{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,11]],"date-time":"2026-02-11T18:00:37Z","timestamp":1770832837173,"version":"3.50.1"},"reference-count":49,"publisher":"Akademiai Kiado Zrt.","issue":"33","license":[{"start":{"date-parts":[[2022,8,14]],"date-time":"2022-08-14T00:00:00Z","timestamp":1660435200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2022,8,14]]},"abstract":"<jats:p>Bizonyos nyomelemek ionos, illetve komplexen k\u00f6t\u00f6tt vegy\u00fcletei n\u00e9lk\u00fcl\u00f6zhetetlenek\n                    sz\u00e1mtalan biok\u00e9miai folyamatban, a hum\u00e1n szervezet megfelel\u0151 m\u0171k\u00f6d\u00e9s\u00e9hez.\n                    Hi\u00e1nyuk vagy akkumul\u00e1ci\u00f3juk sz\u00e1mos eg\u00e9szs\u00e9g\u00fcgyi probl\u00e9m\u00e1t, betegs\u00e9get okoz.\n                    Kor\u00e1bban az inzulinrezisztencia \u00e9s a cukorbetegs\u00e9g kezel\u00e9s\u00e9ben a nyomelemeket\n                    kulcsfontoss\u00e1g\u00fa faktornak gondolt\u00e1k, azonban a diabetes kialakul\u00e1s\u00e1ban a\n                    nyomelemek hi\u00e1nya, fontoss\u00e1ga vagy a sz\u00f6v\u0151dm\u00e9nyek kialakul\u00e1s\u00e1ban \u00e9s kezel\u00e9s\u00e9ben\n                    a nyomelemstatus meg\u00edt\u00e9l\u00e9se, a p\u00f3tl\u00e1s fontoss\u00e1ga m\u00e9g ma is ellentmond\u00e1sos. A\n                    szerz\u0151k ez\u00e9rt \u00e1ttekintik a nyomelemek szerep\u00e9t a diabetes kialakul\u00e1s\u00e1ban,\n                    patogenezis\u00e9ben \u00e9s progresszi\u00f3j\u00e1ban. R\u00f6viden besz\u00e1molnak a cink(II), a\n                    mang\u00e1n(II, III), a r\u00e9z(I, II), a kr\u00f3m(III), a vas(II, III), a kobalt(II), a\n                    van\u00e1dium(III, IV, V), a molibd\u00e9n(IV, VI), a j\u00f3d(I), a szel\u00e9n(II, IV, VI) \u00e9s a\n                    l\u00edtium(I) hum\u00e1n szervezetben ismert legfontosabb folyamatair\u00f3l \u00e9s a diabetesszel\n                    \u00f6sszef\u00fcgg\u0151 biok\u00e9miai v\u00e1ltoz\u00e1sokr\u00f3l. R\u00e9szletezik a nyomelemstatus elt\u00e9r\u00e9seit\n                    diabetesben, kapcsolatukat a szabad gy\u00f6k\u00f6kkel \u00e9s az antioxid\u00e1ns v\u00e9delmi\n                    rendszerrel. R\u00e1t\u00e9rnek n\u00e9h\u00e1ny rizik\u00f3faktor t\u00e1rgyal\u00e1s\u00e1ra, amely s\u00falyosabb\n                    mikroelemhi\u00e1nyhoz \u00e9s sz\u00f6v\u0151dm\u00e9nyek kialakul\u00e1s\u00e1hoz vezet. Orv Hetil. 2022;\n                    163(33): 1303\u20131310.<\/jats:p>","DOI":"10.1556\/650.2022.32550","type":"journal-article","created":{"date-parts":[[2022,11,19]],"date-time":"2022-11-19T01:10:54Z","timestamp":1668820254000},"page":"1303-1310","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":4,"title":["Diabetes \u00e9s a nyomelemek"],"prefix":"10.1556","volume":"163","author":[{"given":"Kl\u00e1ra","family":"Szentmih\u00e1lyi","sequence":"first","affiliation":[{"name":"Term\u00e9szettudom\u00e1nyi Kutat\u00f3k\u00f6zpont, Anyag- \u00e9s K\u00f6rnyezetk\u00e9miai Int\u00e9zet Budapest, Magyar tud\u00f3sok k\u00f6r\u00fatja 2., 1117 Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Szilvia","family":"Kl\u00e9bert","sequence":"additional","affiliation":[{"name":"Term\u00e9szettudom\u00e1nyi Kutat\u00f3k\u00f6zpont, Anyag- \u00e9s K\u00f6rnyezetk\u00e9miai Int\u00e9zet Budapest, Magyar tud\u00f3sok k\u00f6r\u00fatja 2., 1117 Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anik\u00f3","family":"Somogyi","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Belgy\u00f3gy\u00e1szati \u00e9s Hematol\u00f3giai Klinika Budapest Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"ref0","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1007\/s00404-009-0955-x","article-title":"Status of essential trace metals in biological samples of diabetic mother and their neonates","volume":"280","author":"1 Afridi","year":"2009","unstructured":"1 Afridi HI, Kazi TG, Kazi N, et al. 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