{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T10:35:03Z","timestamp":1760524503611},"reference-count":10,"publisher":"Akademiai Kiado Zrt.","issue":"22","license":[{"start":{"date-parts":[[2023,6,4]],"date-time":"2023-06-04T00:00:00Z","timestamp":1685836800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2023,6,4]]},"abstract":"<jats:p>A daganatos betegs\u00e9gek okozz\u00e1k a magyarorsz\u00e1gi hal\u00e1lesetek k\u00f6zel egynegyed\u00e9t. A\n                    tumorreszekci\u00f3s m\u0171t\u00e9tek hossz\u00fa t\u00e1v\u00fa sikeress\u00e9g\u00e9t, vagyis a ki\u00fajul\u00e1s- \u00e9s\n                    \u00e1tt\u00e9telmentess\u00e9get, valamint a t\u00fal\u00e9l\u00e9st az aneszt\u00e9ziai m\u00f3dszerek is\n                    befoly\u00e1solj\u00e1k. Ezt igazolt\u00e1k a sejtteny\u00e9szeteken \u00e9s az \u00e1llatmodelleken v\u00e9gzett\n                    k\u00eds\u00e9rletek. Kider\u00fclt, hogy a propofol \u00e9s a helyi \u00e9rz\u00e9stelen\u00edt\u0151szerek \u2013 az\n                    inhal\u00e1ci\u00f3s anesztetikumokhoz \u00e9s az opioidokhoz k\u00e9pest \u2013 cs\u00f6kkentik a\n                    daganatsejtek \u00e9letk\u00e9pess\u00e9g\u00e9t \u00e9s \u00e1tt\u00e9telk\u00e9pz\u0151 potenci\u00e1ljukat. A betegcsoportokon\n                    v\u00e9gzett vizsg\u00e1latok azonban csak a propofol el\u0151ny\u00e9t igazolt\u00e1k az inhal\u00e1ci\u00f3s\n                    anesztetikumokhoz k\u00e9pest. Sajnos az \u00e1ltal\u00e1nos aneszt\u00e9zi\u00e1hoz a helyi\n                    \u00e9rz\u00e9stelen\u00edt\u0151szerek epiduralis, kieg\u00e9sz\u00edt\u0151 jelleg\u0171 alkalmaz\u00e1sa nem cs\u00f6kkentette\n                    a betegek ki\u00fajul\u00e1smentess\u00e9gi \u00e9s t\u00fal\u00e9l\u00e9si idej\u00e9t. Tov\u00e1bbi klinikai vizsg\u00e1latok\n                    sz\u00fcks\u00e9gesek, hogy a j\u00f6v\u0151ben kider\u00fclj\u00f6n, az egyes r\u00e1kt\u00edpusokban milyen a m\u0171t\u00e9ti\n                    \u00e9rz\u00e9stelen\u00edt\u00e9s t\u00e9nyleges hat\u00e1sa. Orv Hetil. 2023; 164(22): 843\u2013846.<\/jats:p>","DOI":"10.1556\/650.2023.32805","type":"journal-article","created":{"date-parts":[[2023,6,5]],"date-time":"2023-06-05T05:54:15Z","timestamp":1685944455000},"page":"843-846","update-policy":"http:\/\/dx.doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":2,"title":["A m\u0171t\u00e9ti \u00e9rz\u00e9stelen\u00edt\u00e9s hat\u00e1sa a daganatki\u00fajul\u00e1sra."],"prefix":"10.1556","volume":"164","author":[{"given":"Lajos","family":"Bog\u00e1r","sequence":"first","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Aneszteziol\u00f3giai \u00e9s Intenz\u00edv Ter\u00e1pi\u00e1s Int\u00e9zet P\u00e9cs, Ifj\u00fas\u00e1g \u00fat 13., 7624 Magyarorsz\u00e1g"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"425","reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"Lang, X. J.; Chen, X. D.; Zhao, J. C. 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