{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,21]],"date-time":"2025-12-21T10:23:17Z","timestamp":1766312597339},"reference-count":17,"publisher":"Akademiai Kiado Zrt.","issue":"31","license":[{"start":{"date-parts":[[2022,7,31]],"date-time":"2022-07-31T00:00:00Z","timestamp":1659225600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2022,7,31]]},"abstract":"<jats:p>A paragangliom\u00e1k a szimpatikus vagy paraszimpatikus ganglionokb\u00f3l kiindul\u00f3,\n                    t\u00f6bbs\u00e9g\u00fckben j\u00f3indulat\u00fa daganatok, de rosszindulat\u00fa form\u00e1juk is ismert. A\n                    fej-nyak r\u00e9gi\u00f3ban, a glomus caroticumban, illetve a vegetat\u00edv idegrendszer\n                    d\u00facl\u00e1nc\u00e1nak megfelel\u0151en a has\u00fcregben, illetve a mell\u00fcregben is el\u0151fordulhatnak.\n                    A 39 \u00e9ves f\u00e9rfi beteg kivizsg\u00e1l\u00e1sa extr\u00e9m magas v\u00e9rnyom\u00e1s\u00e9rt\u00e9kek, \u00e9jszakai\n                    izzad\u00e1s \u00e9s 10 kg-os fogy\u00e1s miatt kezd\u0151d\u00f6tt. A mellkas-CT-vizsg\u00e1lat a jobb oldali\n                    t\u00fcd\u0151kapuban \u00f3ri\u00e1si t\u00e9rfoglal\u00e1st \u00edrt le, a bronchoszk\u00f3pos mintav\u00e9tel sikertelen\n                    volt. Jobb oldali thoracotomi\u00e1b\u00f3l mintav\u00e9tel t\u00f6rt\u00e9nt, reszekci\u00f3ra a kifejezett\n                    adh\u00e9zi\u00f3k, illetve a sz\u00edv\u00e9rintetts\u00e9g miatt nem volt lehet\u0151s\u00e9g. A sz\u00f6vettani\n                    vizsg\u00e1lat eredm\u00e9nye paraganglioma lett, ezt a laborvizsg\u00e1latok is t\u00e1mogatt\u00e1k.\n                    Ennek megfelel\u0151n szomatosztatinanal\u00f3g-ter\u00e1pi\u00e1t kezdt\u00fcnk, majd\n                    <jats:sup>131<\/jats:sup>I-MIBG-kezel\u00e9st alkalmaztunk, j\u00f3 klinikai eredm\u00e9nnyel. A\n                    koronarogr\u00e1fia sor\u00e1n \u00e9szlelt\u00fck, hogy a jobb coronaria k\u00e9t margin\u00e1lis \u00e1ggal\n                    hozz\u00e1j\u00e1rul a mellkasi terime v\u00e9rell\u00e1t\u00e1s\u00e1hoz. Megfelel\u0151 el\u0151k\u00e9sz\u00edt\u00e9st k\u00f6vet\u0151en,\n                    sz\u00edv- \u00e9s mellkasseb\u00e9szeti beavatkoz\u00e1ssal a tumor elt\u00e1vol\u00edthat\u00f3nak bizonyult,\n                    ennek eredm\u00e9nyek\u00e9nt a posztoperat\u00edv szakban a beteg v\u00e9rnyom\u00e1scs\u00f6kkent\u0151it\n                    elhagytuk. A kontrollok sor\u00e1n tumormaradv\u00e1nyra utal\u00f3 jel nem volt. A\n                    v\u00e9rnyom\u00e1skiugr\u00e1sok ok\u00e1nak keres\u00e9sekor mer\u00fclj\u00f6n fel benn\u00fcnk a paraganglioma\n                    lehet\u0151s\u00e9ge is. Ezen esetekben az invaz\u00edv beavatkoz\u00e1sok, amennyiben nem el\u0151zi meg\n                    \u0151ket gy\u00f3gyszeres el\u0151k\u00e9sz\u00edt\u00e9s, ak\u00e1r fat\u00e1lis kimenetellel j\u00e1rhatnak. Az egyre\n                    sz\u00e9lesed\u0151 ter\u00e1pi\u00e1s lehet\u0151s\u00e9gek kihaszn\u00e1l\u00e1s\u00e1val \u00e9s az int\u00e9zetek k\u00f6z\u00f6tti\n                    kooper\u00e1ci\u00f3val az \u00f3ri\u00e1s-paragangliom\u00e1ban szenved\u0151 betegek is tumormentess\u00e9\n                    tehet\u0151k. Orv Hetil. 2022; 163(31): 1243\u20131249.<\/jats:p>","DOI":"10.1556\/650.2022.32529","type":"journal-article","created":{"date-parts":[[2022,11,19]],"date-time":"2022-11-19T00:31:04Z","timestamp":1668817864000},"page":"1243-1249","update-policy":"http:\/\/dx.doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":1,"title":["\u00d3ri\u00e1s mellkasi paraganglioma diagnosztikai neh\u00e9zs\u00e9gei \u00e9s ter\u00e1pi\u00e1s lehet\u0151s\u00e9gei"],"prefix":"10.1556","volume":"163","author":[{"given":"Erna","family":"Guly\u00e1s","sequence":"first","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Klinikai K\u00f6zpont, I. Belgy\u00f3gy\u00e1szati Klinika, Endokrinol\u00f3giai \u00e9s Anyagcsere Tansz\u00e9k P\u00e9cs, Ifj\u00fas\u00e1g u. 13., 7624 Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L\u00e1szl\u00f3","family":"Bajnok","sequence":"additional","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Klinikai K\u00f6zpont, I. Belgy\u00f3gy\u00e1szati Klinika, Endokrinol\u00f3giai \u00e9s Anyagcsere Tansz\u00e9k P\u00e9cs, Ifj\u00fas\u00e1g u. 13., 7624 Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Orsolya","family":"Nemes","sequence":"additional","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Klinikai K\u00f6zpont, I. 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