{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,26]],"date-time":"2023-10-26T17:03:09Z","timestamp":1698339789373},"reference-count":27,"publisher":"Akademiai Kiado Zrt.","issue":"13","license":[{"start":{"date-parts":[[2022,3,27]],"date-time":"2022-03-27T00:00:00Z","timestamp":1648339200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2022,3,27]]},"abstract":"<jats:p><jats:bold>\u00d6sszefoglal\u00f3.<\/jats:bold>\n                    <jats:italic>Bevezet\u00e9s \u00e9s c\u00e9lkit\u0171z\u00e9s:<\/jats:italic> A gingivahyperplasia a\n                    kalciumcsatorna-blokkol\u00f3 gy\u00f3gyszerek gyakori mell\u00e9khat\u00e1sa. Eredm\u00e9nyeink\n                    k\u00f6zl\u00e9s\u00e9nek c\u00e9lja, hogy bemutassuk, seb\u00e9szi ter\u00e1pia n\u00e9lk\u00fcl, megfelel\u0151 egy\u00e9ni\n                    sz\u00e1jhigi\u00e9nia kialak\u00edt\u00e1s\u00e1val \u00e9s nem seb\u00e9szi parodontalis ter\u00e1pi\u00e1val milyen\n                    eredm\u00e9nyt tudunk el\u00e9rni az \u00ednymegnagyobbod\u00e1s kezel\u00e9se sor\u00e1n.\n                        <jats:italic>M\u00f3dszer:<\/jats:italic> A Szegedi Tudom\u00e1nyegyetem Fogorvostudom\u00e1nyi\n                    Kar\u00e1nak Parodontol\u00f3giai Tansz\u00e9k\u00e9n 2015 \u00e9s 2019 k\u00f6z\u00f6tt 10 \u2013 7 n\u0151 \u00e9s 3 f\u00e9rfi,\n                    \u00e1tlag\u00e9letkoruk 56 \u00e9v (50\u201369 \u00e9v) volt \u2013, kalciumcsatorna-blokkol\u00f3 gy\u00f3gyszer\n                    szed\u00e9se sor\u00e1n kialakul\u00f3, Grade III. \u00ednyhyperplasi\u00e1ban szenved\u0151 p\u00e1ciens kezel\u00e9s\u00e9t\n                    v\u00e9gezt\u00fck konzervat\u00edv parodontalis m\u00f3dszerekkel, a gy\u00f3gyszercsere mell\u0151z\u00e9s\u00e9vel. A\n                    legfontosabb parodontalis \u00e9rt\u00e9keket r\u00f6gz\u00edtett\u00fck, a tasakm\u00e9lys\u00e9g, a v\u00e9rz\u00e9si\n                    index, a plakkindex \u00e9s a fogmozgathat\u00f3s\u00e1g \u00e9rt\u00e9keit \u00f6sszegezt\u00fck vizsg\u00e1latunkban.\n                    A parodontium destrukci\u00f3ja m\u00e9rt\u00e9k\u00e9nek meg\u00e1llap\u00edt\u00e1s\u00e1hoz ortopantomogram \u00e9s\n                    periapicalis r\u00f6ntgenfelv\u00e9teleket \u00e9rt\u00e9kelt\u00fcnk. <jats:italic>Eredm\u00e9nyek:<\/jats:italic>\n                    Minden parodontol\u00f3giai param\u00e9terben jelent\u0151s javul\u00e1st tapasztaltunk. A nem\n                    seb\u00e9szi parodontalis ter\u00e1pia eredm\u00e9nyek\u00e9nt megsz\u0171nt az elv\u00e1ltoz\u00e1s mind a 10\n                    betegn\u00e9l, \u00e9s a szigor\u00fa fenntart\u00f3 ter\u00e1pi\u00e1nak is k\u00f6sz\u00f6nhet\u0151en nem is \u00fajult ki.\n                        <jats:italic>K\u00f6vetkeztet\u00e9s:<\/jats:italic> A nem seb\u00e9szi ter\u00e1pia alkalmasnak bizonyult\n                    a s\u00falyos gingivahyperplasia definit\u00edv kezel\u00e9s\u00e9re, ha az gingivitis vagy enyhe \u00e9s\n                    k\u00f6z\u00e9ps\u00falyos parodontitis talaj\u00e1n alakult ki. Arra is k\u00f6vetkeztethet\u00fcnk az\n                    eredm\u00e9nyeinkb\u0151l, hogy a gy\u00f3gyszeres ter\u00e1pia megkezd\u00e9se el\u0151tt vagy azzal\n                    p\u00e1rhuzamosan parodontol\u00f3giai ter\u00e1pi\u00e1ban r\u00e9szes\u00fcl\u0151 p\u00e1ciensek nagy r\u00e9sz\u00e9n\u00e9l a\n                    gingivahyperplasia \u2013 s ezzel a hossz\u00fa ideig tart\u00f3, dr\u00e1ga kezel\u00e9s \u2013 megel\u0151zhet\u0151\n                    lenne. Orv Hetil. 2022; 163(13): 506\u2013512.<\/jats:p>\n                <jats:p><jats:bold>Summary.<\/jats:bold>\n                    <jats:italic>Introduction and objective:<\/jats:italic> Gingival overgrowth is an adverse\n                    drug reaction in patients on long-term calcium channel blocker therapy. The aim\n                    of this study was to assess the efficacy of non-surgical pocket therapy in\n                    patients suffering from Grade III drug-related gingival overgrowth.\n                        <jats:italic>Method:<\/jats:italic> 10 (7 female and 3 male) patients (age between\n                    50\u201369 years) diagnosed with severe, Grade III gingival overgrowth were treated\n                    in our department. Non-surgical periodontal therapy consists of improving of\n                    individual oral hygiene, scaling, polishing and subgingival mechanical\n                    debridement instrumentation. The main periodontal parameters (probing pocket\n                    depth, bleeding index, plaque index and mobility) were scored in this study.\n                    Bone loss was evaluated by orthopantomograms and periapical radiographs. Calcium\n                    channel blockers have not been replaced by any other medications during the\n                    whole course of periodontal treatment. <jats:italic>Results:<\/jats:italic> Compared with\n                    baseline parameters, all scores improved after therapy. All patients showed\n                    decrease in the average probing pocket depth, deepest probing pocket depth,\n                    bleeding scores, plaque scores and tooth mobility. None of the patients needed\n                    further surgical treatment. In our followed-up patients, recurrence of gingival\n                    overgrowth has not been observed during the two-year meticulous supportive\n                    periodontal care in the patient group. <jats:italic>Conclusion:<\/jats:italic> Non-surgical\n                    periodontal treatment can be a potential definitive therapy in Grade III\n                    gingival overgrowth associated with gingivitis or moderate periodontitis.\n                    Periodontal screening and treatment before or simultaneously with the\n                    administration of calcium channel blockers can prevent the gingival enlargement\n                    in the majority of patient. These results outline the importance of the\n                    successful cause related periodontal therapy, started before or simultaneously\n                    with the administration of anithypertensive medications and in this way a series\n                    of further expensive therapies could be anticipated. Orv Hetil. 2022; 163(13):\n                    506\u2013512.<\/jats:p>","DOI":"10.1556\/650.2022.32385","type":"journal-article","created":{"date-parts":[[2022,11,18]],"date-time":"2022-11-18T10:58:49Z","timestamp":1668769129000},"page":"506-512","update-policy":"http:\/\/dx.doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":1,"title":["A kalciumcsatorna-blokkol\u00f3 gy\u00f3gyszerek \u00e1ltal induk\u00e1lt s\u00falyos gingivahyperplasia konzervat\u00edv kezel\u00e9se \u00e9s megel\u0151z\u00e9s\u00e9nek lehet\u0151s\u00e9gei"],"prefix":"10.1556","volume":"163","author":[{"given":"\u00c1gnes","family":"Cseke","sequence":"first","affiliation":[{"name":"Szegedi Tudom\u00e1nyegyetem, Fogorvostudom\u00e1nyi Kar, Parodontol\u00f3giai Tansz\u00e9k Szeged Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Filep","sequence":"additional","affiliation":[{"name":"Szegedi Tudom\u00e1nyegyetem, Fogorvostudom\u00e1nyi Kar, Parodontol\u00f3giai Tansz\u00e9k Szeged Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bence","family":"Kar\u00e1csonyi","sequence":"additional","affiliation":[{"name":"Szegedi Tudom\u00e1nyegyetem, Fogorvostudom\u00e1nyi Kar, Parodontol\u00f3giai Tansz\u00e9k Szeged Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P\u00e9ter","family":"V\u00e1lyi","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, Fogorvostudom\u00e1nyi Kar, Or\u00e1lis Diagnosztikai Tansz\u00e9k Budapest, Szentkir\u00e1lyi u. 47., 1088 Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"1 Peres MA, Macpherson LM, Weyant RJ, et al. 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