{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T00:55:41Z","timestamp":1785372941233,"version":"3.55.0"},"reference-count":20,"publisher":"Akademiai Kiado Zrt.","issue":"28","license":[{"start":{"date-parts":[[2024,7,14]],"date-time":"2024-07-14T00:00:00Z","timestamp":1720915200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"HUN-REN Hum\u00e1n Reprodukci\u00f3s Kutat\u00f3csoporth\u00e1l\u00f3zat","award":["RRF2.3.1-21-2022-00012"],"award-info":[{"award-number":["RRF2.3.1-21-2022-00012"]}]},{"DOI":"10.13039\/501100009615","name":"PTE \u00c1OK","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100009615","id-type":"DOI","asserted-by":"crossref"}]},{"name":"PTE Orvosi K\u00e9szs\u00e9gfejleszt\u0151 \u00e9s Innov\u00e1ci\u00f3s K\u00f6zpont"}],"content-domain":{"domain":["www.akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2024,7,14]]},"abstract":"\n Bevezet\u00e9s:<\/jats:italic>\n Az abszol\u00fat m\u00e9h eredet\u0171 infertilit\u00e1s \u00faj seb\u00e9szi\n kezel\u00e9si m\u00f3dszere az uterustranszplant\u00e1ci\u00f3.\n C\u00e9lkit\u0171z\u00e9s:<\/jats:italic>\n A hum\u00e1n\n m\u00e9h\u00e1t\u00fcltet\u00e9sre val\u00f3 felk\u00e9sz\u00fcl\u00e9s jegy\u00e9ben \u00e9l\u0151 donoros uterus-autotranszplant\u00e1ci\u00f3s\n m\u0171t\u00e9teket v\u00e9gezt\u00fcnk juhokban. A m\u0171t\u00e9tek c\u00e9lja az anat\u00f3miai k\u00e9pletek azonos\u00edt\u00e1sa,\n a graft el\u0151k\u00e9sz\u00edt\u00e9se be\u00fcltet\u00e9sre, az \u00e9rvarratok elv\u00e9gz\u00e9se \u00e9s a szakorvosi st\u00e1b\n csapatk\u00e9nt val\u00f3 munk\u00e1j\u00e1nak begyakorl\u00e1sa volt.\n M\u00f3dszer:<\/jats:italic>\n Az\n uterust ell\u00e1t\u00f3 ereket ered\u00e9s\u00fckig kiprepar\u00e1ltuk, majd hossz\u00fa vascularis ny\u00e9llel\n egy\u00fctt hysterectomi\u00e1t v\u00e9gezt\u00fcnk. Egy\u00f3r\u00e1s hidegischaemi\u00e1t k\u00f6vet\u0151en a\n n\u00e1trium-heparinos fiziol\u00f3gi\u00e1s s\u00f3oldattal perfund\u00e1lt szervet az azonos oldalra\n vissza\u00fcltett\u00fck, cervicovaginalis anastomosist \u00e9s \u201eend-to-side\u201d (v\u00e9g az oldalhoz)\n art\u00e9ri\u00e1s \u00e9s v\u00e9n\u00e1s anastomosist k\u00e9pezve az arteria iliaca externa el\u00fcls\u0151\n felsz\u00edn\u00e9re.\n Eredm\u00e9nyek:<\/jats:italic>\n A m\u0171t\u00e9tet 4 esetb\u0151l 2-ben sikeresnek\n min\u0151s\u00edtett\u00fck, mivel az autotranszplant\u00e1lt szerv a sz\u00edn\u00e9t, h\u0151m\u00e9rs\u00e9klet\u00e9t \u00e9s\n kering\u00e9s\u00e9t is teljes m\u00e9rt\u00e9kben visszanyerte. Az \u00e9letben maradt k\u00e9t \u00e1llaton\n ezut\u00e1n eutan\u00e1zi\u00e1t hajtottunk v\u00e9gre.\n Megbesz\u00e9l\u00e9s:<\/jats:italic>\n Az\n uterustranszplant\u00e1ci\u00f3s modell \u00faj perspekt\u00edv\u00e1t nyitott az abszol\u00fat m\u00e9h eredet\u0171\n infertilit\u00e1sban szenved\u0151 n\u0151k kezel\u00e9s\u00e9ben. A megfelel\u0151 felk\u00e9sz\u00fcl\u00e9s \u00e9s gyakorl\u00e1s\n nagy test\u0171 k\u00eds\u00e9rleti \u00e1llatokon elengedhetetlen. A k\u00eds\u00e9rletes\n uterustranszplant\u00e1ci\u00f3s juhmodell lehet\u0151s\u00e9get biztos\u00edt mind az \u00e9l\u0151 donoros, mind\n a cadaver donoros beavatkoz\u00e1sok gyakorl\u00e1s\u00e1ra.\n K\u00f6vetkeztet\u00e9s:<\/jats:italic>\n A\n juh k\u00eds\u00e9rletes \u00e9l\u0151 donoros \u00e1llatmodellt alkalmasnak tartjuk \u00e9s aj\u00e1nljuk a hum\u00e1n\n uterustranszplant\u00e1ci\u00f3ra val\u00f3 felk\u00e9sz\u00fcl\u00e9s c\u00e9lj\u00e1b\u00f3l. Orv Hetil. 2024; 165(28):\n 1079\u20131085.\n <\/jats:p>","DOI":"10.1556\/650.2024.33092","type":"journal-article","created":{"date-parts":[[2024,7,15]],"date-time":"2024-07-15T10:13:57Z","timestamp":1721038437000},"page":"1079-1085","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":4,"title":["A k\u00eds\u00e9rletes uterus-autotranszplant\u00e1ci\u00f3s juhmodell"],"prefix":"10.1556","volume":"165","author":[{"given":"B\u00e1lint","family":"Farkas","sequence":"first","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Sz\u00fcl\u00e9szeti \u00e9s N\u0151gy\u00f3gy\u00e1szati Klinika P\u00e9cs, \u00c9desany\u00e1k \u00fatja 17., 7624 Magyarorsz\u00e1g"},{"name":"Hum\u00e1n Reprodukci\u00f3s Nemzeti Laborat\u00f3rium, P\u00e9csi Tudom\u00e1nyegyetem P\u00e9cs Magyarorsz\u00e1g"},{"name":"HUN-REN\u2013PTE, Hum\u00e1n Reprodukci\u00f3s Kutat\u00f3csoport P\u00e9cs Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K\u00e1lm\u00e1n","family":"Kov\u00e1cs","sequence":"additional","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Sz\u00fcl\u00e9szeti \u00e9s N\u0151gy\u00f3gy\u00e1szati Klinika P\u00e9cs, \u00c9desany\u00e1k \u00fatja 17., 7624 Magyarorsz\u00e1g"},{"name":"Hum\u00e1n Reprodukci\u00f3s Nemzeti Laborat\u00f3rium, P\u00e9csi Tudom\u00e1nyegyetem P\u00e9cs Magyarorsz\u00e1g"},{"name":"HUN-REN\u2013PTE, Hum\u00e1n Reprodukci\u00f3s Kutat\u00f3csoport P\u00e9cs Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Szil\u00e1rd","family":"Kolumb\u00e1n","sequence":"additional","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Sz\u00fcl\u00e9szeti \u00e9s N\u0151gy\u00f3gy\u00e1szati Klinika P\u00e9cs, \u00c9desany\u00e1k \u00fatja 17., 7624 Magyarorsz\u00e1g"},{"name":"Hum\u00e1n Reprodukci\u00f3s Nemzeti Laborat\u00f3rium, P\u00e9csi Tudom\u00e1nyegyetem P\u00e9cs Magyarorsz\u00e1g"},{"name":"P\u00e9csi Tudom\u00e1nyegyetem, Eg\u00e9szs\u00e9gtudom\u00e1nyi Kar, Eg\u00e9szs\u00e9gtudom\u00e1nyi Doktori Iskola P\u00e9cs Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Rozanovic","sequence":"additional","affiliation":[{"name":"Hum\u00e1n Reprodukci\u00f3s Nemzeti Laborat\u00f3rium, P\u00e9csi Tudom\u00e1nyegyetem P\u00e9cs Magyarorsz\u00e1g"},{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Aneszteziol\u00f3giai \u00e9s Intenz\u00edv Ter\u00e1pi\u00e1s Int\u00e9zet P\u00e9cs Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Em\u0151ke","family":"Heged\u0171s","sequence":"additional","affiliation":[{"name":"Hum\u00e1n Reprodukci\u00f3s Nemzeti Laborat\u00f3rium, P\u00e9csi Tudom\u00e1nyegyetem P\u00e9cs Magyarorsz\u00e1g"},{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Aneszteziol\u00f3giai \u00e9s Intenz\u00edv Ter\u00e1pi\u00e1s Int\u00e9zet P\u00e9cs Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00e1bor","family":"Jancs\u00f3","sequence":"additional","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, \u00c9rseb\u00e9szeti Klinika P\u00e9cs Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f3zsef","family":"B\u00f3dis","sequence":"additional","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Sz\u00fcl\u00e9szeti \u00e9s N\u0151gy\u00f3gy\u00e1szati Klinika P\u00e9cs, \u00c9desany\u00e1k \u00fatja 17., 7624 Magyarorsz\u00e1g"},{"name":"Hum\u00e1n Reprodukci\u00f3s Nemzeti Laborat\u00f3rium, P\u00e9csi Tudom\u00e1nyegyetem P\u00e9cs Magyarorsz\u00e1g"},{"name":"HUN-REN\u2013PTE, Hum\u00e1n Reprodukci\u00f3s Kutat\u00f3csoport P\u00e9cs Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00e1bor","family":"Fazekas","sequence":"additional","affiliation":[{"name":"Hum\u00e1n Reprodukci\u00f3s Nemzeti Laborat\u00f3rium, P\u00e9csi Tudom\u00e1nyegyetem P\u00e9cs Magyarorsz\u00e1g"},{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, \u00c9rseb\u00e9szeti Klinika P\u00e9cs Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"R1","doi-asserted-by":"crossref","unstructured":"Sieunarine K, Zakaria FB, Boyle DC, et al. 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