{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T14:05:38Z","timestamp":1785161138040,"version":"3.55.0"},"reference-count":49,"publisher":"Akademiai Kiado Zrt.","issue":"36","license":[{"start":{"date-parts":[[2024,9,8]],"date-time":"2024-09-08T00:00:00Z","timestamp":1725753600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Eur\u00f3pai Uni\u00f3 Helyre\u00e1ll\u00edt\u00e1si \u00e9s Ellen\u00e1ll\u00f3k\u00e9pess\u00e9gi Eszk\u00f6z","award":["RRF-2.3.1-21-2022-00012"],"award-info":[{"award-number":["RRF-2.3.1-21-2022-00012"]}]},{"name":"Sz\u00e9chenyi Terv Plusz"}],"content-domain":{"domain":["www.akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2024,9,8]]},"abstract":"<jats:p>\n                    <jats:italic>Bevezet\u00e9s:<\/jats:italic>\n                    A WHO adatai szerint a feln\u0151ttkor\u00faak mintegy 17,5%-a\n                    k\u00fczd fertilit\u00e1si probl\u00e9m\u00e1kkal, mind a n\u0151k, mind a f\u00e9rfiak kb. egyform\u00e1n\n                    \u00e9rintettek. Az is megfigyelhet\u0151, hogy az elm\u00falt \u00e9vtizedek sor\u00e1n folyamatos\n                    emelked\u00e9s l\u00e1that\u00f3 a medd\u0151s\u00e9gi kezel\u00e9sre szorul\u00f3k sz\u00e1m\u00e1ban, s ez a tendencia\n                    sokkal jobban \u00e9rinti a fejlett\/iparosodott orsz\u00e1gokat. Ezekben az \u00e9vtizedekben\n                    \u00e9letk\u00f6r\u00fclm\u00e9nyeink is \u00e1talakultak, ami t\u00f6bb ponton is kapcsolatba hozhat\u00f3 a medd\u0151\n                    kapcsolatok sz\u00e1m\u00e1nak n\u00f6veked\u00e9s\u00e9vel.\n                    <jats:italic>C\u00e9lkit\u0171z\u00e9s:<\/jats:italic>\n                    A\n                    szakirodalomb\u00f3l tudjuk, hogy a t\u00fals\u00faly, a doh\u00e1nyz\u00e1s, az alkoholfogyaszt\u00e1s, a\n                    nagym\u00e9rt\u00e9k\u0171 kezeletlen stressz \u00e9s ak\u00e1r a t\u00falzott vitaminfogyaszt\u00e1s is k\u00e9pes\n                    negat\u00edvan befoly\u00e1solni fertilit\u00e1si es\u00e9lyeinket. Tanulm\u00e1nyunk c\u00e9lja annak\n                    vizsg\u00e1lata, hogy a medd\u0151s\u00e9gi kezel\u00e9sben r\u00e9szt vev\u0151 p\u00e1rokn\u00e1l milyen m\u00e9rt\u00e9kben\n                    nyilv\u00e1nulnak meg a szakirodalomb\u00f3l ismert potenci\u00e1lisan k\u00e1ros \u00e9letviteli\n                    t\u00e9nyez\u0151k.\n                    <jats:italic>M\u00f3dszer:<\/jats:italic>\n                    Vizsg\u00e1latunk sor\u00e1n az int\u00e9zet\u00fcnkben 2020 \u00e9s\n                    2021 k\u00f6z\u00f6tt\n                    <jats:italic>in vitro<\/jats:italic>\n                    fertiliz\u00e1ci\u00f3s beavatkoz\u00e1sra jelentkez\u0151\n                    p\u00e1rokn\u00e1l m\u00e9rt\u00fck fel \u00e9letviteli szok\u00e1saikat, \u00e9s eredm\u00e9nyeinket le\u00edr\u00f3 jelleggel\n                    \u00f6sszehasonl\u00edtottuk a hazai statisztik\u00e1kkal. 200 p\u00e1r t\u00f6lt\u00f6tte ki a k\u00e9rd\u0151\u00edvet, a\n                    v\u00e1laszad\u00f3 n\u0151k \u00e9letkora 22\u201346 \u00e9v, a f\u00e9rfiak\u00e9 pedig 23\u201366 \u00e9v volt.\n                    <jats:italic>Eredm\u00e9nyek:<\/jats:italic>\n                    A v\u00e1laszad\u00f3 n\u0151k 45%-a, m\u00edg a f\u00e9rfiak 79,2%-a\n                    t\u00fals\u00falyos vagy elh\u00edzott. A n\u0151k 24%-a fogyaszt legal\u00e1bb heti egyszer alkoholt, a\n                    f\u00e9rfiaknak pedig az 54%-a. Rendszeresen doh\u00e1nyzik minden \u00f6t\u00f6dik n\u0151 (19%) \u00e9s\n                    minden negyedik f\u00e9rfi (26%). Mindezek mellett csak a v\u00e1laszad\u00f3k 21,5%-a sportol\n                    legal\u00e1bb heti 3 alkalommal. Felm\u00e9r\u00e9s\u00fcnk kit\u00e9rt p\u00e1cienseink stressz\u00e9rzet\u00e9re is. A\n                    r\u00e9szt vev\u0151 n\u0151k 27,8%-a \u00e9s a f\u00e9rfiak 12,5%-a vallotta mag\u00e1t depresszi\u00f3snak, m\u00edg a\n                    n\u0151k 41%-a \u00e9s a f\u00e9rfiak 15%-a fesz\u00fclt a gyermekv\u00e1llal\u00e1si neh\u00e9zs\u00e9gek miatt.\n                    <jats:italic>Megbesz\u00e9l\u00e9s \u00e9s k\u00f6vetkeztet\u00e9s:<\/jats:italic>\n                    Felm\u00e9r\u00e9s\u00fcnk szerint a\n                    szakirodalomban r\u00e9szletesen taglalt \u00e9letviteli kock\u00e1zati t\u00e9nyez\u0151k a mi\n                    p\u00e1cienseink \u00e9let\u00e9ben is jellemz\u0151ek, s ez j\u00f3l jelzi az eg\u00e9szs\u00e9gtudatoss\u00e1gi,\n                    illetve csal\u00e1dtervez\u00e9si eduk\u00e1ci\u00f3 fontoss\u00e1g\u00e1t. A fenti t\u00e9nyez\u0151k hozz\u00e1j\u00e1rulhatnak\n                    az int\u00e9zet\u00fcnkben jelentkez\u0151k sz\u00edv- \u00e9s \u00e9rrendszeri, valamint diabetol\u00f3giai\n                    probl\u00e9m\u00e1ihoz. Az eredm\u00e9nyek ismeret\u00e9ben meglep\u0151 a betegek k\u00f6r\u00e9ben a nagyar\u00e1ny\u00fa\n                    z\u00f6lds\u00e9g- \u00e9s gy\u00fcm\u00f6lcsfogyaszt\u00e1s, valamint fontos kiemelni, hogy sokan alkalmaznak\n                    gyakorlatilag minden nap valamilyen vitamink\u00e9sz\u00edtm\u00e9nyt. \u00d6sszess\u00e9g\u00e9ben\n                    elmondhat\u00f3, hogy betegeinkn\u00e9l kedvez\u0151tlen eg\u00e9szs\u00e9g\u00fcgyi k\u00e9p tapasztalhat\u00f3, mely\n                    illeszkedik a hazai statisztik\u00e1k adataiba. Orv Hetil. 2024; 165(36):\n                    1423\u20131432.\n                  <\/jats:p>","DOI":"10.1556\/650.2024.33124","type":"journal-article","created":{"date-parts":[[2024,9,8]],"date-time":"2024-09-08T10:39:44Z","timestamp":1725791984000},"page":"1423-1432","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":3,"title":["Medd\u0151s\u00e9gi kezel\u00e9sben r\u00e9szt vev\u0151 n\u0151k \u00e9s f\u00e9rfiak \u00e9letviteli szok\u00e1sainak felm\u00e9r\u00e9se"],"prefix":"10.1556","volume":"165","author":[{"given":"G\u00e1bor","family":"M\u00e1t\u00e9","sequence":"first","affiliation":[{"name":"Pannon Reprodukci\u00f3s Int\u00e9zet Tapolca, Bart\u00f3k B\u00e9la u. 1\u20133., 8300 Magyarorsz\u00e1g"},{"name":"P\u00e9csi Tudom\u00e1nyegyetem, Hum\u00e1n Reprodukci\u00f3s Nemzeti Laborat\u00f3rium P\u00e9cs Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e1s","family":"Ball\u00f3","sequence":"additional","affiliation":[{"name":"Pannon Reprodukci\u00f3s Int\u00e9zet Tapolca, Bart\u00f3k B\u00e9la u. 1\u20133., 8300 Magyarorsz\u00e1g"},{"name":"P\u00e9csi Tudom\u00e1nyegyetem, Hum\u00e1n Reprodukci\u00f3s Nemzeti Laborat\u00f3rium P\u00e9cs Magyarorsz\u00e1g"},{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Urol\u00f3giai Klinika P\u00e9cs Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1rp\u00e1d","family":"Sz\u00e1nt\u00f3","sequence":"additional","affiliation":[{"name":"P\u00e9csi Tudom\u00e1nyegyetem, Hum\u00e1n Reprodukci\u00f3s Nemzeti Laborat\u00f3rium P\u00e9cs Magyarorsz\u00e1g"},{"name":"P\u00e9csi Tudom\u00e1nyegyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Urol\u00f3giai Klinika P\u00e9cs Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zsolt","family":"Kopa","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Urol\u00f3giai Klinika, Androl\u00f3giai Centrum Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Attila","family":"T\u00f6r\u00f6k","sequence":"additional","affiliation":[{"name":"Pannon Reprodukci\u00f3s Int\u00e9zet Tapolca, Bart\u00f3k B\u00e9la u. 1\u20133., 8300 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"R1","unstructured":"Kumar S, Thaker R, Verma V, et al. Occupational, environmental\n                    exposure and lifestyle factors: declining male reproductive health. J Gynecol\n                    Infertil. 2018; 1: 1\u201329."},{"key":"R2","doi-asserted-by":"crossref","unstructured":"Ilacqua A, Izzo G, Emerenziani GP, et al. Lifestyle and fertility:\n                    the influence of stress and quality of life on male fertility. Reprod Biol\n                    Endocrinol. 2018; 16: 115.","DOI":"10.1186\/s12958-018-0436-9"},{"key":"R3","unstructured":"Ikyernum JA, Agbecha A, Hwande ST. Semen profile of men presenting\n                    with infertility at First Fertility Hospital, Makurdi, North-Central Nigeria.\n                    Clin Med Diagn. 2019; 9: 26\u201335."},{"key":"R4","doi-asserted-by":"crossref","unstructured":"Silvestris E, Lovero D, Palmirotta R. Nutrition and female\n                    fertility: an independent correlation. Front Endocrinol. 2019; 10:\n                    346.","DOI":"10.3389\/fendo.2019.00346"},{"key":"R5","doi-asserted-by":"crossref","unstructured":"Herman T, Csehely Sz, Orosz M, et al. Prevalence and association of\n                    endocrine disorders in women participating in an in vitro\n                    fertilization program. [Endokrin k\u00f3rk\u00e9pek el\u0151fordul\u00e1sa \u00e9s t\u00e1rsul\u00e1sa in\n                        vitro fertiliz\u00e1ci\u00f3s programban r\u00e9szt vev\u0151 n\u0151k k\u00f6r\u00e9ben.] Orv Hetil.\n                    2022; 163: 712\u2013719. [Hungarian]","DOI":"10.1556\/650.2022.32372"},{"key":"R6","doi-asserted-by":"crossref","unstructured":"Ubaldi FM, Cimadomo D, Vaiarelli A, et al. Advanced maternal age in\n                    IVF: still a challenge? The present and the future of its treatment. 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[Hungarian]"},{"key":"R9","unstructured":"World Health Organization. Global Health Observatory data\n                    repository. Overweight\/Obesity. Available from:\n                        https:\/\/apps.who.int\/gho\/data\/view.main.REGION2480A?lang=en\n                    [accessed: 01. 06. 2024]."},{"key":"R10","doi-asserted-by":"crossref","unstructured":"Uddandrao VV, Brahma Naidu P, Chandrasekaran P, et al.\n                    Pathophysiology of obesity-related infertility and its prevention and treatment\n                    by potential phytotherapeutics. Int J Obes. 2024; 48: 147\u2013165.","DOI":"10.1038\/s41366-023-01411-4"},{"key":"R11","doi-asserted-by":"crossref","unstructured":"Racho\u0144 D, Teede H. Ovarian function and obesity \u2013 interrelationship,\n                    impact on women\u2019s reproductive lifespan and treatment options. 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Nat\n                    Rev Urol. 2015; 12: 373\u2013382.","DOI":"10.1038\/nrurol.2015.112"},{"key":"R44","doi-asserted-by":"crossref","unstructured":"Hou G, Xiong W, Wang M, et al. Chronic stress influences sexual\n                    motivation and causes damage to testicular cells in male rats. J Sex Med. 2014;\n                    11: 653\u2013663.","DOI":"10.1111\/jsm.12416"},{"key":"R45","unstructured":"Demirci T, Sahin E. The effect of chronic stress and obesity on\n                    sperm quality and testis histology in male rats; a morphometric and\n                    immunohistochemical study. Histol Histopathol. 2019; 34:\n                    287\u2013302."},{"key":"R46","doi-asserted-by":"crossref","unstructured":"Tohei A, Tomabechi T, Mamada M, et al. Effects of repeated ether\n                    stress on the hypothalamic-pituitary-testes axis in adult rats with special\n                    reference to inhibin secretion. 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