{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T10:12:35Z","timestamp":1698833555176},"reference-count":19,"publisher":"Akademiai Kiado Zrt.","issue":"10","license":[{"start":{"date-parts":[[2021,3,7]],"date-time":"2021-03-07T00:00:00Z","timestamp":1615075200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2021,3,7]]},"abstract":"<jats:p><jats:bold>\u00d6sszefoglal\u00f3.<\/jats:bold> Sz\u00e1mos k\u00f6zlem\u00e9ny sz\u00fcletett arr\u00f3l, hogy a\n                    COVID\u201319-pneumoni\u00e1s betegek jelent\u0151s h\u00e1nyad\u00e1ban az art\u00e9ri\u00e1s parci\u00e1lis\n                    oxig\u00e9ntenzi\u00f3 kifejezetten alacsony, m\u00e9gsem jellemz\u0151 a dyspnoe, \u00e9s a\n                    pulzusoximetria sem mutat \u2013 a cs\u00f6kkent oxig\u00e9ntenzi\u00f3val ar\u00e1nyos \u2013 s\u00falyos\n                    hypoxaemi\u00e1t. A jelens\u00e9get \u201ehappy hypoxaemia\u201d n\u00e9ven eml\u00edtik. Ugyanakkor a\n                    l\u00e9gszomjr\u00f3l nem panaszkod\u00f3, de s\u00falyos alveolocapillaris O<jats:sub>2<\/jats:sub>-felv\u00e9teli\n                    zavarban szenved\u0151 COVID\u201319-pneumoni\u00e1s betegek a legkisebb fizikai megterhel\u00e9st\n                    sem t\u0171rik, \u00e9s \u00e1llapotuk gyorsan kritikuss\u00e1 v\u00e1lhat, teh\u00e1t a hypoxaemia m\u00e9rt\u00e9k\u00e9nek\n                    id\u0151ben val\u00f3 felismer\u00e9se kulcsk\u00e9rd\u00e9s. A jelen k\u00f6zlem\u00e9nyben egy ilyen eset r\u00f6vid\n                    ismertet\u00e9se ut\u00e1n \u00f6sszefoglaljuk a s\u00falyos, de t\u00fcnetmentes hypoxaemia h\u00e1tter\u00e9ben\n                    megh\u00faz\u00f3d\u00f3 \u00e9lettani okokat. Ezek k\u00f6z\u00f6tt szerepel a hypocapnia (respiratoricus\n                    alkalosis) is, mely alacsony oxig\u00e9ntenzi\u00f3 mellett is a hemoglobin viszonylag\n                    megtartott oxig\u00e9nszatur\u00e1ci\u00f3j\u00e1t eredm\u00e9nyezi. Ez\u00e9rt a mindennapi\n                    COVID\u201319-ell\u00e1t\u00e1sban a megism\u00e9telt art\u00e9ri\u00e1sv\u00e9rg\u00e1z-meghat\u00e1roz\u00e1sok jelent\u0151s\u00e9ge nem\n                    hangs\u00falyozhat\u00f3 el\u00e9gg\u00e9. Orv Hetil. 2021; 162(10): 362\u2013365.<\/jats:p>\n                <jats:p><jats:bold>Summary.<\/jats:bold> Many COVID-19 patients have very low arterial partial\n                    oxigen tension while severe dyspnoe does not develop. Pulse oxymetry indicates\n                    only moderate reduction of arterial O<jats:sub>2<\/jats:sub> saturation in these patients.\n                    The phenomenon is named \u201chappy hypoxaemia\u201d. Lack of (severe) dyspnoe and only\n                    moderately decreased O<jats:sub>2<\/jats:sub> saturation in severely impaired\n                    alveolo-capillary O<jats:sub>2<\/jats:sub> uptake may partially be explained by an\n                    increased oxygen affinity of hemoglobin in the presence of low arterial partial\n                    pressure of CO<jats:sub>2<\/jats:sub>. The latter results from increased alveolar\n                    ventilation, while low partial pressure of O<jats:sub>2<\/jats:sub> in COVID-19 patients\n                    reflects right-to-left shunting of pulmonary blood flow and\n                    ventilation-perfusion mismatch of the diseased lungs. While such patients may\n                    have mild complaints as related to the real impairment of alveolo-capillary\n                    oxygen exchange, severe hypoxaemia is a negative prognostic factor of outcome in\n                    this state where severe clinical deterioration may rapidly appear. The latter\n                    circumstance together with the unusual relationship of O<jats:sub>2<\/jats:sub> partial\n                    pressure and O<jats:sub>2<\/jats:sub> saturation of hemoglobin in COVID-19 emphasize the\n                    importance of repeated complete arterial blood gas analyses in these patients.\n                    Orv Hetil. 2021; 162(10): 362\u2013365.<\/jats:p>","DOI":"10.1556\/650.2021.32136","type":"journal-article","created":{"date-parts":[[2021,3,30]],"date-time":"2021-03-30T12:09:48Z","timestamp":1617106188000},"page":"362-365","update-policy":"http:\/\/dx.doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":1,"title":["S\u00falyos hypoxaemia l\u00e9gszomj n\u00e9lk\u00fcl COVID\u201319-pneumoni\u00e1ban"],"prefix":"10.1556","volume":"162","author":[{"given":"Gy\u00f6rgy","family":"Losonczy","sequence":"first","affiliation":[{"name":"1 Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Pulmonol\u00f3giai Klinika, Budapest, T\u00f6m\u0151 u. 25\u201329., 1083"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00f3zsef","family":"Luk\u00e1csovits","sequence":"additional","affiliation":[{"name":"1 Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Pulmonol\u00f3giai Klinika, Budapest, T\u00f6m\u0151 u. 25\u201329., 1083"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zolt\u00e1n","family":"S\u00fctt\u0151","sequence":"additional","affiliation":[{"name":"1 Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Pulmonol\u00f3giai Klinika, Budapest, T\u00f6m\u0151 u. 25\u201329., 1083"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e1s","family":"Lorx","sequence":"additional","affiliation":[{"name":"2 Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Aneszteziol\u00f3giai \u00e9s Intenz\u00edv Ter\u00e1pi\u00e1s Klinika, Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Veronika","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"1 Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Pulmonol\u00f3giai Klinika, Budapest, T\u00f6m\u0151 u. 25\u201329., 1083"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"ref0","doi-asserted-by":"publisher","first-page":"1239","DOI":"10.1001\/jama.2020.2648","article-title":"Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention","volume":"323","author":"1 Wu","year":"2020","unstructured":"1 Wu Z, McGoogan JM. 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