fa anat\u00f3miai\n                    k\u00e9pletek k\u00f6zels\u00e9ge, illetve a sz\u0171k felt\u00e1r\u00e1si viszonyok miatt. Ilyenform\u00e1n ezek a\n                    m\u0171t\u00e9tek csak intenz\u00edv oszt\u00e1lyos h\u00e1tt\u00e9rrel \u00e9s kell\u0151 j\u00e1rtass\u00e1ggal rendelkez\u0151\n                    centrumokban v\u00e9gezhet\u0151k. Az alapvet\u0151en rossz progn\u00f3zist a korai diagn\u00f3zis \u00e9s a\n                    multimod\u00e1lis ter\u00e1pia kedvez\u0151en befoly\u00e1solja. Eset\u00fcnkben a komplex kezel\u00e9ssel\n                    (seb\u00e9szi ter\u00e1pia \u00e9s posztoperat\u00edv radiokemoter\u00e1pia) siker\u00fclt lokoregion\u00e1lis\n                    tumormentess\u00e9get el\u00e9rni, \u00e9s ezzel a teljes \u00e9s a betegs\u00e9gmentes t\u00fal\u00e9l\u00e9si id\u0151t\n                    n\u00f6velni. Orv Hetil. 2021; 162(25): 997\u20131003.<\/jats:p>\n                <jats:p><jats:bold>Summary.<\/jats:bold> The incidence of retropharyngeal lymph node metastasis\n                    depends on the localization of the primary head and neck cancer. Involved nodes\n                    are seen most commonly in cases of advanced or recurrent nasopharyngeal\n                    carcinoma, however, they might occur with stage III\u2013IV oro- and hypopharyngeal\n                    tumours. The involvement of retropharyngeal lymph nodes has been associated with\n                    poor outcome of non-nasopharyngeal primary tumours, which might be explained by\n                    the delayed diagnosis, the difficult surgical procedure in the retropharyngeal\n                    space, and the aggressive nature of the disease. Here we present the case of a\n                    58-year-old patient with an anterior oral cavity tumour on the left side with\n                    ipsilateral cervical lymph node and retropharyngeal lymph node metastases, which\n                    has been noted an extreme rarity in the literature with less than 1% incidence.\n                    Due to the localization of the retropharyngeal lymph nodes, the detection is\n                    based on imaging modalities. It represents a challenge for diagnosis and\n                    surgical treatment due to the close proximity of vital anatomical structures.\n                    Accordingly, these operations should only be performed in specialist surgical\n                    centres with intensive care units. The early diagnosis and the multimodality\n                    treatment might have a positive effect on the poor prognosis. In our case, we\n                    managed to achieve locoregional disease-free status with the complex treatment\n                    (surgical therapy and postoperative radiochemotherapy) and increase the overall\n                    and the disease-free survival. Orv Hetil. 2021; 162(25): 997\u20131003.<\/jats:p>","DOI":"10.1556\/650.2021.32063","type":"journal-article","created":{"date-parts":[[2021,8,31]],"date-time":"2021-08-31T10:05:26Z","timestamp":1630404326000},"page":"997-1003","update-policy":"http:\/\/dx.doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":0,"title":["A retropharyngealis nyirokcsom\u00f3\u00e1tt\u00e9tek klinikai jelent\u0151s\u00e9ge"],"prefix":"10.1556","volume":"162","author":[{"given":"M\u00f3nika","family":"R\u00e9v\u00e9sz","sequence":"first","affiliation":[{"name":"1 Osz\u00e1gos Onkol\u00f3giai Int\u00e9zet, Fej-Nyaki Daganatok Multidiszciplin\u00e1ris K\u00f6zpont, Budapest, R\u00e1th Gy\u00f6rgy u. 7\u20139., 1122"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferenc","family":"Oberna","sequence":"additional","affiliation":[{"name":"1 Osz\u00e1gos Onkol\u00f3giai Int\u00e9zet, Fej-Nyaki Daganatok Multidiszciplin\u00e1ris K\u00f6zpont, Budapest, R\u00e1th Gy\u00f6rgy u. 7\u20139., 1122"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c9va","family":"Remen\u00e1r","sequence":"additional","affiliation":[{"name":"1 Osz\u00e1gos Onkol\u00f3giai Int\u00e9zet, Fej-Nyaki Daganatok Multidiszciplin\u00e1ris K\u00f6zpont, Budapest, R\u00e1th Gy\u00f6rgy u. 7\u20139., 1122"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zolt\u00e1n","family":"Tak\u00e1csi-Nagy","sequence":"additional","affiliation":[{"name":"2 Orsz\u00e1gos Onkol\u00f3giai Int\u00e9zet, Sug\u00e1rter\u00e1pi\u00e1s K\u00f6zpont, Budapest"},{"name":"3 Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Onkol\u00f3giai Tansz\u00e9k, Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"ref0","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1016\/j.ijrobp.2006.02.027","article-title":"Prognostic influence of retropharyngeal lymph node metastasis in squamous cell carcinoma of the oropharynx","volume":"65","author":"1 Dirix","year":"2006","unstructured":"1 Dirix P, Nuyts S, Bussels B, et al. 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