{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T22:42:26Z","timestamp":1785537746796,"version":"3.56.0"},"reference-count":46,"publisher":"Akademiai Kiado Zrt.","issue":"33","license":[{"start":{"date-parts":[[2024,8,18]],"date-time":"2024-08-18T00:00:00Z","timestamp":1723939200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Fels\u0151oktat\u00e1si Int\u00e9zm\u00e9nyi Kiv\u00e1l\u00f3s\u00e1gi Program"},{"name":"Transzl\u00e1ci\u00f3s Idegtudom\u00e1nyi Nemzeti Laborat\u00f3rium"}],"content-domain":{"domain":["www.akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2024,8,18]]},"abstract":"<jats:p>A progressz\u00edv multifok\u00e1lis leukoencephalopathi\u00e1t a John Cunningham-v\u00edrus\n                    reaktiv\u00e1l\u00f3d\u00e1sa okozza, amely szinte kiz\u00e1r\u00f3lag immunhi\u00e1nyos betegekn\u00e9l fordul\n                    el\u0151. A betegs\u00e9g t\u00fcneteit els\u0151sorban a demyelinisati\u00f3s g\u00f3cok lokaliz\u00e1ci\u00f3ja\n                    hat\u00e1rozza meg; a betegs\u00e9g a kezdeti szakaszban t\u00fcnetszeg\u00e9ny lehet, \u00e9s a\n                    neurol\u00f3giai t\u00fcnetek csak k\u00e9s\u0151bb jelennek meg. Diagnosztik\u00e1j\u00e1ban els\u0151sorban a\n                    k\u00e9palkot\u00f3 vizsg\u00e1latok \u00e9s a v\u00edrus-DNS liquorb\u00f3l t\u00f6rt\u00e9n\u0151 kimutat\u00e1sa j\u00e1tszik fontos\n                    szerepet. Specifikus ter\u00e1pi\u00e1ja nem ismert, a c\u00e9l az immunrendszer m\u0171k\u00f6d\u00e9s\u00e9nek\n                    helyre\u00e1ll\u00edt\u00e1sa. Kazuisztik\u00e1nkban egy pszichi\u00e1triai oszt\u00e1lyon \u00e9szlelt p\u00e1ciens\n                    k\u00f3rt\u00f6rt\u00e9net\u00e9t ismertetj\u00fck, akinek eset\u00e9ben AIDS-hez k\u00f6thet\u0151 jobb f\u00e9ltekei\n                    progressz\u00edv multifok\u00e1lis leukoencephalopathia k\u00e9pe igazol\u00f3dott. Korai\n                    differenci\u00e1ldiagnosztikai neh\u00e9zs\u00e9get jelentettek a p\u00e1ciensn\u00e9l \u00e9szlelhet\u0151\n                    patol\u00f3gi\u00e1s szem\u00e9lyis\u00e9gjegyek, illetve az \u00e9lethelyzeti neh\u00e9zs\u00e9gek \u00e9s a\n                    p\u00e1rkapcsolati vesztes\u00e9g talaj\u00e1n kialakult kr\u00edzis\u00e1llapot. Eset\u00fcnkkel szeretn\u00e9nk\n                    felh\u00edvni a figyelmet az immunhi\u00e1nyos betegekn\u00e9l jelentkez\u0151 pszichi\u00e1triai t\u00fcnetek\n                    fontoss\u00e1g\u00e1ra. Orv Hetil. 2024; 165(33): 1295\u20131302.<\/jats:p>","DOI":"10.1556\/650.2024.33102","type":"journal-article","created":{"date-parts":[[2024,8,19]],"date-time":"2024-08-19T11:31:24Z","timestamp":1724067084000},"page":"1295-1302","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":2,"title":["Pszichi\u00e1triai oszt\u00e1lyon diagnosztiz\u00e1lt, AIDS talaj\u00e1n kialakult progressz\u00edv multifok\u00e1lis leukoencephalopathia"],"prefix":"10.1556","volume":"165","author":[{"given":"Csenge","family":"Lovig","sequence":"first","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Klinikai K\u00f6zpont, Pszichi\u00e1triai \u00e9s Pszichoter\u00e1pi\u00e1s Klinika P\u00e9cs, R\u00e9t u. 2., 7623 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R\u00f3bert","family":"Herold","sequence":"additional","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Klinikai K\u00f6zpont, Pszichi\u00e1triai \u00e9s Pszichoter\u00e1pi\u00e1s Klinika P\u00e9cs, R\u00e9t u. 2., 7623 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Endre","family":"P\u00e1l","sequence":"additional","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Klinikai K\u00f6zpont, Neurol\u00f3giai Klinika P\u00e9cs Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Be\u00e1ta","family":"B\u00f3n\u00e9","sequence":"additional","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Klinikai K\u00f6zpont, Neurol\u00f3giai Klinika P\u00e9cs Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e9la","family":"Faludi","sequence":"additional","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Klinikai K\u00f6zpont, Neurol\u00f3giai Klinika P\u00e9cs Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"No\u00e9mi","family":"Albert","sequence":"additional","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Klinikai K\u00f6zpont, Pszichi\u00e1triai \u00e9s Pszichoter\u00e1pi\u00e1s Klinika P\u00e9cs, R\u00e9t u. 2., 7623 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dominik","family":"Dibusz","sequence":"additional","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Klinikai K\u00f6zpont, Pszichi\u00e1triai \u00e9s Pszichoter\u00e1pi\u00e1s Klinika P\u00e9cs, R\u00e9t u. 2., 7623 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriella","family":"Hern\u00e1di","sequence":"additional","affiliation":[{"name":"P\u00e9csi Diagnosztikai K\u00f6zpont P\u00e9cs Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zolt\u00e1n","family":"P\u00e9terfi","sequence":"additional","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Klinikai K\u00f6zpont I. 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