{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T01:39:53Z","timestamp":1784943593344,"version":"3.55.0"},"reference-count":63,"publisher":"Akademiai Kiado Zrt.","issue":"40","license":[{"start":{"date-parts":[[2023,10,8]],"date-time":"2023-10-08T00:00:00Z","timestamp":1696723200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2023,10,8]]},"abstract":"<jats:p>Az urothelsejtes carcinoma a h\u00fagyutak leggyakoribb rosszindulat\u00fa daganata, amely\n                    a vesemedenc\u00e9ben, a h\u00fagyvezet\u00e9kben, a h\u00fagyh\u00f3lyagban \u00e9s ritk\u00e1n a h\u00fagycs\u0151ben\n                    alakul ki. Sz\u00f6vetileg az urothelsejtes carcinom\u00e1t nem invaz\u00edv, illetve invaz\u00edv\n                    kateg\u00f3ri\u00e1ba soroljuk. Az el\u0151bbi papillaris n\u00f6veked\u00e9s\u0171, \u00e1ltal\u00e1ban j\u00f3l\n                    differenci\u00e1lt \u00e9s kedvez\u0151 kimenetel\u0171, m\u00edg az ut\u00f3bbi infiltrat\u00edvan sz\u0171ri be a\n                    kiindul\u00e1si szerveket, jellemz\u0151en rosszul differenci\u00e1lt, \u00e9s gyakran rossz\n                    progn\u00f3zissal t\u00e1rsul. Invaz\u00edv urothelsejtes carcinoma eset\u00e9n a k\u00f3rlefoly\u00e1st\n                    els\u0151dlegesen az inv\u00e1zi\u00f3 m\u00e9lys\u00e9ge hat\u00e1rozza meg, az \u00fajabb adatok szerint viszont\n                    az urothelsejtes carcinoma morfol\u00f3giai vari\u00e1nsai elt\u00e9r\u0151en reag\u00e1lnak az\n                    onkol\u00f3giai kezel\u00e9sekre, tov\u00e1bb\u00e1 ezek biol\u00f3giai viselked\u00e9se is k\u00fcl\u00f6nb\u00f6z\u0151. Ezek az\n                    alt\u00edpusok \u00e9s vari\u00e1nsok haz\u00e1nkban, illetve nemzetk\u00f6zileg is jelent\u0151sen\n                    aluldiagnosztiz\u00e1ltak, ugyanis a sz\u00f6vettani k\u00f3risme krit\u00e9riumai sok esetben nem\n                    egy\u00e9rtelm\u0171ek. A h\u00fagy\u00fati daganatok legfrissebb, 2022. \u00e9vi WHO-klasszifik\u00e1ci\u00f3ja\n                    jelent\u0151sen pontos\u00edtotta az egyes alt\u00edpusok \u00e9s vari\u00e1nsok defin\u00edci\u00f3it. Ebben a\n                    dolgozatban az aktu\u00e1lis klasszifik\u00e1ci\u00f3b\u00f3l kiindulva \u00e1ttekintj\u00fck ezen alt\u00edpusok,\n                    illetve vari\u00e1nsok morfol\u00f3giai, immunhisztok\u00e9miai, differenci\u00e1ldiagnosztikai,\n                    prognosztikai \u00e9s predikt\u00edv jellemz\u0151it azzal a c\u00e9llal, hogy ezek min\u00e9l ink\u00e1bb\n                    megjelenjenek a mindennapi diagnosztik\u00e1ban. A munka c\u00e9lja tov\u00e1bb\u00e1 az\n                    urothelsejtes carcinoma egyes alt\u00edpusainak \u00e9s vari\u00e1nsainak bemutat\u00e1sa a hazai\n                    patol\u00f3gus-, onkol\u00f3gus- \u00e9s urol\u00f3gusk\u00f6z\u00f6ss\u00e9gnek az\u00e9rt, hogy az eddigi magas szint\u0171\n                    uroonkol\u00f3giai ell\u00e1t\u00e1s m\u00e9g ink\u00e1bb szem\u00e9lyre szabott\u00e1 v\u00e1lhasson. Orv Hetil. 2023;\n                    164(40): 1567\u20131582.<\/jats:p>","DOI":"10.1556\/650.2023.32881","type":"journal-article","created":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T10:12:43Z","timestamp":1697710363000},"page":"1567-1582","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":3,"title":["Az invaz\u00edv urothelsejtes carcinoma morfol\u00f3giai vari\u00e1nsai."],"prefix":"10.1556","volume":"164","author":[{"given":"Bogl\u00e1rka","family":"P\u00f3sfai","sequence":"first","affiliation":[{"name":"Szegedi Tudom\u00e1nyegyetem, Szent-Gy\u00f6rgyi Albert Orvostudom\u00e1nyi Kar, Pathologiai Int\u00e9zet Szeged, \u00c1llom\u00e1s u. 1., 6725 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fanni","family":"S\u00e1nta","sequence":"additional","affiliation":[{"name":"Szegedi Tudom\u00e1nyegyetem, Szent-Gy\u00f6rgyi Albert Orvostudom\u00e1nyi Kar, Pathologiai Int\u00e9zet Szeged, \u00c1llom\u00e1s u. 1., 6725 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Schubert","sequence":"additional","affiliation":[{"name":"Szegedi Tudom\u00e1nyegyetem, Szent-Gy\u00f6rgyi Albert Orvostudom\u00e1nyi Kar, Pathologiai Int\u00e9zet Szeged, \u00c1llom\u00e1s u. 1., 6725 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D\u00e1vid","family":"Semj\u00e9n","sequence":"additional","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar \u00e9s Klinikai K\u00f6zpont, Pathologiai Int\u00e9zet P\u00e9cs Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Jenei","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Patol\u00f3giai \u00e9s K\u00eds\u00e9rleti R\u00e1kkutat\u00f3 Int\u00e9zet Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda","family":"Varga","sequence":"additional","affiliation":[{"name":"Szegedi Tudom\u00e1nyegyetem, Szent-Gy\u00f6rgyi Albert Orvostudom\u00e1nyi Kar, Onkoter\u00e1pi\u00e1s Klinika Szeged Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Levente","family":"Kuthi","sequence":"additional","affiliation":[{"name":"Szegedi Tudom\u00e1nyegyetem, Szent-Gy\u00f6rgyi Albert Orvostudom\u00e1nyi Kar, Pathologiai Int\u00e9zet Szeged, \u00c1llom\u00e1s u. 1., 6725 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"1 Kov\u00e1cs PT, Juh\u00e1sz D, M\u00f3dos O, et al. 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World Health Organization, Geneva, 1973."},{"key":"ref3","unstructured":"4 Netto GJ, Amin MB, Berney DM, et al. (eds.) The 2022 World Health Organization classification of tumors of the urinary system and male genital organs - Part B: Prostate and urinary tract tumors. International Agency for Research on Cancer, Lyon, 2022."},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"5 Downes MR. Invasive urothelial carcinoma. Subtypes and divergent differentiation. In: Barber N, Ali A. (eds.) Urologic cancers. Chapter 1. [Internet]. Exon Publications, Brisbane, 2022.","DOI":"10.36255\/exon-publications-urologic-cancers-urothelial-carcinoma"},{"key":"ref5","doi-asserted-by":"publisher","first-page":"724","DOI":"10.1002\/1097-0142(19810215)47:4<724::AID-CNCR2820470417>3.0.CO;2-2","article-title":"Neurosecretory granules in small cell invasive carcinoma of the urinary bladder","volume":"47","author":"6 Cramer","year":"1981","unstructured":"6 Cramer SF, Aikawa M, Cebelin M. Neurosecretory granules in small cell invasive carcinoma of the urinary bladder. Cancer 1981; 47: 724-730.","journal-title":"Cancer"},{"key":"ref6","doi-asserted-by":"publisher","first-page":"197","DOI":"10.3109\/01913128309140790","article-title":"Small cell neuroendocrine carcinoma of the urinary bladder: report of three cases with ultrastructural analysis","volume":"4","author":"7 Davis","year":"1983","unstructured":"7 Davis BH, Ludwig ME, Cole SR, et al. Small cell neuroendocrine carcinoma of the urinary bladder: report of three cases with ultrastructural analysis. Ultrastruct Pathol. 1983; 4: 197-204.","journal-title":"Ultrastruct Pathol"},{"key":"ref7","doi-asserted-by":"publisher","first-page":"1533","DOI":"10.1016\/S0002-9440(10)62369-3","article-title":"Molecular genetic evidence for a common clonal origin of urinary bladder small cell carcinoma and coexisting urothelial carcinoma","volume":"166","author":"8 Cheng","year":"2005","unstructured":"8 Cheng L, Jones TD, McCarthy RP, et al. Molecular genetic evidence for a common clonal origin of urinary bladder small cell carcinoma and coexisting urothelial carcinoma. 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Urothelial carcinoma with divergent histologic differentiation (mixed histologic features) predicts the presence of locally advanced bladder cancer when detected at transurethral resection. Urology 2007; 70: 69-74.","journal-title":"Urology"},{"key":"ref16","doi-asserted-by":"publisher","first-page":"59","DOI":"10.14218\/jctp.2022.00035","article-title":"The Paris System for Reporting Urinary Cytology: an updated review","volume":"3","author":"Chen F","year":"2023","unstructured":"17 Chen F, Lin X. The Paris System for Reporting Urinary Cytology: an updated review. J Clin Transl Pathol. 2023; 3: 59-74.","journal-title":"J Clin Transl Pathol"},{"key":"ref17","doi-asserted-by":"publisher","first-page":"641","DOI":"10.1016\/j.path.2022.07.003","article-title":"Urothelial carcinoma: divergent differentiation and morphologic subtypes","volume":"15","author":"18 Gandhi","year":"2022","unstructured":"18 Gandhi J, Chen JF, Al-Ahmadie H. Urothelial carcinoma: divergent differentiation and morphologic subtypes. Surg Pathol Clin. 2022; 15: 641-659.","journal-title":"Surg Pathol Clin"},{"key":"ref18","doi-asserted-by":"publisher","first-page":"1759","DOI":"10.1038\/bjc.2014.89","article-title":"Serum total hCG\u03b2 level is an independent prognostic factor in transitional cell carcinoma of the urothelial tract","volume":"110","author":"19 Douglas","year":"2014","unstructured":"19 Douglas J, Sharp A, Chau C, et al. Serum total hCG\u03b2 level is an independent prognostic factor in transitional cell carcinoma of the urothelial tract. Br J Cancer 2014; 110: 1759-1766.","journal-title":"Br J Cancer"},{"key":"ref19","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1111\/j.1365-2303.2012.00993.x","article-title":"Cytological findings in urothelial carcinoma of the bladder with trophoblastic differentiation","volume":"24","author":"20 Kinoshita","year":"2013","unstructured":"20 Kinoshita Y, Takasu K, Yuri T, et al. 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Histologic pattern resembling ovarian papillary serous carcinoma. Am J Surg Pathol. 1994; 18: 1224-1232.","journal-title":"Am J Surg Pathol"},{"key":"ref25","doi-asserted-by":"publisher","first-page":"1798","DOI":"10.1016\/S0022-5347(05)68807-6","article-title":"Micropapillary bladder carcinoma: a clinicopathological study of 20 cases","volume":"161","author":"26 Johansson","year":"1999","unstructured":"26 Johansson SL, Borghede G, Holm\u00e4ng S. Micropapillary bladder carcinoma: a clinicopathological study of 20 cases. J Urol. 1999; 161: 1798-1802.","journal-title":"J Urol"},{"key":"ref26","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1007\/s11912-022-01219-x","article-title":"Clinicopathological review of micropapillary urothelial carcinoma","volume":"24","author":"Kumar D","year":"2022","unstructured":"27 Kumar D, Adeniran AJ. Clinicopathological review of micropapillary urothelial carcinoma. 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Eur Urol Oncol. 2021; 4: 510-514.","DOI":"10.1016\/j.euo.2019.06.012"},{"key":"ref31","doi-asserted-by":"publisher","first-page":"1207","DOI":"10.1016\/0046-8177(95)90195-7","article-title":"Epstein-Barr virus is detected in undifferentiated nasopharyngeal carcinoma but not in lymphoepithelioma-like carcinoma of the urinary bladder","volume":"26","author":"32 Gulley","year":"1995","unstructured":"32 Gulley ML, Amin MB, Nicholls JM, et al. Epstein-Barr virus is detected in undifferentiated nasopharyngeal carcinoma but not in lymphoepithelioma-like carcinoma of the urinary bladder. 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[H\u00fagyh\u00f3lyagtumorok patol\u00f3gi\u00e1ja, sz\u00f6vettani diagn\u00f3zis\u00e1nak szempontjai, lehet\u0151s\u00e9gei \u00e9s elv\u00e1r\u00e1sai (TUR, cisztekt\u00f3mia).] Magy Onkol. 2021; 65: 291-300. [Hungarian]"},{"key":"ref42","doi-asserted-by":"publisher","first-page":"111","DOI":"10.1002\/dc.24331","article-title":"Cytological features of micropapillary and plasmacytoid variants of urothelial carcinoma","volume":"48","author":"43 Straccia","year":"2020","unstructured":"43 Straccia P, Martini M, Sacco E, et al. Cytological features of micropapillary and plasmacytoid variants of urothelial carcinoma. Diagn Cytopathol. 2020; 48: 111-117.","journal-title":"Diagn Cytopathol"},{"key":"ref43","doi-asserted-by":"publisher","first-page":"1923","DOI":"10.1016\/j.juro.2008.07.035","article-title":"Plasmacytoid urothelial carcinoma of the bladder: histological and clinical features of 5 cases","volume":"180","author":"44 Fritsche","year":"2008","unstructured":"44 Fritsche HM, Burger M, Denzinger S, et al. Plasmacytoid urothelial carcinoma of the bladder: histological and clinical features of 5 cases. J Urol. 2008; 180: 1923-1927.","journal-title":"J Urol"},{"key":"ref44","doi-asserted-by":"publisher","first-page":"794563","DOI":"10.1155\/2014\/794563","article-title":"Sarcomatoid variant of urothelial carcinoma (carcinosarcoma, spindle cell carcinoma): a review of the literature","volume":"2014","author":"Venyo AK","year":"2014","unstructured":"45 Venyo AK, Titi S. Sarcomatoid variant of urothelial carcinoma (carcinosarcoma, spindle cell carcinoma): a review of the literature. ISRN Urol. 2014; 2014: 794563.","journal-title":"ISRN Urol"},{"key":"ref45","doi-asserted-by":"publisher","first-page":"49","DOI":"10.3892\/ol.2012.990","article-title":"Sarcomatoid variant of urothelial carcinoma: cytological analysis of three cases","volume":"5","author":"46 Arita","year":"2013","unstructured":"46 Arita N, Ishida M, Yoshida K, et al. Sarcomatoid variant of urothelial carcinoma: cytological analysis of three cases. Oncol Lett. 2013; 5: 49-52.","journal-title":"Oncol Lett"},{"key":"ref46","doi-asserted-by":"publisher","unstructured":"47 Wright JL, Black PC, Brown GA, et al. Differences in survival among patients with sarcomatoid carcinoma, carcinosarcoma and urothelial carcinoma of the bladder. J Urol. 2007; 178: 2302-2306; discussion 2307.","DOI":"10.1016\/j.juro.2007.08.038"},{"key":"ref47","doi-asserted-by":"publisher","unstructured":"48 Chaudhary K, Pareek T, Sharma A, et al. Lipid-rich variant of urothelial carcinoma: a lethal enigma. BMJ Case Rep. 2021; 14: e240593.","DOI":"10.1136\/bcr-2020-240593"},{"key":"ref48","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1016\/j.path.2015.07.004","article-title":"Diagnosis of bladder carcinoma: a clinician's perspective","volume":"8","author":"49 Harshman","year":"2015","unstructured":"49 Harshman LC, Preston MA, Bellmunt J, et al. Diagnosis of bladder carcinoma: a clinician's perspective. Surg Pathol Clin. 2015; 8: 677-685.","journal-title":"Surg Pathol Clin"},{"key":"ref49","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1007\/s11255-020-02725-2","article-title":"Clear cell carcinoma of the urinary bladder: a systematic review","volume":"53","author":"50 Chan","year":"2021","unstructured":"50 Chan EO, Chan VW, Poon JY, et al. Clear cell carcinoma of the urinary bladder: a systematic review. Int Urol Nephrol. 2021; 53: 815-824.","journal-title":"Int Urol Nephrol"},{"key":"ref50","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1007\/s12253-016-0179-x","article-title":"Prognostic factors for renal cell carcinoma subtypes diagnosed according to the 2016 WHO renal tumor classification: a study involving 928 patients","volume":"23","author":"51 Kuthi","year":"2017","unstructured":"51 Kuthi L, Jenei A, Hajdu A, et al. Prognostic factors for renal cell carcinoma subtypes diagnosed according to the 2016 WHO renal tumor classification: a study involving 928 patients. Pathol Oncol Res. 2017; 23: 689-698.","journal-title":"Pathol Oncol Res"},{"key":"ref51","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1111\/his.12785","article-title":"Pleomorphic giant cell carcinoma of the urinary bladder: an extreme form of tumour de-differentiation","volume":"68","author":"52 Samaratunga","year":"2016","unstructured":"52 Samaratunga H, Delahunt B, Egevad L, et al. Pleomorphic giant cell carcinoma of the urinary bladder: an extreme form of tumour de-differentiation. Histopathology 2016; 68: 533-540.","journal-title":"Histopathology"},{"key":"ref52","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1038\/modpathol.3800521","article-title":"Osteoclast-rich undifferentiated carcinomas of the urinary tract","volume":"19","author":"53 Baydar","year":"2006","unstructured":"53 Baydar D, Amin MB, Epstein JI. Osteoclast-rich undifferentiated carcinomas of the urinary tract. Mod Pathol. 2006; 19: 161-171.","journal-title":"Mod Pathol"},{"key":"ref53","doi-asserted-by":"publisher","unstructured":"54 Fazekas F, B\u00edr\u00f3 K, \u00c1goston P, et al. The first experience in Hungary with split-course multimodal treatment in high risk bladder cancer. [Az osztott d\u00f3zis\u00fa trimod\u00e1lis kezel\u00e9s els\u0151 hazai alkalmaz\u00e1sa nagy kock\u00e1zat\u00fa h\u00fagyh\u00f3lyagdaganat eset\u00e9ben.] Orv Hetil. 2021; 162: 2017-2022. [Hungarian]","DOI":"10.1556\/650.2021.32224"},{"key":"ref54","unstructured":"55 Gontero P, Comp\u00e9rat E, Dominguez Escrig JL, et al. Non-muscle-invasive bladder cancer (TaT1 and CIS). EAU guidelines. Edn. presented at the EAU Annual Congress Milan 2023. European Association of Urology, 2023. ISBN 978-94-92671-19-6."},{"key":"ref55","unstructured":"56 Witjes JA, Bruins HM, Carri\u00f3n A, et al. EAU guidelines on muscle-invasive and metastatic bladder cancer. Edn. presented at the EAU Annual Congress Milan 2023. European Association of Urology, 2023. ISBN 978-94-92671-19-6."},{"key":"ref56","unstructured":"57 G\u00e9czi L, Dienes T, K\u00fcronya Z, et al. Immunotherapy in advanced urothelial cancer. [Az immunter\u00e1pia helye az el\u0151rehaladott uroteli\u00e1lis daganatok els\u0151-, m\u00e1sod \u00e9s t\u00f6bbedvonalbeli kezel\u00e9s\u00e9ben. Magy Onkol. 2021; 65: 339-346. [Hungarian]"},{"key":"ref57","doi-asserted-by":"publisher","first-page":"1611077","DOI":"10.3389\/pore.2023.1611077","article-title":"Correlation between fibroblast growth factor receptor mutation, programmed death ligand-1 expression and survival in urinary bladder cancer based on real-world data","volume":"29","author":"58 R\u00e9v\u00e9sz","year":"2023","unstructured":"58 R\u00e9v\u00e9sz J, Posfai B, Pajor L, et al. Correlation between fibroblast growth factor receptor mutation, programmed death ligand-1 expression and survival in urinary bladder cancer based on real-world data. Pathol Oncol Res. 2023; 29: 1611077.","journal-title":"Pathol Oncol Res"},{"key":"ref58","doi-asserted-by":"publisher","first-page":"1268","DOI":"10.6004\/jnccn.2017.7027","article-title":"Clinical significance of histologic variants of bladder cancer","volume":"15","author":"59 Warrick","year":"2017","unstructured":"59 Warrick JI. Clinical significance of histologic variants of bladder cancer. J Natl Compr Canc Netw. 2017; 15: 1268-1274.","journal-title":"J Natl Compr Canc Netw"},{"key":"ref59","doi-asserted-by":"publisher","unstructured":"60 Moschini M, Shariat SF, Lucian\u00f2 R, et al. Pure but not mixed histologic variants are associated with poor survival at radical cystectomy in bladder cancer patients. Clin Genitourin Cancer 2017; 15: e603-e607.","DOI":"10.1016\/j.clgc.2016.12.006"},{"key":"ref60","doi-asserted-by":"publisher","first-page":"5222","DOI":"10.1002\/cam4.5324","article-title":"Predictive value of molecular subtypes and APOBEC3G for adjuvant chemotherapy in urothelial bladder cancer","volume":"12","author":"61 Ol\u00e1h","year":"2023","unstructured":"61 Ol\u00e1h C, Reis H, Hoffmann MJ, et al. Predictive value of molecular subtypes and APOBEC3G for adjuvant chemotherapy in urothelial bladder cancer. Cancer Med. 2023; 12: 5222-5232.","journal-title":"Cancer Med"},{"key":"ref61","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1007\/978-1-0716-3291-8_2","article-title":"A panel-based method for the reproduction of distinct molecular subtype classifications of muscle-invasive urothelial bladder cancer","volume":"2684","author":"Ol\u00e1h C","year":"2023","unstructured":"62 Ol\u00e1h C, Szarvas T. A panel-based method for the reproduction of distinct molecular subtype classifications of muscle-invasive urothelial bladder cancer. Methods Mol Biol. 2023; 2684: 27-43.","journal-title":"Methods Mol Biol"},{"key":"ref62","doi-asserted-by":"publisher","unstructured":"63 Szarvas T, Ol\u00e1h Cs, Riesz P, et al. Molecular subtype classification of urothelial bladder cancer and its clinical relevance. [A h\u00fagyh\u00f3lyag urothelialis daganatainak molekul\u00e1ris alcsoportbeoszt\u00e1sa \u00e9s annak klinikai vonatkoz\u00e1sai.] Orv Hetil. 2019; 160: 1647-1654. 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