{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,12]],"date-time":"2024-06-12T10:28:42Z","timestamp":1718188122090},"reference-count":24,"publisher":"Akademiai Kiado Zrt.","issue":"44","license":[{"start":{"date-parts":[[2021,10,31]],"date-time":"2021-10-31T00:00:00Z","timestamp":1635638400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2021,10,31]]},"abstract":"<jats:p><jats:bold>\u00d6sszefoglal\u00f3.<\/jats:bold>\n                    <jats:italic>Bevezet\u00e9s:<\/jats:italic> A COVID\u201319-pand\u00e9mia kapcs\u00e1n sz\u00e1mos tanulm\u00e1ny\n                    vizsg\u00e1lta a t\u00fcnetek gyakoris\u00e1g\u00e1t \u00e9s a j\u00e1rv\u00e1nyterjed\u00e9s jellemz\u0151it gyermekkorban,\n                    kev\u00e9s azonban az alapell\u00e1t\u00e1s adatait \u00f6sszefoglal\u00f3 publik\u00e1ci\u00f3. K\u00f6zlem\u00e9ny\u00fcnkben 12\n                    h\u00e1zi gyermekorvosi praxis 545 SARS-CoV-2-fert\u0151z\u00f6tt beteg\u00e9nek adatait elemezt\u00fck a\n                    2. (n = 293) \u00e9s a 3. (n = 252) j\u00e1rv\u00e1nyhull\u00e1mban. <jats:italic>C\u00e9lkit\u0171z\u00e9s:<\/jats:italic> A\n                    gyermekkori fert\u0151z\u00e9sek t\u00fcnettan\u00e1nak \u00e9s epidemiol\u00f3giai jellemz\u0151inek\n                    \u00f6sszehasonl\u00edt\u00e1sa korcsoportok \u00e9s j\u00e1rv\u00e1nyhull\u00e1mok k\u00f6z\u00f6tt.\n                        <jats:italic>M\u00f3dszer:<\/jats:italic> Valamennyi alapell\u00e1t\u00f3 praxis egys\u00e9ges retrospekt\u00edv\n                    adatgy\u0171jt\u00e9st v\u00e9gzett ugyanazon param\u00e9terek regisztr\u00e1l\u00e1s\u00e1val.\n                        <jats:italic>Eredm\u00e9nyek:<\/jats:italic> A 10 \u00e9v alatti betegekben a l\u00e1z, a n\u00e1tha \u00e9s a\n                    k\u00f6h\u00f6g\u00e9s domin\u00e1lt (30\u201350%), m\u00edg a 10 \u00e9v felettiekben magas ar\u00e1nyban\n                    regisztr\u00e1ltunk \u00e1ltal\u00e1nos t\u00fcneteket is (30\u201340% fejf\u00e1j\u00e1s, gyenges\u00e9g,\n                    szagl\u00e1szavar). A 2. hull\u00e1mban a 11\u201318 \u00e9vesek (68%), a 3. hull\u00e1mban a 0\u201310 \u00e9vesek\n                    (53%) voltak t\u00f6bbs\u00e9gben. A 3. hull\u00e1mban szignifik\u00e1nsan emelkedett a l\u00e9g\u00fati\n                    t\u00fcnetek el\u0151fordul\u00e1sa, az \u00e1ltal\u00e1nos t\u00fcnetek gyakoris\u00e1ga jelent\u0151sen cs\u00f6kkent, \u00e9s\n                    szignifik\u00e1nsan n\u0151tt a csal\u00e1don bel\u00fcli expoz\u00edci\u00f3 ar\u00e1nya (36% <jats:italic>vs.<\/jats:italic>\n                    58%) a 2. hull\u00e1mmal \u00f6sszehasonl\u00edtva. A gyermekr\u0151l csal\u00e1dtagra t\u00f6rt\u00e9n\u0151\n                    tov\u00e1bbterjed\u00e9s 24% \u00e9s 16% volt a k\u00e9t j\u00e1rv\u00e1nyhull\u00e1mban, \u00e9s m\u00e9rt\u00e9k\u00e9t az \u00e9letkor\n                    befoly\u00e1solta. <jats:italic>Megbesz\u00e9l\u00e9s:<\/jats:italic> A klinikai k\u00e9p az \u00e9letkorral \u00e9s a\n                    felt\u00e9telezett v\u00edrusvari\u00e1nssal mutatott \u00f6sszef\u00fcgg\u00e9st: 10 \u00e9v alatt a l\u00e9g\u00fati\n                    t\u00fcnetek domin\u00e1ltak, 10 \u00e9v felett szignifik\u00e1nsan t\u00f6bb \u00e1ltal\u00e1nos t\u00fcnetet\n                    regisztr\u00e1ltunk a 0\u201310 \u00e9vesekhez k\u00e9pest. A 3. j\u00e1rv\u00e1nyhull\u00e1mban az alfa-vari\u00e1ns\n                    terjed\u00e9s\u00e9vel gyakoribb\u00e1 v\u00e1ltak a l\u00e9g\u00fati t\u00fcnetek, az iskolabez\u00e1r\u00e1sok\n                    k\u00f6vetkezt\u00e9ben megv\u00e1ltozott az \u00e9letkori megoszl\u00e1s, \u00e9s megemelkedett a csal\u00e1di\n                    expoz\u00edci\u00f3 okozta fert\u0151z\u00e9sek ar\u00e1nya. A fert\u0151z\u00e9s tov\u00e1bbad\u00e1sa h\u00e1ztart\u00e1son bel\u00fcl\n                    mindk\u00e9t hull\u00e1mban alacsony maradt. <jats:italic>K\u00f6vetkeztet\u00e9s:<\/jats:italic> A COVID\u201319\n                    klinikai megjelen\u00e9s\u00e9t \u00e9s terjed\u00e9si jellemz\u0151it jelent\u0151sen befoly\u00e1solta az\n                    \u00e9rintett gyermekpopul\u00e1ci\u00f3 \u00e9letkori \u00f6sszet\u00e9tele, a cirkul\u00e1l\u00f3 v\u00edrusvari\u00e1ns \u00e9s az\n                    aktu\u00e1lis korl\u00e1toz\u00f3 int\u00e9zked\u00e9sek. Orv Hetil. 2021; 162(44): 1751\u20131760.<\/jats:p>\n                <jats:p><jats:bold>Summary.<\/jats:bold>\n                    <jats:italic>Introduction:<\/jats:italic> During the COVID-19 pandemic, a large number of\n                    publications examined the frequency of symptoms and the mode of transmission in\n                    childhood but only a few community-based studies have been published. In our\n                    paper, 545 pediatric COVID-19 patients\u2019 data were collected by 12 primary care\n                    pediatricians in the second (n = 293) and third (n = 252) waves of the pandemic.\n                        <jats:italic>Objective:<\/jats:italic> To compare the frequency of symptoms and\n                    household transmission in different age groups and between the two waves.\n                        <jats:italic>Method:<\/jats:italic> Patients\u2019 data and disease characteristics were\n                    recorded retrospectively in the same manner by all participating pediatricians.\n                        <jats:italic>Results:<\/jats:italic> In patients of &lt;10 years of age, fever,\n                    rhinorrhea and cough were registered the most frequently (30\u201350%), in contrast\n                    to patients of &gt;10 years, where high frequency of general symptoms was found\n                    (30\u201340% headache, weakness, anosmia). In the third wave, the ratio of the age\n                    group 11\u201318 years declined from 68% to 47%, the frequency of respiratory\n                    symptoms increased significantly, while the ratio of general symptoms decreased.\n                    Household exposition was more frequent in the third wave (36%\n                        <jats:italic>vs.<\/jats:italic> 58%), while the transmission rate from children to\n                    family members was 24% and 16%, respectively, and it varied with age.\n                        <jats:italic>Discussion:<\/jats:italic> Clinical manifestation showed relation to age\n                    and virus variant: the older age associated with higher frequency of general\n                    symptoms and the spread of the alpha variant led to the predominance of\n                    respiratory symptoms over general complaints. Prolonged school closures affected\n                    the age distribution and increased the frequency of household exposition.\n                    Secondary household transmission remained low. <jats:italic>Conclusion:<\/jats:italic>\n                    Clinical and epidemiological characteristics of pediatric COVID-19 disease were\n                    highly influenced by age, dominant virus variant and mitigation measures. Orv\n                    Hetil. 2021; 162(44): 1751\u20131760.<\/jats:p>","DOI":"10.1556\/650.2021.32360","type":"journal-article","created":{"date-parts":[[2021,12,13]],"date-time":"2021-12-13T13:24:08Z","timestamp":1639401848000},"page":"1751-1760","update-policy":"http:\/\/dx.doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":3,"title":["Az alapell\u00e1t\u00e1sban kezelt COVID\u201319-fert\u0151z\u00f6tt gyermekek t\u00fcnettani \u00e9s epidemiol\u00f3giai jellemz\u0151i"],"prefix":"10.1556","volume":"162","author":[{"given":"\u00c9va","family":"Kar\u00e1szi","sequence":"first","affiliation":[{"name":"Budapest F\u0151v\u00e1ros XXII. ker\u00fclet \u2013 Budafok-T\u00e9t\u00e9ny \u00d6nkorm\u00e1nyzata, 3. sz. h\u00e1zi gyermekorvosi k\u00f6rzet, Budapest, K\u00e1ldor Adolf u. 3\u20135., 1221"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Be\u00e1ta","family":"Onoz\u00f3","sequence":"additional","affiliation":[{"name":"Miskolc Megyei Jog\u00fa V\u00e1ros \u00d6nkorm\u00e1nyzata, 32. sz. h\u00e1zi gyermekorvosi k\u00f6rzet, Miskolc"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adrienn","family":"S\u00fct\u0151","sequence":"additional","affiliation":[{"name":"P\u00e1ty K\u00f6zs\u00e9g \u00d6nkorm\u00e1nyzata, bet\u00f6ltetlen 2. sz. h\u00e1zi gyermekorvosi k\u00f6rzet (helyettes\u00edt\u00e9ssel ell\u00e1tott), P\u00e1ty"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katalin","family":"Kutas","sequence":"additional","affiliation":[{"name":"Budapest F\u0151v\u00e1ros XI. ker\u00fclet \u2013 \u00dajbuda \u00d6nkorm\u00e1nyzata, 17. sz. h\u00e1zi gyermekorvosi k\u00f6rzet, Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Be\u00e1ta","family":"Szal\u00f3czi","sequence":"additional","affiliation":[{"name":"Budapest F\u0151v\u00e1ros I. ker\u00fclet \u2013 Budav\u00e1ri \u00d6nkorm\u00e1nyzat, Markovits utcai h\u00e1zi gyermekorvosi rendel\u0151, Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melinda","family":"Laczkovszki","sequence":"additional","affiliation":[{"name":"Budapest F\u0151v\u00e1ros XXII. ker\u00fclet \u2013 Budafok-T\u00e9t\u00e9ny \u00d6nkorm\u00e1nyzata, 1. sz. h\u00e1zi gyermekorvosi k\u00f6rzet, Budapest"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriella","family":"Demeter","sequence":"additional","affiliation":[{"name":"Budapest F\u0151v\u00e1ros XVI. 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