{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T07:35:50Z","timestamp":1769931350703,"version":"3.49.0"},"reference-count":34,"publisher":"Akademiai Kiado Zrt.","issue":"17","content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2023,4,30]]},"abstract":"<jats:p><jats:italic>Bevezet\u00e9s:<\/jats:italic> A COVID\u201319-pand\u00e9mia sor\u00e1n az intenz\u00edv oszt\u00e1lyon\n                    kezelt betegek hal\u00e1loz\u00e1sa, b\u00e1r orsz\u00e1gonk\u00e9nt elt\u00e9r\u0151, de minden\u00fctt dr\u00e1maian nagy\n                    volt (20\u201360%). A rizik\u00f3faktorok azonos\u00edt\u00e1sa seg\u00edts\u00e9get ny\u00fajt a betegs\u00e9g\n                    patomechanizmus\u00e1nak meg\u00e9rt\u00e9s\u00e9ben, \u00e9s t\u00e1mpontot ad a vesz\u00e9lyeztetett betegek\n                    kisz\u0171r\u00e9s\u00e9hez, a progn\u00f3zis becsl\u00e9s\u00e9hez \u00e9s esetleg a megfelel\u0151 kezel\u00e9si modalit\u00e1s\n                    alkalmaz\u00e1s\u00e1hoz is. <jats:italic>C\u00e9lkit\u0171z\u00e9s:<\/jats:italic> Intenz\u00edv oszt\u00e1lyunkra felvett\n                    betegeken v\u00e9gzett vizsg\u00e1latunk a demogr\u00e1fiai \u00e9s \u00e1llapots\u00falyoss\u00e1gi faktorok\n                    elemz\u00e9se mellett a kezel\u00e9si modalit\u00e1s v\u00e1ltoz\u00e1s\u00e1nak hat\u00e1s\u00e1t is vizsg\u00e1lta a s\u00falyos\n                    \u00e1llapot\u00fa fert\u0151z\u00f6tt betegek kimenetel\u00e9re a COVID\u201319-j\u00e1rv\u00e1ny 3. \u00e9s 4. hull\u00e1m\u00e1ban.\n                        <jats:italic>M\u00f3dszer:<\/jats:italic> Retrospekt\u00edv, megfigyel\u00e9ses vizsg\u00e1latban\n                    r\u00f6gz\u00edtett\u00fck a s\u00falyos l\u00e9gz\u00e9si el\u00e9gtelens\u00e9ggel, koronav\u00edrus-fert\u0151z\u00e9s miatt felvett\n                    betegeink demogr\u00e1fiai, klinikai, kezel\u00e9si \u00e9s kimeneteli adatait.\n                        <jats:italic>Eredm\u00e9nyek:<\/jats:italic> \u00d6sszesen 88 beteg adatait dolgoztuk fel. A\n                    betegek 53%-a volt f\u00e9rfi, az \u00e9letkor medi\u00e1n \u00e9rt\u00e9ke 65 \u00e9v, a medi\u00e1n BMI 29\n                        kg\/m<jats:sup>2<\/jats:sup> volt. Nem invaz\u00edv l\u00e9legeztet\u00e9st 81%-ban, endotrachealis\n                    intub\u00e1l\u00e1st 45%-ban, hasra ford\u00edt\u00e1st 59%-ban alkalmaztunk. Vazopresszor-kezel\u00e9sre\n                    44%-ban volt sz\u00fcks\u00e9g, szekunder infekci\u00f3 36%-ban l\u00e9pett fel. A t\u00fal\u00e9l\u00e9s 41%-os\n                    volt. A t\u00fal\u00e9l\u00e9si rizik\u00f3faktorokat t\u00f6bbv\u00e1ltoz\u00f3s modellez\u00e9ssel is vizsg\u00e1ltuk. Az\n                    alacsonyabb \u00e9letkor \u00e9s APACHE II. pontsz\u00e1m mellett a nem diabeteses \u00e1llapot j\u00e1rt\n                    jobb t\u00fal\u00e9l\u00e9si es\u00e9llyel. A j\u00e1rv\u00e1ny sor\u00e1n a betegek kezel\u00e9se folyamatosan\n                    v\u00e1ltozott \u2013 ennek hat\u00e1sait is k\u00f6vett\u00fck. Igazol\u00f3dott, hogy a kezel\u00e9si protokoll\n                    v\u00e1ltoz\u00e1sa kedvez\u0151 hat\u00e1ssal volt a t\u00fal\u00e9l\u00e9sre (OR = 0,18 [95% CI: 0,04\u20130,76], p =\n                    0,01976) m\u00e9g az APACHE II. pontsz\u00e1mra, nemre, BMI-re, k\u00e9t t\u00e1rsbetegs\u00e9gre \u00e9s k\u00e9t\n                    gy\u00f3gyszerre (remdesivir, tocilizumab) kontroll\u00e1lva is.\n                        <jats:italic>K\u00f6vetkeztet\u00e9s:<\/jats:italic> A t\u00fal\u00e9l\u00e9s tekintet\u00e9ben az alacsonyabb\n                    \u00e9letkor \u00e9s APACHE II. pontsz\u00e1m, illetve a diabetes hi\u00e1nya volt kedvez\u0151 t\u00e9nyez\u0151.\n                    A kezdeti alacsony t\u00fal\u00e9l\u00e9si r\u00e1ta (15%) a kezel\u00e9si protokoll v\u00e1ltoz\u00e1sa mellett\n                    szignifik\u00e1nsan emelkedett (49%). K\u00f6zlem\u00e9ny\u00fcnk c\u00e9lja, hogy biztassunk minden\n                    magyar int\u00e9zm\u00e9nyt saj\u00e1t adatainak k\u00f6zl\u00e9s\u00e9re, \u00e9s ennek jegy\u00e9ben kezdem\u00e9nyezz\u00fck\n                    egy hazai, szakmai adatb\u00e1zis kialak\u00edt\u00e1s\u00e1t. Orv Hetil. 2023; 164(17):\n                    651\u2013658.<\/jats:p>","DOI":"10.1556\/650.2023.32762","type":"journal-article","created":{"date-parts":[[2023,4,30]],"date-time":"2023-04-30T12:59:40Z","timestamp":1682859580000},"page":"651-658","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":2,"title":["A k\u00f3rh\u00e1zi t\u00fal\u00e9l\u00e9st meghat\u00e1roz\u00f3 t\u00e9nyez\u0151k a COVID\u201319-j\u00e1rv\u00e1ny 3. \u00e9s 4. hull\u00e1ma idej\u00e9n s\u00falyos koronav\u00edrus-fert\u0151z\u00e9ssel intenz\u00edv oszt\u00e1lyra felvett betegekben"],"prefix":"10.1556","volume":"164","author":[{"given":"\u00c1bel","family":"Koller","sequence":"first","affiliation":[{"name":"Dr. Manninger Jen\u0151 Baleseti K\u00f6zpont Budapest, Fiumei \u00fat 17., 1081 Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eszter","family":"M\u00e1rkus","sequence":"additional","affiliation":[{"name":"Dr. Manninger Jen\u0151 Baleseti K\u00f6zpont Budapest, Fiumei \u00fat 17., 1081 Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tam\u00e1s","family":"Ferenci","sequence":"additional","affiliation":[{"name":"\u00d3budai Egyetem, \u00c9lettani Szab\u00e1lyoz\u00e1sok Kutat\u00f3k\u00f6zpont Budapest Magyarorsz\u00e1g"},{"name":"Budapesti Corvinus Egyetem, Statisztika Tansz\u00e9k Budapest Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00e1bor","family":"Nardai","sequence":"additional","affiliation":[{"name":"Dr. Manninger Jen\u0151 Baleseti K\u00f6zpont Budapest, Fiumei \u00fat 17., 1081 Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"ref0","unstructured":"References"},{"key":"ref1","unstructured":"[1] Cassiano, N, Beatriz, A, Vitorino, F, Maia, SI, Iii, DO, Lourdes, M De, et al. (2020) Perinatal outcomes in pregnant women with hypertensive syndromes\u202f: An integra-tive review Introduction According to the guidelines of the American College of Obstetricians and Gynecologists presence of proteinuria and signs of severity. Based on this ,1-19."},{"key":"ref2","unstructured":"[2] Kon\u00e9, J, Traor\u00e9, SO, Tour\u00e9, MK, Doumbia, D, Camara, D, Kon\u00e9, P, et al. (2018) Impact de la Pr\u00e9-\u00c9clampsie sur la Morbidit\u00e9 et la Mortalit\u00e9 N\u00e9onatales Neonatal outcome in preeclampsia,19 (December):66-70."},{"key":"ref3","unstructured":"[3] David, M, Moura, R De, Margotto, PR, Costa, KN, Rita, M, Garbi, C. (2021) Hyper-tension induced by pregnancy and neonatal outcome\u202f: Results from a retrospective cohort study in preterm under,1-12."},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"[4] Faso, B. (2015) L ' \u00e9clampsie au CHU-Yalgado de Ouagadougou ( Burkina Faso ) du 1 er avril 2013 au 31 mars 2014, 316-23.","DOI":"10.1007\/s13149-015-0456-z"},{"key":"ref5","unstructured":"[5] Roudet, V. (2014) Pr\u00e9valence de l ' acidose respiratoire chez les nouveau-n\u00e9s pr\u00e9sentant un pH art\u00e9riel inf\u00e9rieur \u00e0 7 , 20 \u00e0 la naissance par l ' utilisation de la m\u00e9thode d ' Eisenberg et comparaison de leur pronostic To cite this version\u202f: HAL Id\u202f: dumas-01025887."},{"key":"ref6","doi-asserted-by":"publisher","unstructured":"[6] Thakur, J, Bhatta, NK, Singh, RR, Poudel, P, Lamsal, M. (2018) Prevalence of elec-trolyte disturbances in perinatal asphyxia\u202f: a prospective study, 1-6.","DOI":"10.1186\/s13052-018-0496-7"},{"key":"ref7","unstructured":"[7] Hamdi, LELM, Aboussad, A. (2013) Nouveau-n\u00e9 de m\u00e8re pr\u00e9\u00e9clamptique\u202f: morbidit\u00e9 et mortalit\u00e9 au CHU Mohammed VI en 2010."},{"key":"ref8","unstructured":"[8] License, I. (2017) Pr\u00e9-\u00e9clampsie s\u00e9v\u00e8re avant 34 SA\u202f: diagnostic , prise en charge et pronostic materno-foetal. \u00c9tat des lieux au CHRU de Brest de janvier 2011 \u00e0 d\u00e9cembre 2014 C\u00e9line Guillemot To cite this version\u202f: HAL Id\u202f: dumas-01560524 UFR de M\u00e9decine et des Sciences d.;"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"3114","DOI":"10.7759\/cureus.31143","article-title":"Preeclampsia Incidence and Its Maternal and Neonatal Outcomes With Associated Risk Factors","author":"Khan","year":"2022","unstructured":"[9] Khan, B, Allah Yar,R, Khakwani A, et al. (2022) Preeclampsia Incidence and Its Maternal and Neonatal Outcomes With Associated Risk Factors. Cureus 14 (11): e31143.","journal-title":"Cureus 14 (11)"},{"key":"ref10","doi-asserted-by":"publisher","unstructured":"[10] Bromfield, SG, Ma Q, Devries, A, Inglis, T, Gordon, AS. (2023)The association be-tween hypertensive disorders during pregnancy and maternal and neonatal out-comes\u202f: a retrospective claims analysis. BMC Pregnancy Childbirth, 1-10.","DOI":"10.1186\/s12884-023-05818-9"},{"key":"ref11","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/j.annfar.2010.03.013","article-title":"Pronostic des nouveau-ne de m\u00e8res pr\u00e9\u00e9clamptiques","author":"Zupan-Simunek","year":"2010","unstructured":"[11] Zupan-Simunek, V, (2010) Pronostic des nouveau-ne de m\u00e8res pr\u00e9\u00e9clamptiques. Ann Fr Anesth Reanim, 2010;29 (5):e135-9.","journal-title":"Ann Fr Anesth Reanim 2010 29 (5)"},{"key":"ref12","doi-asserted-by":"publisher","unstructured":"[12] Thornton, C, Dahlen, H, Korda, A, Hennessy, A. (2013)The incidence of preec-lampsia and eclampsia and associated maternal mortality in Australia from popula-tion-linked. YMOB, 208 (6):476.e1-476.e5.","DOI":"10.1016\/j.ajog.2013.02.042"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/j.preghy.2020.01.006","article-title":"Maternal hypertension , preeclamp-sia , and risk of neonatal respiratory disorders in a large-prospective cohort study","author":"Tian","year":"2020","unstructured":"[13] Tian, T, Wang, L, Ye R, Liu, J, Ren, A. (2020) Maternal hypertension , preeclamp-sia , and risk of neonatal respiratory disorders in a large-prospective cohort study. Pregnancy Hypertens,131-7.","journal-title":"Pregnancy Hypertens"},{"key":"ref14","doi-asserted-by":"publisher","unstructured":"[14] Chahid, N, Boudana, S, Kabiri, M, Mrabet, M, Barkat, A. (2014) Retentissement f\u0153tal et n\u00e9onatal de l ' hypertension art\u00e9rielle gravidique\u202f: donn\u00e9es marocaines Fetal and neonatal impact of pregnancy-induced hypertension\u202f: J Pediatr Pueric.","DOI":"10.1016\/j.jpp.2014.04.005"},{"key":"ref15","unstructured":"[15] Belay, L, Id T, Yigezu, E, Urgie, T, Feyissa, GT. (2020) Maternal and perinatal out-come of preeclampsia without severe feature among pregnant women managed at a tertiary referral hospital in urban Ethiopia, 0001:1-10."},{"key":"ref16","doi-asserted-by":"publisher","unstructured":"[16] Uwizeyimana, P, Musabyemariya, E, Tengera, O, Collins, A. (2020) Neonatal Out-comes from Mothers with Hypertension Disorders of Pregnancy\u202f: A Retrospective Study at a Referral Hospital in,3 (2):193-203.","DOI":"10.4314\/rjmhs.v3i2.9"},{"key":"ref17","unstructured":"[17] Imane, MN. (2020) Les nouveau-n\u00e9s de m\u00e8res pr\u00e9-\u00e9clamptiques These, Maroc"},{"key":"ref18","unstructured":"[18] Danielle Christiane Kedy Koum et al. The Pan African Medical Journal - ISSN 1937-8688. Morbidit\u00e9 et facteurs de risque de mortalit\u00e9 n\u00e9onatale dans un h\u00f4pital de r\u00e9f\u00e9rence de Douala. Case report. 2015;8688."},{"key":"ref19","doi-asserted-by":"publisher","unstructured":"[19] Misganaw, FM, Marta, BB, Getie, LA. (2019) Perinatal outcomes of severe preec-lampsia \/ eclampsia and associated factors among mothers admitted in Amhara Re-gion. BMC Research Notes 12, Article number: 147","DOI":"10.1186\/s13104-019-4161-z"},{"key":"ref20","doi-asserted-by":"publisher","unstructured":"[20] Kelly, R, Ramaiah, SM, Sheridan, H, Cruickshank, H, Rudnicka, M, Kissack, C, et al. (2017) Dose-dependent relationship between acidosis at birth and likelihood of death or cerebral palsy,1-7.","DOI":"10.1136\/archdischild-2017-314034"},{"key":"ref21","doi-asserted-by":"publisher","unstructured":"[21] Indrio, F, Marchese, F, Rinaldi, M, Maffei, G, Dargenio, V, Cinquepalmi, R. (2022) Is acidemia at birth a risk factor for functional gastrointestinal disorders\u202f? Eur J Pe-diatr,3625-33.","DOI":"10.1007\/s00431-022-04565-x"},{"key":"ref22","doi-asserted-by":"publisher","unstructured":"[22] Cnattingius, S, Johansson, S, Razaz, N. (2020) Rates of metabolic acidosis at birth and Apgar score values at 1 , 5 , and 10 min in term infants\u202f: a Swedish cohort study, 48 (5):514-5.","DOI":"10.1515\/jpm-2019-0429"},{"key":"ref23","doi-asserted-by":"publisher","unstructured":"[23] Lyu, X, Weiyuan, S, Jingxiao, Z, Yuqian, Z. (2021) Morbidity and maternal and in-fant outcomes of hypertensive disorder in pregnancy in China in 2018,1194-204.","DOI":"10.1111\/jch.14248"},{"key":"ref24","doi-asserted-by":"publisher","unstructured":"[24] Boiro, D, Faye, PM, Gueye, M, Sow, A, Dieng, A, Ndongo, AA, et al. (2018) La pr\u00e9-\u00e9clampsie\u202f: quelles complications chez le nouveau-n\u00e9\u202f? J Pediatr Pueric.","DOI":"10.1016\/j.jpp.2018.09.009"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"1130","DOI":"10.1016\/S2214-109X(19)30220-7","article-title":"Major causes of death in preterm infants in selected hospitals in Ethiopia (SIP): a prospective, cross-sectional, observational study","author":"Muhe","year":"2019","unstructured":"[25] Muhe, LM, McClure, EM, Nigussie, AK, Mekasha, A, Worku, B, Worku, A, et al. (2019) Major causes of death in preterm infants in selected hospitals in Ethiopia (SIP): a prospective, cross-sectional, observational study. Lancet Glob Heal, 7 (8):e1130-8.","journal-title":"Lancet Glob Heal 7 (8)"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1371\/journal.pone.0176090","article-title":"Antenatal corticosteroids for neonates born before 25 Weeks-A systematic review and meta-analysis","author":"Deshmukh","year":"2017","unstructured":"[26] Deshmukh, M, Patole, S. (2017) Antenatal corticosteroids for neonates born before 25 Weeks-A systematic review and meta-analysis. PLoS One,12 (5):1-15.","journal-title":"PLoS One 12 (5)"},{"key":"ref27","doi-asserted-by":"publisher","unstructured":"[27] Nathan, HL, Seed, PT, Hezelgrave, NL, De Greeff, A, Lawley, E, Conti-Ramsden, F, et al. (2018) Maternal and perinatal adverse outcomes in women with pre-eclampsia cared for at facility-level in South Africa: A prospective cohort study. J Glob Health, 8 (2).","DOI":"10.7189\/jogh.08.020401"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1371\/journal.pone.0223478","article-title":"Maternal and perinatal outcomes among women with hypertensive disorders in pregnancy in Kumasi, Ghana","author":"Dassah","year":"2019","unstructured":"[28] Dassah, ET, Kusi-Mensah, E, Morhe, ESK, Odoi, AT. (2019) Maternal and perinatal outcomes among women with hypertensive disorders in pregnancy in Kumasi, Ghana. PLoS One,14 (10):1-13.","journal-title":"PLoS One 14 (10)"},{"key":"ref29","doi-asserted-by":"publisher","unstructured":"[29] Kiondo, P, Tumwesigye, NM, Wandabwa, J, Wamuyu-Maina, G, Bimenya, GS, Okong, P. (2014) Adverse neonatal outcomes in women with pre-eclampsia in Mu-lago Hospital, Kampala, Uganda: a cross-sectional study. Pan Afr Med J,17 (Supp 1):7.","DOI":"10.11604\/pamjs.supp.2014.17.1.3014"},{"key":"ref30","doi-asserted-by":"publisher","first-page":"2789","DOI":"10.1080\/14767058.2016.1263295","article-title":"Ear-ly-onset preeclampsia is associated with perinatal mortality and severe neonatal morbidity","author":"Esch","year":"2017","unstructured":"[30] van Esch, JJA, van Heijst, AF, de Haan, AFJ, van der Heijden, OWH. (2017) Ear-ly-onset preeclampsia is associated with perinatal mortality and severe neonatal morbidity. J Matern Neonatal Med, 30 (23):2789-94.","journal-title":"J Matern Neonatal Med 30 (23)"},{"key":"ref31","unstructured":"[31] Hossain, S, Roy S, Kirk, K, Warren, C. (2019) Hypertensive Disorders in Pregnan-cy\u202f: Assessing Postnatal Quality of Care and Outcomes for Women and Their In-fants in Bangladesh. The Population Council, Inc"},{"key":"ref32","doi-asserted-by":"publisher","unstructured":"[32] Shen, M, Smith, GN, Rodger, M, White, RR, Walker, C, Wen, SW. (2017) Compar-ison of risk factors and outcomes of gestational hypertension and pre-eclampsia,1-13.","DOI":"10.1371\/journal.pone.0175914"},{"key":"ref33","doi-asserted-by":"publisher","unstructured":"[33] Kumari, A, Chakrawarty, A, Singh, A, Singh, R. (2014) Maternofoetal Complica-tions and Their Association with Proteinuria in a Tertiary Care Hospital of a De-veloping Country.","DOI":"10.1155\/2014\/431837"}],"container-title":["Orvosi Hetilap"],"original-title":[],"link":[{"URL":"https:\/\/akjournals.com\/view\/journals\/650\/164\/17\/article-p651.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/akjournals.com\/downloadpdf\/journals\/650\/164\/17\/article-p651.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/akjournals.com\/downloadpdf\/journals\/650\/164\/17\/article-p651.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T06:42:03Z","timestamp":1697697723000},"score":1,"resource":{"primary":{"URL":"https:\/\/akjournals.com\/view\/journals\/650\/164\/17\/article-p651.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,30]]},"references-count":34,"journal-issue":{"issue":"17"},"URL":"https:\/\/doi.org\/10.1556\/650.2023.32762","relation":{},"ISSN":["0030-6002","1788-6120"],"issn-type":[{"value":"0030-6002","type":"print"},{"value":"1788-6120","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,30]]}}}