{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,20]],"date-time":"2026-01-20T06:19:12Z","timestamp":1768889952822,"version":"3.49.0"},"reference-count":23,"publisher":"Akademiai Kiado Zrt.","issue":"21","license":[{"start":{"date-parts":[[2022,5,22]],"date-time":"2022-05-22T00:00:00Z","timestamp":1653177600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2022,5,22]]},"abstract":"<jats:p><jats:italic>Bevezet\u00e9s \u00e9s c\u00e9lkit\u0171z\u00e9s:<\/jats:italic> Az otitis media suppurativa chronica\n                    cholesteatomatosa seb\u00e9szet\u00e9ben a mastoidobliter\u00e1ci\u00f3val v\u00e9gzett megold\u00e1s egyes\u00edti\n                    a nyitott \u00e9s a z\u00e1rt technik\u00e1val v\u00e9gzett m\u0171t\u00e9tek el\u0151nyeit. \u00d6sszehasonl\u00edt\u00f3\n                    prospekt\u00edv klinikai tanulm\u00e1nyunkban a csontporral \u00e9s a BonAlive<jats:sup>\u00ae<\/jats:sup>\n                    (S53P4) bioakt\u00edv \u00fcveggranul\u00e1tummal v\u00e9gzett mastoidobliter\u00e1ci\u00f3s m\u0171t\u00e9teinkkel\n                    szerzett tapasztalatainkat \u00f6sszegezt\u00fck. <jats:italic>Beteganyag \u00e9s\n                        m\u00f3dszerek:<\/jats:italic> 2012. m\u00e1rcius 1. \u00e9s 2021. november 31. k\u00f6z\u00f6tt 14 feln\u0151tt\n                    beteg\u00fcnkn\u00e9l v\u00e9gezt\u00fcnk mastoidobliter\u00e1ci\u00f3s m\u0171t\u00e9tet csontporral (7 beteg), illetve\n                        BonAlive<jats:sup>\u00ae<\/jats:sup> granul\u00e1tummal (7 beteg). A mastoidobliter\u00e1ci\u00f3t\n                    megel\u0151z\u0151en a betegek mindk\u00e9t csoportban \u00e1tlagosan t\u00f6bb mint 3 f\u00fclm\u0171t\u00e9ten\n                    (nyitott vagy z\u00e1rt technik\u00e1j\u00fa tympanoplastica) estek \u00e1t. A m\u0171t\u00e9teket k\u00f6vet\u0151en\n                    mindk\u00e9t csoportban elemezt\u00fck a panaszok v\u00e1ltoz\u00e1s\u00e1t, az audiol\u00f3giai eredm\u00e9nyek\n                    alakul\u00e1s\u00e1t \u00e9s a betegek \u00e9letmin\u0151s\u00e9g\u00e9ben bek\u00f6vetkezett v\u00e1ltoz\u00e1sokat.\n                        <jats:italic>Eredm\u00e9nyek:<\/jats:italic> A mastoidobliter\u00e1ci\u00f3s m\u0171t\u00e9ti megold\u00e1s egyik\n                    betegcsoportban sem okozott cochlearis k\u00e1rosod\u00e1st. A csontporral t\u00f6rt\u00e9nt\n                    obliter\u00e1ci\u00f3t k\u00f6vet\u0151en gyakrabban tapasztaltunk elh\u00faz\u00f3d\u00f3 f\u00fclv\u00e1lad\u00e9koz\u00e1st \u00e9s\n                    esetenk\u00e9nt sz\u00e9d\u00fcl\u00e9st, mely panaszok id\u0151vel megsz\u0171ntek. A BonAlive<jats:sup>\u00ae<\/jats:sup>\n                    granul\u00e1tummal obliter\u00e1lt esetekben komplik\u00e1ci\u00f3t nem \u00e9szlelt\u00fcnk. Mindk\u00e9t\n                    betegcsoportban igen jelent\u0151s \u00e9letmin\u0151s\u00e9g-javul\u00e1st figyelt\u00fcnk meg.\n                        <jats:italic>K\u00f6vetkeztet\u00e9s:<\/jats:italic> A mastoidobliter\u00e1ci\u00f3s m\u0171t\u00e9tek \u2013 ak\u00e1r\n                    csontporral, ak\u00e1r BonAlive<jats:sup>\u00ae<\/jats:sup> granul\u00e1tummal v\u00e9gezve \u2013 gyakorlatunkban\n                    biztons\u00e1gos \u00e9s hat\u00e1sos megold\u00e1snak bizonyultak kor\u00e1bban otitis media suppurativa\n                    chronica cholesteatomatosa miatt ak\u00e1r nyitott, ak\u00e1r z\u00e1rt technik\u00e1val v\u00e9gzett,\n                    \u00e1lland\u00f3 b\u0171z\u00f6s f\u00fclv\u00e1lad\u00e9koz\u00e1ssal j\u00e1r\u00f3 esetekben. A BonAlive<jats:sup>\u00ae<\/jats:sup>\n                    granul\u00e1tummal v\u00e9gzett obliter\u00e1ci\u00f3k sz\u00e1mos el\u0151nnyel j\u00e1rnak a betegek sz\u00e1m\u00e1ra: az\n                    \u00fcveggranul\u00e1tum antibakteri\u00e1lis hat\u00e1s\u00fa, oszteokondukt\u00edv hat\u00e1s\u00fa (keretet biztos\u00edt\n                    a csont n\u00f6veked\u00e9s\u00e9hez), \u00e9s oszteoprodukt\u00edv hat\u00e1st is kiv\u00e1lt (stimul\u00e1lja a\n                    csontosod\u00e1st). Orv Hetil. 2022; 163(21): 838\u2013845.<\/jats:p>","DOI":"10.1556\/650.2022.32477","type":"journal-article","created":{"date-parts":[[2022,11,18]],"date-time":"2022-11-18T13:36:23Z","timestamp":1668778583000},"page":"838-845","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":2,"title":["Mastoidobliter\u00e1ci\u00f3hoz haszn\u00e1lt csontpor \u00e9s bioakt\u00edv \u00fcveggranul\u00e1tum a cholesteatoma seb\u00e9szet\u00e9ben"],"prefix":"10.1556","volume":"163","author":[{"given":"Imre","family":"Gerlinger","sequence":"first","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, F\u00fcl-Orr-G\u00e9g\u00e9szeti \u00e9s Fej-Nyakseb\u00e9szeti Klinika P\u00e9cs, Munk\u00e1csy M. u. 2., 7621 Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00c9va","family":"Szab\u00f3","sequence":"additional","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, F\u00fcl-Orr-G\u00e9g\u00e9szeti \u00e9s Fej-Nyakseb\u00e9szeti Klinika P\u00e9cs, Munk\u00e1csy M. u. 2., 7621 Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Istv\u00e1n","family":"Szanyi","sequence":"additional","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, F\u00fcl-Orr-G\u00e9g\u00e9szeti \u00e9s Fej-Nyakseb\u00e9szeti Klinika P\u00e9cs, Munk\u00e1csy M. u. 2., 7621 Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tam\u00e1s","family":"Rost\u00e1s","sequence":"additional","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Orvosi K\u00e9palkot\u00f3 Klinika P\u00e9cs Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Istv\u00e1n","family":"Pap","sequence":"additional","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, F\u00fcl-Orr-G\u00e9g\u00e9szeti \u00e9s Fej-Nyakseb\u00e9szeti Klinika P\u00e9cs, Munk\u00e1csy M. u. 2., 7621 Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P\u00e9ter","family":"R\u00e9v\u00e9sz","sequence":"additional","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, F\u00fcl-Orr-G\u00e9g\u00e9szeti \u00e9s Fej-Nyakseb\u00e9szeti Klinika P\u00e9cs, Munk\u00e1csy M. u. 2., 7621 Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eszter","family":"Kopj\u00e1r","sequence":"additional","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, F\u00fcl-Orr-G\u00e9g\u00e9szeti \u00e9s Fej-Nyakseb\u00e9szeti Klinika P\u00e9cs, Munk\u00e1csy M. u. 2., 7621 Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"ref0","doi-asserted-by":"publisher","first-page":"1129","DOI":"10.1016\/j.otc.2006.08.007","article-title":"Mastoid obliteration","volume":"39","author":"Mehta RP","year":"2006","unstructured":"1 Mehta RP, Harris JP. 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