{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T05:03:35Z","timestamp":1697691815315},"reference-count":41,"publisher":"Akademiai Kiado Zrt.","issue":"1","content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2023,1,8]]},"abstract":"<jats:p><jats:italic>Bevezet\u00e9s:<\/jats:italic> Annak ellen\u00e9re, hogy Rom\u00e1ni\u00e1ban a hum\u00e1n\n                    immundeficientia-v\u00edrus (HIV) okozta megbeteged\u00e9sek sz\u00e1ma cs\u00f6kken\u0151 tendenci\u00e1t\n                    mutat, a HIV-fert\u0151z\u00e9s tov\u00e1bbra is a tuberkul\u00f3zis (TBC) egyik legfontosabb\n                    kock\u00e1zati t\u00e9nyez\u0151je. <jats:italic>C\u00e9lkit\u0171z\u00e9s:<\/jats:italic> A TBC\u2013HIV-t\u00e1rsfert\u0151z\u00e9s\n                    saj\u00e1toss\u00e1gainak elemz\u00e9se a rom\u00e1niai Maros megy\u00e9ben 2014 \u00e9s 2020 k\u00f6z\u00f6tt.\n                        <jats:italic>M\u00f3dszer:<\/jats:italic> A vizsg\u00e1lati csoport adatainak retrospekt\u00edv m\u00f3don\n                    t\u00f6rt\u00e9n\u0151 feldolgoz\u00e1sa \u00e9s \u00f6sszehasonl\u00edt\u00e1sa nemzetk\u00f6zileg k\u00f6z\u00f6lt adatokkal (hasonl\u00f3\n                    betegcsoport, ugyanebben a f\u00f6ldrajzi r\u00e9gi\u00f3ban, 2004 \u00e9s 2013 k\u00f6z\u00f6tt).\n                        <jats:italic>Eredm\u00e9nyek:<\/jats:italic> A vizsg\u00e1latba 40, TBC\u2013HIV-t\u00e1rsfert\u0151z\u00e9ssel\n                    k\u00f3rism\u00e9zett beteget vontunk be: 24 f\u00e9rfi, 16 n\u0151, 22 vid\u00e9ki k\u00f6rnyezetb\u0151l\n                    sz\u00e1rmaz\u00f3, 22 doh\u00e1nyz\u00f3, 20 alkohol-, illetve 4 k\u00e1b\u00edt\u00f3szer-fogyaszt\u00f3 volt.\n                    T\u00f6bbs\u00e9g\u00fckre rossz \u00e9letk\u00f6r\u00fclm\u00e9nyek \u00e9s az otthoni k\u00f6rnyezet t\u00falzs\u00fafolts\u00e1ga volt\n                    jellemz\u0151. 30 p\u00e1ciens a 26\u201340 \u00e9ves korcsoporthoz tartozott, ami jelent\u0151sen\n                    befoly\u00e1solta szem\u00e9lyes \u00e9s t\u00e1rsadalmi fejl\u0151d\u00e9s\u00fcket. 25 beteg szerzett\n                    immunhi\u00e1nyos t\u00fcnetcsoporttal (AIDS) ker\u00fclt k\u00f3rism\u00e9z\u00e9sre. 28 t\u00fcd\u0151-TBC-t, 1\n                    extrapulmonalis \u00e9s 11 vegyes form\u00e1t azonos\u00edtottunk. 13 esetben nem siker\u00fclt\n                    k\u00f3rokoz\u00f3t kimutatni; a k\u00f3rism\u00e9z\u00e9shez val\u00f3sz\u00edn\u0171s\u00e9gi krit\u00e9riumokra t\u00e1maszkodtunk\n                    (epidemiol\u00f3gia, klinikai \u00e9s k\u00e9palkot\u00e1si m\u00f3dszerek). Szignifik\u00e1nsan cs\u00f6kkent a\n                    hepatitis, a parazitog\u00e9n, illetve m\u00e1s, opportunista fert\u0151z\u00e9sek sz\u00e1ma, viszont\n                    megn\u00f6vekedett az anaemia, az idegrendszeri \u00e9s a l\u00e9gz\u0151rendszeri megbeteged\u00e9sek\n                    gyakoris\u00e1ga. Szint\u00e9n szignifik\u00e1nsan cs\u00f6kkent a gy\u00f3gyszerrezisztens form\u00e1k\n                    el\u0151fordul\u00e1sa \u00e9s a hal\u00e1loz\u00e1si ar\u00e1ny is. <jats:italic>Megbesz\u00e9l\u00e9s:<\/jats:italic> A\n                    TBC\u2013HIV-t\u00e1rsfert\u0151z\u00e9ses betegek t\u00f6bbs\u00e9g\u00e9nek rosszak az \u00e9letk\u00f6r\u00fclm\u00e9nyei, emiatt a\n                    vizsg\u00e1latok \u00e9s a kezel\u00e9s ter\u00e9n nem mutatnak megfelel\u0151 egy\u00fcttm\u0171k\u00f6d\u00e9st. A HIV\/AIDS\n                    k\u00eds\u00e9rte TBC nagyobb val\u00f3sz\u00edn\u0171s\u00e9ggel okoz sz\u00f6v\u0151dm\u00e9nyeket, gy\u00f3gyszer-rezisztenci\u00e1t\n                    \u00e9s magas hal\u00e1loz\u00e1si ar\u00e1nyt. A betegs\u00e9gek k\u00f3rism\u00e9z\u00e9se \u00e9rdek\u00e9ben minden TBC-s\n                    betegn\u00e9l fontos sz\u0171rni a HIV-fert\u0151z\u00e9st, illetve a HIV-fert\u0151z\u00f6ttekn\u00e9l a TBC-t.\n                        <jats:italic>K\u00f6vetkeztet\u00e9s:<\/jats:italic> Mindk\u00e9t betegs\u00e9g megel\u0151z\u00e9se, korai\n                    k\u00f3rism\u00e9z\u00e9se \u00e9s kezel\u00e9se nagyobb figyelmet ig\u00e9nyel, ak\u00e1rcsak a szeg\u00e9nys\u00e9g\n                    felsz\u00e1mol\u00e1sa \u00e9s a magasabb szint\u0171 oktat\u00e1s el\u0151seg\u00edt\u00e9se. Orv Hetil. 2023; 164(1):\n                    19\u201328.<\/jats:p>","DOI":"10.1556\/650.2023.32631","type":"journal-article","created":{"date-parts":[[2023,1,9]],"date-time":"2023-01-09T14:00:13Z","timestamp":1673272813000},"page":"19-28","update-policy":"http:\/\/dx.doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":0,"title":["A tuberkul\u00f3zis \u00e9s a HIV-fert\u0151z\u00e9s kapcsolat\u00e1nak jellemz\u0151i Maros megy\u00e9ben, Rom\u00e1ni\u00e1ban"],"prefix":"10.1556","volume":"164","author":[{"given":"H\u00e9di-Katalin","family":"S\u00e1rk\u00f6zi","sequence":"first","affiliation":[{"name":"Marosv\u00e1s\u00e1rhelyi \u201eGeorge Emil Palade\u201d Orvosi, Gy\u00f3gyszer\u00e9szeti, Tudom\u00e1ny \u00e9s Technol\u00f3giai Egyetem, T\u00fcd\u0151gy\u00f3gy\u00e1szati Tansz\u00e9k K\u00e1rp\u00e1tok s\u00e9t\u00e1ny 43\/A, 3\/11. 540296, Marosv\u00e1s\u00e1rhely, Maros megye Rom\u00e1nia"},{"name":"Maros Megyei Klinikai K\u00f3rh\u00e1z, T\u00fcd\u0151gy\u00f3gy\u00e1szati Klinika Marosv\u00e1s\u00e1rhely Rom\u00e1nia"},{"name":"Marosv\u00e1s\u00e1rhelyi \u201eGeorge Emil Palade\u201d Orvosi, Gy\u00f3gyszer\u00e9szeti, Tudom\u00e1ny \u00e9s Technol\u00f3giai Egyetem, Doktori Iskola Marosv\u00e1s\u00e1rhely Rom\u00e1nia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edith-Simona","family":"Iano\u0219i","sequence":"additional","affiliation":[{"name":"Marosv\u00e1s\u00e1rhelyi \u201eGeorge Emil Palade\u201d Orvosi, Gy\u00f3gyszer\u00e9szeti, Tudom\u00e1ny \u00e9s Technol\u00f3giai Egyetem, T\u00fcd\u0151gy\u00f3gy\u00e1szati Tansz\u00e9k K\u00e1rp\u00e1tok s\u00e9t\u00e1ny 43\/A, 3\/11. 540296, Marosv\u00e1s\u00e1rhely, Maros megye Rom\u00e1nia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Delia-Liana","family":"Rachi\u0219","sequence":"additional","affiliation":[{"name":"Maros Megyei Klinikai K\u00f3rh\u00e1z, T\u00fcd\u0151gy\u00f3gy\u00e1szati Klinika Marosv\u00e1s\u00e1rhely Rom\u00e1nia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mioara","family":"Szathm\u00e1ry","sequence":"additional","affiliation":[{"name":"Marosv\u00e1s\u00e1rhelyi \u201eGeorge Emil Palade\u201d Orvosi, Gy\u00f3gyszer\u00e9szeti, Tudom\u00e1ny \u00e9s Technol\u00f3giai Egyetem, T\u00fcd\u0151gy\u00f3gy\u00e1szati Tansz\u00e9k K\u00e1rp\u00e1tok s\u00e9t\u00e1ny 43\/A, 3\/11. 540296, Marosv\u00e1s\u00e1rhely, Maros megye Rom\u00e1nia"},{"name":"Marosv\u00e1s\u00e1rhelyi \u201eGeorge Emil Palade\u201d Orvosi, Gy\u00f3gyszer\u00e9szeti, Tudom\u00e1ny \u00e9s Technol\u00f3giai Egyetem, Doktori Iskola Marosv\u00e1s\u00e1rhely Rom\u00e1nia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"G\u00eerbovan","sequence":"additional","affiliation":[{"name":"Marosv\u00e1s\u00e1rhelyi \u201eGeorge Emil Palade\u201d Orvosi, Gy\u00f3gyszer\u00e9szeti, Tudom\u00e1ny \u00e9s Technol\u00f3giai Egyetem, Fert\u0151z\u0151 Betegs\u00e9gek Tansz\u00e9k Marosv\u00e1s\u00e1rhely Rom\u00e1nia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cornelia-Bianca","family":"Tudor","sequence":"additional","affiliation":[{"name":"Marosv\u00e1s\u00e1rhelyi \u201eGeorge Emil Palade\u201d Orvosi, Gy\u00f3gyszer\u00e9szeti, Tudom\u00e1ny \u00e9s Technol\u00f3giai Egyetem, Mikrobiol\u00f3gia Tansz\u00e9k Marosv\u00e1s\u00e1rhely Rom\u00e1nia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriana","family":"Neago\u0219","sequence":"additional","affiliation":[{"name":"Marosv\u00e1s\u00e1rhelyi \u201eGeorge Emil Palade\u201d Orvosi, Gy\u00f3gyszer\u00e9szeti, Tudom\u00e1ny \u00e9s Technol\u00f3giai Egyetem, F\u00fcl-Orr-G\u00e9g\u00e9szeti Tansz\u00e9k Marosv\u00e1s\u00e1rhely Rom\u00e1nia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriela","family":"Jimborean","sequence":"additional","affiliation":[{"name":"Marosv\u00e1s\u00e1rhelyi \u201eGeorge Emil Palade\u201d Orvosi, Gy\u00f3gyszer\u00e9szeti, Tudom\u00e1ny \u00e9s Technol\u00f3giai Egyetem, T\u00fcd\u0151gy\u00f3gy\u00e1szati Tansz\u00e9k K\u00e1rp\u00e1tok s\u00e9t\u00e1ny 43\/A, 3\/11. 540296, Marosv\u00e1s\u00e1rhely, Maros megye Rom\u00e1nia"},{"name":"Maros Megyei Klinikai K\u00f3rh\u00e1z, T\u00fcd\u0151gy\u00f3gy\u00e1szati Klinika Marosv\u00e1s\u00e1rhely Rom\u00e1nia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"ref0","unstructured":"1. 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