{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T02:08:03Z","timestamp":1780970883924,"version":"3.54.1"},"reference-count":37,"publisher":"Akademiai Kiado Zrt.","issue":"15","license":[{"start":{"date-parts":[[2023,4,16]],"date-time":"2023-04-16T00:00:00Z","timestamp":1681603200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2023,4,16]]},"abstract":"<jats:p><jats:italic>Bevezet\u00e9s:<\/jats:italic> Fenyeget\u0151 korasz\u00fcl\u00e9s eset\u00e9n <jats:italic>in utero<\/jats:italic>\n                    transzport javasolt, ez azonban nem mindig lehets\u00e9ges. A postnatalis transzport\n                    alatti ell\u00e1t\u00e1s jelent\u0151sen befoly\u00e1solja a sz\u00e1ll\u00edtott betegek kimenetel\u00e9t.\n                        <jats:italic>C\u00e9lkit\u0171z\u00e9s:<\/jats:italic> Tanulm\u00e1nyunk c\u00e9lja volt a betegek jellemz\u0151inek,\n                    ell\u00e1t\u00e1suk \u00e9s a neonatalis kimenetel trendjeinek vizsg\u00e1lata a 2008 \u00e9s 2021 k\u00f6z\u00f6tt\n                    postnatalis sz\u00e1ll\u00edt\u00e1st ig\u00e9nyl\u0151 korasz\u00fcl\u00f6ttekben. <jats:italic>M\u00f3dszer:<\/jats:italic>\n                    Retrospekt\u00edv vizsg\u00e1latot v\u00e9gezt\u00fcnk az \u00edrott \u00e9s az elektronikus betegdokument\u00e1ci\u00f3\n                    \u00e1ttekint\u00e9s\u00e9vel. A vizsg\u00e1lt trendeket \u201ejoinpoint\u201d regresszi\u00f3s anal\u00edzissel\n                    \u00e9rt\u00e9kelt\u00fck, illetve \u00e9ves sz\u00e1zal\u00e9kos v\u00e1ltoz\u00e1ssal (APC) jellemezt\u00fck.\n                        <jats:italic>Eredm\u00e9nyek:<\/jats:italic> A vizsg\u00e1latba 177 korasz\u00fcl\u00f6ttet v\u00e1lasztottunk\n                    be. A sz\u00e1ll\u00edt\u00e1sok sz\u00e1ma nem szignifik\u00e1ns n\u00f6vekv\u0151 trendet mutatott (APC = 6,8%, p\n                    = 0,087). A 60 percn\u00e9l hosszabb helysz\u00edni ell\u00e1t\u00e1sok ar\u00e1nya szignifik\u00e1nsan\n                    emelkedett (APC = 7,4%, p = 0,016). 2008 \u00e9s 2010 k\u00f6z\u00f6tt a g\u00e9pi l\u00e9legeztet\u00e9s\n                    alkalmaz\u00e1sa a sz\u00e1ll\u00edt\u00e1sok sor\u00e1n emelkedett (APC = 36,4%, p = 0,578), majd a\n                    vizsg\u00e1lati id\u0151szak h\u00e1tral\u00e9v\u0151 r\u00e9sz\u00e9ben cs\u00f6kken\u0151 tendenci\u00e1t mutatott (APC = \u20137,2%,\n                    p = 0,068). A 40% feletti oxig\u00e9nkoncentr\u00e1ci\u00f3 haszn\u00e1lata szignifik\u00e1nsan cs\u00f6kkent\n                    (APC = \u20139,5%, p = 0,043). A 150 mg\/kg-n\u00e1l kisebb surfactantd\u00f3zisok ar\u00e1nya\n                    szint\u00e9n cs\u00f6kken\u0151 tendenci\u00e1t mutatott (APC = \u20137,65%, p = 0,162), m\u00edg a 180 mg\/kg\n                    felettiek sz\u00e1ma szignifik\u00e1nsan emelkedett (APC = 8,5%, p = 0,031). Az\n                    \u00fajsz\u00fcl\u00f6ttek hossz\u00fa t\u00e1v\u00fa kimeneti mutat\u00f3i egyar\u00e1nt javul\u00f3 tendenci\u00e1t mutattak.\n                        <jats:italic>Megbesz\u00e9l\u00e9s:<\/jats:italic> Vizsg\u00e1latunk sor\u00e1n az ell\u00e1t\u00e1s noninvazivit\u00e1s\n                    fel\u00e9 mutat\u00f3 trendjei mellett a sz\u00e1ll\u00edtott korasz\u00fcl\u00f6ttek javul\u00f3 kimenetel\u00e9t\n                    \u00e9szlelt\u00fck. <jats:italic>K\u00f6vetkeztet\u00e9s:<\/jats:italic> Vizsg\u00e1latunk felgyors\u00edthatja a\n                    sz\u00e1ll\u00edt\u00e1s alatti ell\u00e1t\u00e1s folyamatban l\u00e9v\u0151 szeml\u00e9letv\u00e1lt\u00e1s\u00e1t, el\u0151seg\u00edtheti a\n                    vonatkoz\u00f3 protokollok, illetve elj\u00e1r\u00e1srendek fejleszt\u00e9s\u00e9t, melyek egy\u00fcttesen\n                    jav\u00edthatj\u00e1k a tercier centrumon k\u00edv\u00fcl sz\u00fcletett korasz\u00fcl\u00f6ttek \u00e9letkil\u00e1t\u00e1sait.\n                    Orv Hetil. 2023; 164(15): 571\u2013576.<\/jats:p>","DOI":"10.1556\/650.2023.32735","type":"journal-article","created":{"date-parts":[[2023,4,21]],"date-time":"2023-04-21T05:27:50Z","timestamp":1682054870000},"page":"571-576","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":3,"title":["A respir\u00e1ci\u00f3s distressz szindr\u00f3ma kezel\u00e9s\u00e9nek trendjei a Debreceni Egyetem Klinikai K\u00f6zpontj\u00e1ba sz\u00e1ll\u00edtott igen \u00e9retlen korasz\u00fcl\u00f6ttekben"],"prefix":"10.1556","volume":"164","author":[{"given":"Andr\u00e1s","family":"Balajthy","sequence":"first","affiliation":[{"name":"Debreceni Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Klinikai K\u00f6zpont, Gyermekgy\u00f3gy\u00e1szati Klinika, Neonatol\u00f3giai Tansz\u00e9k Debrecen, Nagyerdei krt. 98., 4032 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Panna Eszter","family":"Kov\u00e1cs","sequence":"additional","affiliation":[{"name":"Debreceni Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar Debrecen Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariann","family":"M\u00e1rki","sequence":"additional","affiliation":[{"name":"Debreceni Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Klinikai K\u00f6zpont, Gyermekgy\u00f3gy\u00e1szati Klinika, Neonatol\u00f3giai Tansz\u00e9k Debrecen, Nagyerdei krt. 98., 4032 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magdolna","family":"Riszter","sequence":"additional","affiliation":[{"name":"Debreceni Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Klinikai K\u00f6zpont, Gyermekgy\u00f3gy\u00e1szati Klinika, Neonatol\u00f3giai Tansz\u00e9k Debrecen, Nagyerdei krt. 98., 4032 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Nagy","sequence":"additional","affiliation":[{"name":"Debreceni Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Klinikai K\u00f6zpont, Gyermekgy\u00f3gy\u00e1szati Klinika, Perinat\u00e1lis Intenz\u00edv Centrum Debrecen Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gergely","family":"Bal\u00e1zs","sequence":"additional","affiliation":[{"name":"Debreceni Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Klinikai K\u00f6zpont, Gyermekgy\u00f3gy\u00e1szati Klinika, Neonatol\u00f3giai Tansz\u00e9k Debrecen, Nagyerdei krt. 98., 4032 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"ref0","doi-asserted-by":"publisher","first-page":"1039","DOI":"10.1001\/jama.2015.10244","article-title":"Trends in care practices, morbidity, and mortality of extremely preterm neonates, 1993-2012","volume":"314","author":"1 Stoll","year":"2015","unstructured":"1 Stoll BJ, Hansen NI, Bell EF, et al. Trends in care practices, morbidity, and mortality of extremely preterm neonates, 1993-2012. JAMA 2015; 314: 1039-1051.","journal-title":"JAMA"},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"2 Mihalicza P, Cs\u00e1k\u00e1ny G, Szab\u00f3 M. Mortality rates of very low birth weight and very low gestational age newborns in Hungary. The EuroHOPE study. [Igen kis s\u00faly\u00fa vagy 32. geszt\u00e1ci\u00f3s h\u00e9tn\u00e9l \u00e9retlenebb korasz\u00fcl\u00f6ttek hal\u00e1loz\u00e1si mutat\u00f3i Magyarorsz\u00e1gon a EuroHOPE kutat\u00e1s t\u00fckr\u00e9ben.] Orv Hetil. 2016; 157: 1649-1656. [Hungarian]","DOI":"10.1556\/650.2016.30586"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"3 Balla G, Szab\u00f3 M. Chronic morbidities of premature newborns. [Korasz\u00fcl\u00f6ttek kr\u00f3nikus ut\u00f3betegs\u00e9gei.] Orv Hetil. 2013; 154: 1498-1511. 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Pediatrics 2010; 126: 443-456.","journal-title":"Pediatrics"},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"6 Manuck TA, Levy PT, Gyamfi-Bannerman C, et al. Prenatal and perinatal determinants of lung health and disease in early life. A National Heart, Lung, and Blood Institute Workshop report. JAMA Pediatr. 2016; 170: e154577.","DOI":"10.1001\/jamapediatrics.2015.4577"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1203\/00006450-199709000-00016","article-title":"Manual ventilation with a few large breaths at birth compromises the therapeutic effect of subsequent surfactant replacement in immature lambs","volume":"42","author":"7 Bj\u00f6rklund","year":"1997","unstructured":"7 Bj\u00f6rklund LJ, Ingimarsson J, Curstedt T, et al. Manual ventilation with a few large breaths at birth compromises the therapeutic effect of subsequent surfactant replacement in immature lambs. Pediatr Res. 1997; 42: 348-355.","journal-title":"Pediatr Res"},{"key":"ref7","doi-asserted-by":"publisher","unstructured":"8 Klingenberg C, Wheeler KI, McCallion N, et al. Volume-targeted versus pressure-limited ventilation in neonates. Cochrane Database Syst Rev. 2017; 10: CD003666.","DOI":"10.1002\/14651858.CD003666.pub4"},{"key":"ref8","doi-asserted-by":"publisher","unstructured":"9 Schm\u00f6lzer GM, Kumar M, Pichler G, et al. Non-invasive versus invasive respiratory support in preterm infants at birth: systematic review and meta-analysis. BMJ 2013; 347: f5980. Erratum: BMJ. 2014; 348: g58.","DOI":"10.1136\/bmj.f5980"},{"key":"ref9","doi-asserted-by":"publisher","unstructured":"10 Subramaniam P, Ho JJ, Davis PG. Prophylactic nasal continuous positive airway pressure for preventing morbidity and mortality in very preterm infants. Cochrane Database Syst Rev. 2016; 6: CD001243. 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Arch Dis Child Fetal Neonatal Ed. 2014; 99: F181-F188.","DOI":"10.1136\/archdischild-2013-305555"},{"key":"ref14","doi-asserted-by":"publisher","first-page":"358","DOI":"10.1001\/jamapediatrics.2019.6055","article-title":"Neonatal mortality after interhospital transfer of pregnant women for imminent very preterm birth in Illinois","volume":"174","author":"15 Shah","year":"2020","unstructured":"15 Shah KP, deRegnier RO, Grobman WA, et al. Neonatal mortality after interhospital transfer of pregnant women for imminent very preterm birth in Illinois. JAMA Pediatr. 2020; 174: 358-365.","journal-title":"JAMA Pediatr"},{"key":"ref15","doi-asserted-by":"publisher","unstructured":"16 Mohamed MA, Aly H. Transport of premature infants is associated with increased risk for intraventricular haemorrhage. 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Simulated transport alters surfactant homeostasis and causes dose-dependent changes in respiratory function in neonatal Sprague-Dawley rats. J Perinat Med. 2010; 38: 535-543.","DOI":"10.1515\/jpm.2010.080"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1542\/peds.84.1.43","article-title":"Adverse events during interhospital transport: physiologic deterioration associated with pretransport severity of illness","volume":"84","author":"Kanter RK","year":"1989","unstructured":"20 Kanter RK, Tompkins JM. Adverse events during interhospital transport: physiologic deterioration associated with pretransport severity of illness. 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J Paediatr Child Health 1999; 35: 530-535.","journal-title":"J Paediatr Child Health"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"170","DOI":"10.1016\/j.amj.2010.04.001","article-title":"Safety of surfactant administration before transport of premature infants","volume":"29","author":"Biniwale M","year":"2010","unstructured":"32 Biniwale M, Kleinman M. Safety of surfactant administration before transport of premature infants. Air Med J. 2010; 29: 170-177.","journal-title":"Air Med J"},{"key":"ref32","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1159\/000349928","article-title":"European consensus guidelines on the management of neonatal respiratory distress syndrome in preterm infants - 2013 update","volume":"103","author":"33 Sweet","year":"2013","unstructured":"33 Sweet DG, Carnielli V, Greisen G, et al. European consensus guidelines on the management of neonatal respiratory distress syndrome in preterm infants - 2013 update. Neonatology 2013; 103: 353-368.","journal-title":"Neonatology"},{"key":"ref33","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1055\/s-2004-823779","article-title":"A randomized, multicenter masked comparison trial of poractant alfa (Curosurf) versus beractant (Survanta) in the treatment of respiratory distress syndrome in preterm infants","volume":"21","author":"34 Ramanathan","year":"2004","unstructured":"34 Ramanathan R, Rasmussen MR, Gerstmann DR, et al. A randomized, multicenter masked comparison trial of poractant alfa (Curosurf) versus beractant (Survanta) in the treatment of respiratory distress syndrome in preterm infants. 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