{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T03:11:33Z","timestamp":1785208293288,"version":"3.55.0"},"reference-count":12,"publisher":"Akademiai Kiado Zrt.","issue":"39","content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2023,10,1]]},"abstract":"<jats:p>A pajzsmirigyb\u0151l kiindul\u00f3 primer laph\u00e1mcarcinoma az endokrin tumorokra vonatkoz\u00f3\n                    WHO-klasszifik\u00e1ci\u00f3 leg\u00fajabb, 2023-ban megjelent 5. kiad\u00e1sa alapj\u00e1n az\n                    anaplasticus pajzsmirigy-carcinom\u00e1k csoportj\u00e1ba tartozik. Igen ritka\n                    el\u0151fordul\u00e1s\u00fa betegs\u00e9g, kedvez\u0151tlen progn\u00f3zis \u00e9s r\u00f6vid t\u00fal\u00e9l\u00e9si id\u0151 jellemzi.\n                    Tanulm\u00e1nyunk c\u00e9lja felh\u00edvni a figyelmet ennek a ritka k\u00f3rk\u00e9pnek a m\u0171t\u00e9ti,\n                    valamint ter\u00e1pi\u00e1s neh\u00e9zs\u00e9geire. A 68 \u00e9ves n\u0151beteget neh\u00e9zl\u00e9gz\u00e9s \u00e9s gyorsan\n                    n\u00f6vekv\u0151, jobb oldali nyaki terime miatt utalt\u00e1k int\u00e9zet\u00fcnk Fej-Nyak Seb\u00e9szeti\n                    Ambulanci\u00e1j\u00e1ra. A fizik\u00e1lis vizsg\u00e1lat sor\u00e1n a nyak jobb oldal\u00e1n fix\u00e1lt k\u00e9pletet\n                    \u00e9s a jobb oldali g\u00e9gef\u00e9l paresis\u00e9t \u00e9szlelt\u00fck. Az aspir\u00e1ci\u00f3s citol\u00f3giai vizsg\u00e1lat\n                    laph\u00e1mcarcinom\u00e1t v\u00e9lem\u00e9nyezett a pajzsmirigyben, a k\u00e9palkot\u00f3 vizsg\u00e1latok\n                        (<jats:sup>18<\/jats:sup>FDG-PET\/CT) kiz\u00e1rt\u00e1k az egy\u00e9b fej-nyaki r\u00e9gi\u00f3b\u00f3l t\u00f6rt\u00e9n\u0151\n                    kiindul\u00e1s lehet\u0151s\u00e9g\u00e9t. M\u0171t\u00e9tet v\u00e9gezt\u00fcnk, melynek sor\u00e1n a teljes pajzsmirigy\n                    elt\u00e1vol\u00edt\u00e1s\u00e1t k\u00eds\u00e9relt\u00fck meg. A sz\u00f6vettani vizsg\u00e1lat meger\u0151s\u00edtette a kor\u00e1bbi\n                    citol\u00f3giai vizsg\u00e1lat sor\u00e1n k\u00f3rism\u00e9zett, pajzsmirigy kiindul\u00e1s\u00fa laph\u00e1mcarcinom\u00e1t.\n                    A megkezdett palliat\u00edv sug\u00e1rter\u00e1pia ellen\u00e9re a beteg elhunyt. A pajzsmirigy\n                    primer laph\u00e1mcarcinom\u00e1j\u00e1nak felismer\u00e9se \u00e9s kezel\u00e9se komoly kih\u00edv\u00e1st jelent a\n                    seb\u00e9sznek, valamint a kezel\u00e9st v\u00e9gz\u0151 team tagjainak. A t\u00fal\u00e9l\u00e9s tekintet\u00e9ben a\n                    limit\u00e1lt sug\u00e1r-, valamint kemoter\u00e1pi\u00e1s v\u00e1laszk\u00e9szs\u00e9g miatt kiemelt szereppel b\u00edr\n                    a komplett seb\u00e9szi elt\u00e1vol\u00edt\u00e1s, valamint az esetlegesen jelen l\u00e9v\u0151, ter\u00e1pi\u00e1san\n                    c\u00e9lozhat\u00f3 molekul\u00e1ris patol\u00f3giai elt\u00e9r\u00e9sek azonos\u00edt\u00e1sa. Orv Hetil. 2023;\n                    164(39): 1556\u20131559.<\/jats:p>","DOI":"10.1556\/650.2023.32858","type":"journal-article","created":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T09:06:40Z","timestamp":1696151200000},"page":"1556-1559","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":3,"title":["A pajzsmirigy primer laph\u00e1mcarcinom\u00e1ja."],"prefix":"10.1556","volume":"164","author":[{"given":"Bernadett","family":"L\u00e9vay","sequence":"first","affiliation":[{"name":"Orsz\u00e1gos Onkol\u00f3giai Int\u00e9zet, Fej-Nyaki Daganatok Multidiszciplin\u00e1ris K\u00f6zpont Budapest, R\u00e1th Gy. u. 7\u20139., 1124 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Kiss","sequence":"additional","affiliation":[{"name":"Orsz\u00e1gos Onkol\u00f3giai Int\u00e9zet, Fej-Nyaki Daganatok Multidiszciplin\u00e1ris K\u00f6zpont Budapest, R\u00e1th Gy. u. 7\u20139., 1124 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferenc","family":"Oberna","sequence":"additional","affiliation":[{"name":"Orsz\u00e1gos Onkol\u00f3giai Int\u00e9zet, Fej-Nyaki Daganatok Multidiszciplin\u00e1ris K\u00f6zpont Budapest, R\u00e1th Gy. u. 7\u20139., 1124 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e1s","family":"Slez\u00e1k","sequence":"additional","affiliation":[{"name":"Orsz\u00e1gos Onkol\u00f3giai Int\u00e9zet, Daganatpatol\u00f3giai K\u00f6zpont, Seb\u00e9szeti \u00e9s Molekul\u00e1ris Patol\u00f3giai Oszt\u00e1ly Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erika","family":"T\u00f3th","sequence":"additional","affiliation":[{"name":"Orsz\u00e1gos Onkol\u00f3giai Int\u00e9zet, Daganatpatol\u00f3giai K\u00f6zpont, Seb\u00e9szeti \u00e9s Molekul\u00e1ris Patol\u00f3giai Oszt\u00e1ly Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"ref0","doi-asserted-by":"publisher","first-page":"474","DOI":"10.21037\/gs.2020.02.18","article-title":"Primary squamous cell carcinoma (PSCC) of the thyroid: a case report and review of the literature","volume":"9","author":"Sun","year":"2020","unstructured":"1. 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