{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T02:02:48Z","timestamp":1784944968166,"version":"3.55.0"},"reference-count":33,"publisher":"Akademiai Kiado Zrt.","issue":"28","license":[{"start":{"date-parts":[[2023,7,16]],"date-time":"2023-07-16T00:00:00Z","timestamp":1689465600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2023,7,16]]},"abstract":"<jats:p>Szaruh\u00e1rtya-\u00e1t\u00fcltet\u00e9s (keratoplasztika) akkor sz\u00fcks\u00e9ges, amikor k\u00fcl\u00f6nb\u00f6z\u0151\n                    k\u00f3r\u00e1llapotok k\u00f6vetkezt\u00e9ben konzervat\u00edv kezel\u00e9ssel nem gy\u00f3gy\u00edthat\u00f3, s\u00falyos\n                    l\u00e1t\u00e1scs\u00f6kken\u00e9ssel j\u00e1r\u00f3 szaruh\u00e1rtyahom\u00e1lyok alakulnak ki, vagy a cornea szab\u00e1lyos\n                    szerkezete, g\u00f6rb\u00fclete torzul, funkci\u00f3ja elv\u00e9sz. A hum\u00e1n transzplant\u00e1ci\u00f3k k\u00f6z\u00f6tt\n                    a keratoplasztika a legsikeresebb m\u0171t\u00e9ti elj\u00e1r\u00e1s. Az ut\u00f3bbi \u00e9vtizedekben a\n                    perfor\u00e1l\u00f3 keratoplasztik\u00e1k hely\u00e9t egyre ink\u00e1bb \u00e1tveszik a lamell\u00e1ris\n                    transzplant\u00e1ci\u00f3k, amikor csak a cornea k\u00f3ros r\u00e9teg\u00e9t \u00fcltetj\u00fck \u00e1t. Az el\u00fcls\u0151\n                    forma a m\u00e9ly el\u00fcls\u0151 lamell\u00e1ris keratoplasztika (\u201edeep anterior lamellar\n                    keratoplasty\u201d \u2013 DALK), mely els\u0151sorban keratoconusban aj\u00e1nlott. A h\u00e1ts\u00f3\n                    lamell\u00e1ris transzplant\u00e1ci\u00f3 f\u0151 form\u00e1ja a Descemet lev\u00e1laszt\u00e1sos automatiz\u00e1lt\n                    endothelialis keratoplasztika (\u201eDescemet\u2019s stripping automated endothelial\n                    keratoplasty\u201d \u2013 DSAEK) \u00e9s a Descemet-membr\u00e1n endothelialis keratoplasztika\n                    (\u201eDescemet\u2019s membrane endothelial keratoplasty\u201d \u2013 DMEK). Indik\u00e1ci\u00f3ja az\n                    endothelium pusztul\u00e1s\u00e1val j\u00e1r\u00f3 sz\u00fcrkeh\u00e1lyog-m\u0171t\u00e9t ut\u00e1n kialakul\u00f3 keratopathia\n                    bullosa \u00e9s a Fuchs endothelialis dystrophia. A lamell\u00e1ris keratoplasztik\u00e1knak\n                    t\u00f6bb el\u0151ny\u00fck van a perfor\u00e1l\u00f3 m\u0171t\u00e9tekkel szemben. Jobb a posztoperat\u00edv\n                    l\u00e1t\u00f3\u00e9less\u00e9g, gyorsabb a sebgy\u00f3gyul\u00e1s, a betegrehabilit\u00e1ci\u00f3, \u00e9s az esetleges\n                    immunol\u00f3giai kil\u00f6k\u0151d\u00e9s lefoly\u00e1sa is enyh\u00e9bb \u00e9s jobban kezelhet\u0151. Orv Hetil.\n                    2023; 164(28): 1087\u20131093.<\/jats:p>","DOI":"10.1556\/650.2023.32822","type":"journal-article","created":{"date-parts":[[2023,7,19]],"date-time":"2023-07-19T05:33:22Z","timestamp":1689744802000},"page":"1087-1093","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":4,"title":["Szaruh\u00e1rtya-\u00e1t\u00fcltet\u00e9s a 21. sz\u00e1zad elej\u00e9n"],"prefix":"10.1556","volume":"164","author":[{"given":"L\u00e1szl\u00f3","family":"M\u00f3dis","sequence":"first","affiliation":[{"name":"Debreceni Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Szem\u00e9szeti Tansz\u00e9k Debrecen, Nagyerdei krt. 98., 4032 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikl\u00f3s","family":"Luk\u00e1cs","sequence":"additional","affiliation":[{"name":"Debreceni Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Szem\u00e9szeti Tansz\u00e9k Debrecen, Nagyerdei krt. 98., 4032 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e1ra","family":"Makhoul","sequence":"additional","affiliation":[{"name":"Debreceni Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Szem\u00e9szeti Tansz\u00e9k Debrecen, Nagyerdei krt. 98., 4032 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"ref0","doi-asserted-by":"publisher","first-page":"7","DOI":"10.4103\/ijmr.IJMR_141_19","article-title":"Corneal transplantation in the modern era","volume":"150","author":"1 Singh","year":"2019","unstructured":"1 Singh R, Gupta N, Vanathi M, et al. 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[Hungarian]"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1001\/jamaophthalmol.2015.4776","article-title":"Global survey of corneal transplantation and eye banking","volume":"134","author":"7 Gain","year":"2016","unstructured":"7 Gain P, Jullienne R, He Z, et al. Global survey of corneal transplantation and eye banking. JAMA Ophthalmol. 2016; 134: 167-173.","journal-title":"JAMA Ophthalmol"},{"key":"ref7","unstructured":"8 European Cornea and Cell transplantation Registry. Summary final report of the ECCTR project. Available from: https:\/\/ec.europa.eu\/research\/participants\/documents\/downloadPublic?documentIds=080166e5c9dc9246&appId=PPGMS [accessed: February 22, 2023]."},{"key":"ref8","unstructured":"9 Fodor M, Rentka A, P\u00e1sztor D, et al. Keratoplasty in Hungary based on the National Keratoplasty Registry (1992-2021). [Szaruh\u00e1rtya-\u00e1t\u00fcltet\u00e9s Magyarorsz\u00e1gon - az Orsz\u00e1gos Keratoplastica Regiszter adatai (1992-2021).] Szem\u00e9szet 2022; Supplementum I. 159: 24-25. [Hungarian]"},{"key":"ref9","doi-asserted-by":"publisher","first-page":"1165","DOI":"10.1136\/bjo.2006.112656","article-title":"Age-related differences in the normal human cornea: a laser scanning in vivo confocal microscopy study","volume":"91","author":"10 Niederer","year":"2007","unstructured":"10 Niederer RL, Perumal D, Sherwin T, et al. Age-related differences in the normal human cornea: a laser scanning in vivo confocal microscopy study. Br J Ophthalmol. 2007; 91: 1165-1169.","journal-title":"Br J Ophthalmol"},{"key":"ref10","unstructured":"11 Basak SK. Low endothelial cell count and clear corneal grafts. Indian J Ophthalmol. 2004; 52: 151-153."},{"key":"ref11","unstructured":"12 M\u00f3dis L, Kettesy B, Szalai E, et al. Experiences with endothelial keratoplasty. [Endothelialis keratoplasztik\u00e1val szerzett tapasztalatok.] Szem\u00e9szet 2009; 146: 35-40. [Hungarian]"},{"key":"ref12","doi-asserted-by":"publisher","first-page":"1396","DOI":"10.1016\/S0161-6420(03)00463-9","article-title":"Long-term graft survival after penetrating keratoplasty","volume":"110","author":"Thompson RW Jr.","year":"2003","unstructured":"13 Thompson RW Jr., Price MO, Bowers PJ, et al. Long-term graft survival after penetrating keratoplasty. Ophthalmology 2003; 110: 1396-1402.","journal-title":"Ophthalmology"},{"key":"ref13","doi-asserted-by":"publisher","first-page":"1720","DOI":"10.1097\/TP.0b013e3181903b0a","article-title":"Risk factors for human corneal graft failure within the Australian corneal graft registry","volume":"86","author":"14 Williams","year":"2008","unstructured":"14 Williams KA, Lowe M, Bartlett C, et al. Risk factors for human corneal graft failure within the Australian corneal graft registry. 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Clin Ophthalmol. 2020; 14: 3591-3597.","journal-title":"Clin Ophthalmol"},{"key":"ref16","doi-asserted-by":"publisher","unstructured":"17 Wu S, Xu J. Incidence and risk factors for post-penetrating keratoplasty glaucoma: a systematic review and meta-analysis. PLoS ONE 2017; 12: e0176261.","DOI":"10.1371\/journal.pone.0176261"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1016\/j.survophthal.2007.04.008","article-title":"Corneal graft rejection","volume":"52","author":"18 Panda","year":"2007","unstructured":"18 Panda A, Vanathi M, Kumar A, et al. Corneal graft rejection. Surv Ophthalmol. 2007; 52: 375-396.","journal-title":"Surv Ophthalmol"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"2419","DOI":"10.1016\/j.ophtha.2013.08.026","article-title":"The effect of donor age on penetrating keratoplasty for endothelial disease: graft survival after 10 years in the Cornea Donor Study","volume":"120","author":"19 Mannis","year":"2013","unstructured":"19 Mannis MJ, Holland EJ, Gal RL, et al. The effect of donor age on penetrating keratoplasty for endothelial disease: graft survival after 10 years in the Cornea Donor Study. Ophthalmology 2013; 120: 2419-2427.","journal-title":"Ophthalmology"},{"key":"ref19","doi-asserted-by":"publisher","unstructured":"20 Lakatos \u00c9, T\u00f3th BK, Nagy ZZs, et al. The effect of intraocular pressure on refractive power of the cornea and the human eye, based on the Liou-Brennan model eye. [A szemnyom\u00e1s v\u00e1ltoz\u00e1s\u00e1nak hat\u00e1sa a szaruh\u00e1rtya \u00e9s a szem t\u00f6r\u0151erej\u00e9re a Liou-Brennan-modellszem alapj\u00e1n.] Orv Hetil. 2022; 163: 1872-1879. [Hungarian]","DOI":"10.1556\/650.2022.32627"},{"key":"ref20","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1016\/j.ajo.2020.11.006","article-title":"Comparative study of long-term graft survival between penetrating keratoplasty and deep anterior lamellar keratoplasty","volume":"224","author":"21 Arundhati","year":"2021","unstructured":"21 Arundhati A, Chew MC, Lim L, et al. Comparative study of long-term graft survival between penetrating keratoplasty and deep anterior lamellar keratoplasty. Am J Ophthalmol. 2021; 224: 207-216.","journal-title":"Am J Ophthalmol"},{"key":"ref21","doi-asserted-by":"publisher","unstructured":"22 Keane M, Coster D, Ziaei M, et al. Deep anterior lamellar keratoplasty versus penetrating keratoplasty for treating keratoconus. Cochrane Database Syst Rev. 2014; 7: CD009700.","DOI":"10.1002\/14651858.CD009700.pub2"},{"key":"ref22","doi-asserted-by":"publisher","first-page":"417","DOI":"10.6002\/ect.2019.0123","article-title":"Systematic review and meta-analysis of clinical outcomes of penetrating keratoplasty versus deep anterior lamellar keratoplasty for keratoconus","volume":"18","author":"23 Song","year":"2020","unstructured":"23 Song Y, Zhang J, Pan Z. Systematic review and meta-analysis of clinical outcomes of penetrating keratoplasty versus deep anterior lamellar keratoplasty for keratoconus. Exp Clin Transplant. 2020; 18: 417-428.","journal-title":"Exp Clin Transplant"},{"key":"ref23","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1016\/j.ajo.2004.09.045","article-title":"Corneal endothelium and postoperative outcomes 15 years after penetrating keratoplasty","volume":"139","author":"24 Patel","year":"2005","unstructured":"24 Patel SV, Hodge DO, Bourne WM. Corneal endothelium and postoperative outcomes 15 years after penetrating keratoplasty. Am J Ophthalmol. 2005; 139: 311-319.","journal-title":"Am J Ophthalmol"},{"key":"ref24","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1097\/ICO.0b013e31823d0412","article-title":"Long-term graft survival in deep anterior lamellar keratoplasty","volume":"31","author":"25 Sarnicola","year":"2012","unstructured":"25 Sarnicola V, Toro P, Sarnicola C, et al. Long-term graft survival in deep anterior lamellar keratoplasty. Cornea 2012; 31: 621-626.","journal-title":"Cornea"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"153","DOI":"10.1016\/j.ajo.2016.07.025","article-title":"Incidence and risk factors of elevated intraocular pressure following deep anterior lamellar keratoplasty","volume":"170","author":"26 Huang","year":"2016","unstructured":"26 Huang OS, Mehta JS, Htoon HM, et al. Incidence and risk factors of elevated intraocular pressure following deep anterior lamellar keratoplasty. Am J Ophthalmol. 2016; 170: 153-160.","journal-title":"Am J Ophthalmol"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"1508","DOI":"10.1016\/j.ophtha.2018.03.050","article-title":"Five-year graft survival of Descemet membrane endothelial keratoplasty (EK) versus Descemet stripping EK and the effect of donor sex matching","volume":"125","author":"27 Price","year":"2018","unstructured":"27 Price DA, Kelley M, Price FW Jr., et al. Five-year graft survival of Descemet membrane endothelial keratoplasty (EK) versus Descemet stripping EK and the effect of donor sex matching. Ophthalmology 2018; 125: 1508-1514.","journal-title":"Ophthalmology"},{"key":"ref27","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1016\/j.ajo.2019.06.012","article-title":"Descemet membrane endothelial keratoplasty versus Descemet stripping automated endothelial keratoplasty and penetrating keratoplasty","volume":"207","author":"28 Woo","year":"2019","unstructured":"28 Woo JH, Ang M, Htoon HM, et al. Descemet membrane endothelial keratoplasty versus Descemet stripping automated endothelial keratoplasty and penetrating keratoplasty. Am J Ophthalmol. 2019; 207: 288-303.","journal-title":"Am J Ophthalmol"},{"key":"ref28","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1136\/bjophthalmol-2015-306837","article-title":"Descemet membrane endothelial keratoplasty","volume":"100","author":"29 Ang","year":"2016","unstructured":"29 Ang M, Wilkins MR, Mehta JS, et al. Descemet membrane endothelial keratoplasty. Br J Ophthalmol. 2016; 100: 15-21.","journal-title":"Br J Ophthalmol"},{"key":"ref29","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.jcjo.2015.09.014","article-title":"Comparison of intraocular pressure post penetrating keratoplasty vs Descemet's stripping endothelial keratoplasty","volume":"51","author":"30 Sharma","year":"2016","unstructured":"30 Sharma RA, Bursztyn LL, Golesic E, et al. Comparison of intraocular pressure post penetrating keratoplasty vs Descemet's stripping endothelial keratoplasty. 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