{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T23:06:09Z","timestamp":1784934369807,"version":"3.55.0"},"reference-count":40,"publisher":"Akademiai Kiado Zrt.","issue":"51","license":[{"start":{"date-parts":[[2023,12,24]],"date-time":"2023-12-24T00:00:00Z","timestamp":1703376000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2023,12,24]]},"abstract":"<jats:p>B\u00e1r a fi\u00fagyermekeket, illetve a fertilis kor\u00fa f\u00e9rfiakat \u00e9rint\u0151 daganatos\n                    megbeteged\u00e9sek sz\u00e1ma vil\u00e1gszerte emelkedik, az onkol\u00f3giai kezel\u00e9sek\n                    eredm\u00e9nyess\u00e9ge folyamatosan javul. Ennek k\u00f6vetkezt\u00e9ben jelent\u0151sen\n                    fel\u00e9rt\u00e9kel\u0151d\u00f6tt a ter\u00e1pi\u00e1t k\u00f6vet\u0151 \u00e9letmin\u0151s\u00e9g, \u00e9s ezen bel\u00fcl, kiemelten, a\n                    nemz\u0151k\u00e9pess\u00e9g meg\u0151rz\u00e9se. Magyarorsz\u00e1gon m\u00e9g nem \u00e1ll rendelkez\u00e9sre egys\u00e9ges\n                    fertilit\u00e1sprezerv\u00e1ci\u00f3s szakmai ir\u00e1nyelv, betegir\u00e1ny\u00edt\u00e1si rendszer \u00e9s dedik\u00e1lt\n                    infrastrukt\u00fara. A szerz\u0151k \u00e1ttekintik a legfrissebb, ir\u00e1nyad\u00f3 nemzetk\u00f6zi \u00e9s hazai\n                    szakirodalmi adatokat, \u00e9s elemzik az \u00e9rintett szakter\u00fcleteken szerzett hazai\n                    tapasztalatokat. Ezek ismeret\u00e9ben \u00edrnak a fi\u00fagyermekek \u00e9s a fertilis kor\u00fa\n                    f\u00e9rfiak onkol\u00f3giai kezel\u00e9s\u00e9nek fertilit\u00e1si kock\u00e1zatair\u00f3l, a sz\u00e1mukra el\u00e9rhet\u0151\n                    nemz\u0151k\u00e9pess\u00e9gi prezerv\u00e1ci\u00f3s m\u00f3dszerekr\u0151l, k\u00fcl\u00f6n kit\u00e9rve a prae-, illetve\n                    peripubertas-kor\u00fa fi\u00fakra, valamint a heredaganatok eset\u00e9n alkalmazhat\u00f3\n                    elj\u00e1r\u00e1sokra. Eredm\u00e9nyeik multidiszciplin\u00e1ris szeml\u00e9letet t\u00fckr\u00f6z\u0151 ismertet\u00e9se\n                    szakmai aj\u00e1nl\u00e1s alapj\u00e1t k\u00e9pezheti. Pubertas ut\u00e1ni \u00e9letkor\u00fa f\u00e9rfiakn\u00e1l a\n                    fertilit\u00e1s meg\u0151rz\u00e9s\u00e9nek leghat\u00e9konyabb m\u00f3dja az onkol\u00f3giai kezel\u00e9st megel\u0151z\u0151\n                    spermium-m\u00e9lyfagyaszt\u00e1s, melyet ejakul\u00e1ci\u00f3s k\u00e9ptelens\u00e9g eset\u00e9n assziszt\u00e1lt\n                    ejakul\u00e1ci\u00f3s technik\u00e1k vagy seb\u00e9szi spermiumnyer\u00e9s eg\u00e9sz\u00edthet ki. Adolescens kor\u00fa\n                    f\u00e9rfiakn\u00e1l is lehet spermium-m\u00e9lyfagyaszt\u00e1s, de ez a mintaad\u00e1s miatt sokszor\n                    neh\u00e9zs\u00e9gbe \u00fctk\u00f6zik. Ilyen esetekben, illetve prae- vagy peripubertaskorban\n                    (ejakul\u00e1ci\u00f3 hi\u00e1ny\u00e1ban) m\u0171t\u00e9ti \u00faton nyert h\u00edmivarsejtek vagy spermatogenetikus\n                    \u0151ssejtek krioprezerv\u00e1ci\u00f3ja v\u00e9gezhet\u0151. A spermatogenetikus \u0151ssejtek\n                    vonatkoz\u00e1s\u00e1ban a k\u00e9s\u0151bbi felhaszn\u00e1l\u00e1s lehet\u0151s\u00e9gei jelenleg experiment\u00e1lis\n                    jelleg\u0171ek. Speci\u00e1lis megk\u00f6zel\u00edt\u00e9st ig\u00e9nyelnek a heredaganatos p\u00e1ciensek.\n                    Meg\u00e1llap\u00edt\u00e1saik alapj\u00e1n egy\u00e9rtelm\u0171en sz\u00fcks\u00e9ges egy egys\u00e9ges szakmai ir\u00e1nyelv\n                    szerint, az androl\u00f3giai \u00e9s onkol\u00f3giai team szoros egy\u00fcttm\u0171k\u00f6d\u00e9s\u00e9n alapul\u00f3\n                    fertilit\u00e1sprezerv\u00e1ci\u00f3s rendszer kialak\u00edt\u00e1sa, amelyhez a megfelel\u0151 hely\n                    biztos\u00edt\u00e1sa, a hum\u00e1ner\u0151forr\u00e1s k\u00e9pz\u00e9se mellett az infrastruktur\u00e1lis,\n                    finansz\u00edroz\u00e1si \u00e9s jogi k\u00f6rnyezet megteremt\u00e9se is sz\u00fcks\u00e9ges. Tekintve, hogy\n                    haz\u00e1nkban az onkol\u00f3giai kezel\u00e9sre szorul\u00f3 fi\u00fagyermekek \u00e9s fertilis kor\u00fa f\u00e9rfiak\n                    nemz\u0151k\u00e9pess\u00e9g-meg\u0151rz\u00e9s\u00e9nek m\u00e9rt\u00e9ke elmarad az ide\u00e1list\u00f3l, egy\u00e9ni \u00e9s t\u00e1rsadalmi\n                    szempontb\u00f3l is kiemelten fontos, hogy a legkorszer\u0171bb elj\u00e1r\u00e1sokhoz az \u00e9rintett\n                    betegek megfelel\u0151 helyen \u00e9s m\u00f3don hozz\u00e1f\u00e9rjenek. Orv Hetil. 2023; 164(51):\n                    2016\u20132023.<\/jats:p>","DOI":"10.1556\/650.2023.32953","type":"journal-article","created":{"date-parts":[[2024,1,3]],"date-time":"2024-01-03T16:55:15Z","timestamp":1704300915000},"page":"2016-2023","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":1,"title":["Gyermek- \u00e9s feln\u0151ttkor\u00fa daganatos f\u00e9rfiak nemz\u0151k\u00e9pess\u00e9g\u00e9nek meg\u0151rz\u00e9se"],"prefix":"10.1556","volume":"164","author":[{"given":"D\u00f3ra","family":"Vesztergom","sequence":"first","affiliation":[{"name":"Orsz\u00e1gos K\u00f3rh\u00e1zi F\u0151igazgat\u00f3s\u00e1g, Hum\u00e1n Reprodukci\u00f3s Igazgat\u00f3s\u00e1g Budapest Magyarorsz\u00e1g"},{"name":"Szegedi Tudom\u00e1nyegyetem, Szent-Gy\u00f6rgyi Albert Orvostudom\u00e1nyi Kar, Klinikai Orvostudom\u00e1nyi Doktori Iskola Szeged Magyarorsz\u00e1g"},{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Sz\u00fcl\u00e9szeti \u00e9s N\u0151gy\u00f3gy\u00e1szati Klinika, Assziszt\u00e1lt Reprodukci\u00f3s Centrum Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tam\u00e1s","family":"Tak\u00e1cs","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Sz\u00fcl\u00e9szeti \u00e9s N\u0151gy\u00f3gy\u00e1szati Klinika, Assziszt\u00e1lt Reprodukci\u00f3s Centrum Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krisztina","family":"B\u00edr\u00f3","sequence":"additional","affiliation":[{"name":"Orsz\u00e1gos Onkol\u00f3giai Int\u00e9zet Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Csaba","family":"Polg\u00e1r","sequence":"additional","affiliation":[{"name":"Orsz\u00e1gos Onkol\u00f3giai Int\u00e9zet Budapest Magyarorsz\u00e1g"},{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Onkol\u00f3giai Tansz\u00e9k Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Kr\u00e1di","sequence":"additional","affiliation":[{"name":"Orsz\u00e1gos K\u00f3rh\u00e1zi F\u0151igazgat\u00f3s\u00e1g, Hum\u00e1n Reprodukci\u00f3s Igazgat\u00f3s\u00e1g Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Szilvia","family":"Varga","sequence":"additional","affiliation":[{"name":"Orsz\u00e1gos Onkol\u00f3giai Int\u00e9zet, Sug\u00e1rter\u00e1pi\u00e1s K\u00f6zpont Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zolt\u00e1n","family":"Nov\u00e1k","sequence":"additional","affiliation":[{"name":"Orsz\u00e1gos Onkol\u00f3giai Int\u00e9zet, N\u0151gy\u00f3gy\u00e1szati Oszt\u00e1ly Budapest Magyarorsz\u00e1g"},{"name":"Szegedi Tudom\u00e1nyegyetem, Szent-Gy\u00f6rgyi Albert Orvostudom\u00e1nyi Kar, Klinikai Orvostudom\u00e1nyi Doktori Iskola Szeged Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zsolt","family":"Kopa","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Urol\u00f3giai Klinika, Androl\u00f3giai Centrum 1082 Budapest, Kor\u00e1nyi S. u. 2. 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