{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,26]],"date-time":"2024-07-26T14:30:28Z","timestamp":1722004228263},"reference-count":28,"publisher":"Akademiai Kiado Zrt.","issue":"20","content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2022,5,15]]},"abstract":"<jats:p><jats:italic>Bevezete\u0301s:<\/jats:italic> A gerinc intervertebralis discusainak\n                    magass\u00e1gcs\u00f6kken\u00e9se kiv\u00e1ltotta szegment\u00e1lis instabilit\u00e1s a feln\u0151tt lakoss\u00e1g\n                    70\u201380%-\u00e1t \u00e9rint\u0151 kr\u00f3nikus der\u00e9kf\u00e1j\u00e1s egyik legf\u0151bb oka. A magass\u00e1gcs\u00f6kken\u00e9s a\n                    porckorong f\u00fcgg\u0151leges kompresszi\u00f3s t\u00falterhel\u00e9se \u00e1ltal kiv\u00e1ltott folyad\u00e9kveszt\u00e9s\n                    induk\u00e1lta degenerat\u00edv elv\u00e1ltoz\u00e1sok k\u00f6vetkezm\u00e9nye.\n                        <jats:italic>Ce\u0301lkitu\u030bze\u0301s:<\/jats:italic> El\u0151zetes tanulm\u00e1nyt v\u00e9gezt\u00fcnk annak\n                    meg\u00e1llap\u00edt\u00e1s\u00e1ra, hogy a t\u00falterhel\u00e9sb\u0151l ad\u00f3d\u00f3 discusdegener\u00e1ci\u00f3 meg\u00e1ll\u00edthat\u00f3-e.\n                    Hipot\u00e9zis\u00fcnk az volt, hogy h\u00e1ts\u00f3 felt\u00e1r\u00e1sb\u00f3l v\u00e9gzett f\u00fazi\u00f3s m\u0171t\u00e9t sor\u00e1n\n                    distracti\u00f3val a discusokra hat\u00f3 nyom\u00e1s cs\u00f6kkenthet\u0151, a discusdegener\u00e1ci\u00f3\n                    meg\u00e1ll\u00edthat\u00f3, \u00e9s tal\u00e1n a porckorong m\u0171k\u00f6d\u00e9se helyre\u00e1ll\u00edthat\u00f3.\n                        <jats:italic>Mo\u0301dszerek:<\/jats:italic> A discusok \u00e1llapot\u00e1nak jellemz\u00e9s\u00e9re azok k\u00f6t\u00f6tt\n                    v\u00edztartalm\u00e1nak, ezen kereszt\u00fcl a rugalmass\u00e1guknak a biztos\u00edt\u00e1s\u00e1\u00e9rt felel\u0151s\n                    gl\u00fck\u00f3zaminoglik\u00e1n-tartalom meghat\u00e1roz\u00e1s\u00e1t haszn\u00e1ltuk. A gadol\u00ednium\n                    kontrasztanyag haszn\u00e1lata MRI sor\u00e1n (dGEMRIC) elfogadott m\u00f3dszer az\n                    intervertebralis discus gl\u00fck\u00f3zaminoglik\u00e1n-tartalm\u00e1nak meghat\u00e1roz\u00e1s\u00e1ra, mivel a\n                    felsz\u00edv\u00f3dott kontrasztanyag koncentr\u00e1ci\u00f3ja ford\u00edtottan ar\u00e1nyos a csigolyak\u00f6zi\n                    porckorongokban l\u00e9v\u0151 gl\u00fck\u00f3zaminoglik\u00e1nok mennyis\u00e9g\u00e9vel. Vizsg\u00e1ltuk pre-,\n                    posztoperat\u00edv dGEMRIC-adatok mellett a discus magass\u00e1g\u00e1t, az \u00e1gy\u00e9ki lordosist, a\n                    vizu\u00e1lis anal\u00f3g f\u00e1jdalomsk\u00e1l\u00e1t \u00e9s az Oswestry Rokkants\u00e1gi Indexet.\n                        <jats:italic>Eredme\u0301nyek:<\/jats:italic> Minden betegn\u00e9l szegment\u00e1lis instabilit\u00e1s\n                    miatt az \u00e9rintett szegmentum h\u00e1ts\u00f3 distracti\u00f3j\u00e1t k\u00f6vet\u0151 monoszegment\u00e1lis f\u00fazi\u00f3\n                    t\u00f6rt\u00e9nt. A m\u0171t\u00e9tek sor\u00e1n az \u00e1gy\u00e9ki lordosis a h\u00e1ts\u00f3 distractio ellen\u00e9re sem\n                    cs\u00f6kkent. A discusok magass\u00e1ga \u00e1tlagosan 3 mm-rel n\u0151tt, a f\u00e1jdalom cs\u00f6kkent, \u00e9s\n                    az Oswestry Rokkants\u00e1gi Index javul\u00e1st mutatott. A dGEMRIC-vizsg\u00e1latokban a\n                    m\u0171t\u00e9t el\u0151tt a porckorongokban \u00e1tlagosan 309,18 egys\u00e9g\/cm<jats:sup>2<\/jats:sup> gadol\u00ednium\n                    halmoz\u00f3dott fel, mely posztoperat\u00edve 174,43 egys\u00e9g\/cm<jats:sup>2<\/jats:sup>-re cs\u00f6kkent.\n                    Minden v\u00e1ltoz\u00e1s szignifik\u00e1ns volt p = 0,05 szignifikanciaszint mellett.\n                        <jats:italic>Ko\u0308vetkeztete\u0301s:<\/jats:italic> El\u0151zetes eredm\u00e9nyeink tendenci\u00e1ja azt\n                    sugallja, hogy a porckorongok magass\u00e1g\u00e1nak n\u00f6vel\u00e9s\u00e9vel cs\u00f6kkenthet\u0151 a\n                    porckorongokban a hidrosztatikus nyom\u00e1s; ez a gl\u00fck\u00f3zaminoglik\u00e1nok mennyis\u00e9g\u00e9nek\n                    n\u00f6veked\u00e9s\u00e9t eredm\u00e9nyezi, ami meg\u00e1ll\u00edthatja a discusok degener\u00e1ci\u00f3j\u00e1t, \u00e9s\n                    elind\u00edthat regener\u00e1ci\u00f3s folyamatokat is. Orv Hetil. 2022; 163(20): 789\u2013796.<\/jats:p>","DOI":"10.1556\/650.2022.32462","type":"journal-article","created":{"date-parts":[[2022,11,18]],"date-time":"2022-11-18T13:04:20Z","timestamp":1668776660000},"page":"789-796","update-policy":"http:\/\/dx.doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":1,"title":["Van-e es\u00e9ly az intervertebralis discusok regener\u00e1ci\u00f3j\u00e1ra?"],"prefix":"10.1556","volume":"163","author":[{"given":"Dragos","family":"Schiopu","sequence":"first","affiliation":[{"name":"Service d\u2019Orthop\u00e9die et Traumatologie, Centre Hospitalier Universitaire \u2013 Brugmann, Universit\u00e9 Libre de Bruxelles Place Van Gehuchten 4., Bruxelles 1020 Belgique"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arnaud","family":"Devriendt","sequence":"additional","affiliation":[{"name":"D\u00e9partement d\u2019Imagerie M\u00e9dicale, Centre Hospitalier Universitaire \u2013 Brugmann, Universit\u00e9 Libre de Bruxelles Bruxelles Belgique"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piet","family":"Reynders","sequence":"additional","affiliation":[{"name":"Service d\u2019Orthop\u00e9die et Traumatologie, Centre Hospitalier Universitaire \u2013 Brugmann, Universit\u00e9 Libre de Bruxelles Place Van Gehuchten 4., Bruxelles 1020 Belgique"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. 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