{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T23:06:18Z","timestamp":1785366378480,"version":"3.55.0"},"reference-count":16,"publisher":"Akademiai Kiado Zrt.","issue":"27","license":[{"start":{"date-parts":[[2022,7,3]],"date-time":"2022-07-03T00:00:00Z","timestamp":1656806400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2022,7,3]]},"abstract":"<jats:p>A Kikuchi\u2013Fujimoto-betegs\u00e9g (histiocyt\u00e1s nekrotiz\u00e1l\u00f3 lymphadenitis) egy\n                    autolimit\u00e1lt folyamat, melynek kiv\u00e1lt\u00f3 t\u00e9nyez\u0151ihez soroljuk az\n                    Epstein\u2013Barr-v\u00edrust, a hum\u00e1n herpeszv\u00edrust, a HIV-et, a B19 parvov\u00edrust, a\n                    paromyxovirusokat, a SARS-CoV-2-t, illetve a <jats:italic>Toxoplasm\u00e1t<\/jats:italic> \u00e9s a\n                        <jats:italic>Yersini\u00e1t<\/jats:italic>. A pontos diagn\u00f3zis fel\u00e1ll\u00edt\u00e1s\u00e1hoz\n                    elengedhetetlen a nyirokcsom\u00f3-biopszia, melyet sz\u00f6vettani vizsg\u00e1lat k\u00f6vet. Egy\n                    45 \u00e9ves n\u0151beteg igazolt SARS-CoV-2-fert\u0151z\u00e9st k\u00f6vet\u0151en egyoldali nyaki\n                    nyirokcsom\u00f3-megnagyobbod\u00e1ssal, l\u00e1zzal, rekedts\u00e9ggel, illetve nyel\u00e9si\n                    nehez\u00edtetts\u00e9ggel \u00e9rkezett ambulanci\u00e1nkra. SARS-CoV-2-fert\u0151z\u00e9se a t\u00fcnetek\n                    megjelen\u00e9se el\u0151tt 1 h\u00f3nappal kett\u0151s pozit\u00edv (orrgarati) gyorsteszt form\u00e1j\u00e1ban\n                    ker\u00fclt bizony\u00edt\u00e1sra, melyet 2 hetes otthoni karant\u00e9n k\u00f6vetett. Felszabad\u00edt\u00f3\n                    teszt nem k\u00e9sz\u00fclt, az ambulanter vizsg\u00e1lat el\u0151tt v\u00e9gzett COVID\u201319 orrgarati\n                    gyorsteszt negat\u00edv eredm\u00e9nyt produk\u00e1lt. A fizik\u00e1lis status felm\u00e9r\u00e9s\u00e9t oszt\u00e1lyos\n                    felv\u00e9tel k\u00f6vette, melynek sor\u00e1n intrav\u00e9n\u00e1s antibiotikumter\u00e1pia indult\n                    (Augmentin, 3 \u00d7 1,2 g; Klion, 2 \u00d7 100 mg) szteroidter\u00e1pi\u00e1val p\u00e1rhuzamosan\n                    (Solu-Medrol, 2 \u00d7 125 mg). A nyaki-mellkasi CT jobb oldali retropharyngealis\n                    t\u00e1lyogot \u00edrt le, nyaki nyirokcsom\u00f3-megnagyobbod\u00e1ssal p\u00e1rhuzamosan. S\u00fcrg\u0151s\n                    tracheotomi\u00e1t, illetve nyaki felt\u00e1r\u00e1st v\u00e9gezt\u00fcnk nyirokcsom\u00f3-biopszi\u00e1val\n                    egybek\u00f6tve. A felt\u00e1r\u00e1s sor\u00e1n t\u00e1lyogra utal\u00f3 jelet nem tal\u00e1ltunk. A sz\u00f6vettani\n                    vizsg\u00e1lat nekrotiz\u00e1l\u00f3 lymphadenitist igazolt. Annak ellen\u00e9re, hogy a betegs\u00e9g\n                    autolimit\u00e1lt, l\u00e1that\u00f3, hogy a fenti esetben a SARS-CoV-2-fert\u0151z\u00e9st k\u00f6vet\u0151en\n                    kialakul\u00f3 nyaki lymphadenopathia \u00e9letet vesz\u00e9lyeztet\u0151 \u00e1llapot okozott, mely\n                    miatt l\u00e9gcs\u0151metsz\u00e9s, nyaki felt\u00e1r\u00e1s, illetve nyirokcsom\u00f3-biopszia volt sz\u00fcks\u00e9ges\n                    a beteg \u00e1llapot\u00e1nak javul\u00e1s\u00e1\u00e9rt \u00e9s betegs\u00e9g\u00e9nek pontos tiszt\u00e1z\u00e1s\u00e1\u00e9rt. A\n                    kialakult sz\u00f6veti exsudatum nyaki t\u00e1lyog k\u00e9p\u00e9t ut\u00e1nozta a CT-felv\u00e9teleken. Az\n                    \u00e1ltalunk felkeresett, nagysz\u00e1m\u00fa szakirodalmi k\u00f6zlem\u00e9nyben hasonl\u00f3 beavatkoz\u00e1s\n                    nem ker\u00fclt le\u00edr\u00e1sra. A nyaki felt\u00e1r\u00e1s, a tracheotomia, illetve a nyaki\n                    nyirokcsom\u00f3knak mint ,,trigger\u201d z\u00f3n\u00e1knak az elt\u00e1vol\u00edt\u00e1sa jelen eset\u00fcnkben a\n                    teljes gy\u00f3gyul\u00e1st eredm\u00e9nyezte. Fontos a SARS-CoV-2, illetve a\n                    Kikuchi\u2013Fujimoto-betegs\u00e9g korrel\u00e1ci\u00f3j\u00e1nak tov\u00e1bbi meger\u0151s\u00edt\u00e9se, pontosabb\n                    tiszt\u00e1z\u00e1sa. Orv Hetil. 2022; 163(27): 1061\u20131065.<\/jats:p>","DOI":"10.1556\/650.2022.32559","type":"journal-article","created":{"date-parts":[[2022,7,4]],"date-time":"2022-07-04T11:37:48Z","timestamp":1656934668000},"page":"1061-1065","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.1","source":"Crossref","is-referenced-by-count":4,"title":["SARS-CoV-2-fert\u0151z\u00e9s okozta Kikuchi\u2013Fujimoto-betegs\u00e9g sikeres gy\u00f3gy\u00edt\u00e1sa"],"prefix":"10.1556","volume":"163","author":[{"given":"Zolt\u00e1n","family":"Iszlai","sequence":"first","affiliation":[{"name":"Borsod-Aba\u00faj-Zempl\u00e9n Megyei K\u00f6zponti K\u00f3rh\u00e1z \u00e9s Egyetemi Oktat\u00f3k\u00f3rh\u00e1z, F\u00fcl-Orr-G\u00e9g\u00e9szeti \u00e9s Fej-Nyakseb\u00e9szeti Oszt\u00e1ly Miskolc, Szentp\u00e9teri kapu 72\u201376., 3526 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00e1szl\u00f3","family":"T\u00f6r\u00f6k","sequence":"additional","affiliation":[{"name":"Borsod-Aba\u00faj-Zempl\u00e9n Megyei K\u00f6zponti K\u00f3rh\u00e1z \u00e9s Egyetemi Oktat\u00f3k\u00f3rh\u00e1z, F\u00fcl-Orr-G\u00e9g\u00e9szeti \u00e9s Fej-Nyakseb\u00e9szeti Oszt\u00e1ly Miskolc, Szentp\u00e9teri kapu 72\u201376., 3526 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika","family":"T\u00f3th","sequence":"additional","affiliation":[{"name":"Orsz\u00e1gos Onkol\u00f3giai Int\u00e9zet, Daganatpatol\u00f3giai K\u00f6zpont, Seb\u00e9szeti \u00e9s Molekul\u00e1ris Patol\u00f3giai Oszt\u00e1ly Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tam\u00e1s","family":"Karosi","sequence":"additional","affiliation":[{"name":"Borsod-Aba\u00faj-Zempl\u00e9n Megyei K\u00f6zponti K\u00f3rh\u00e1z \u00e9s Egyetemi Oktat\u00f3k\u00f3rh\u00e1z, F\u00fcl-Orr-G\u00e9g\u00e9szeti \u00e9s Fej-Nyakseb\u00e9szeti Oszt\u00e1ly Miskolc, Szentp\u00e9teri kapu 72\u201376., 3526 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"1 Park SG, Koo HR, Jang K, et al. 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