{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T11:03:11Z","timestamp":1785322991038,"version":"3.55.0"},"reference-count":39,"publisher":"Akademiai Kiado Zrt.","issue":"49","license":[{"start":{"date-parts":[[2024,12,8]],"date-time":"2024-12-08T00:00:00Z","timestamp":1733616000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100015763","name":"Szegedi Tudom\u00e1nyegyetem","doi-asserted-by":"crossref","award":["IV-134-62-12024.SZAOK"],"award-info":[{"award-number":["IV-134-62-12024.SZAOK"]}],"id":[{"id":"10.13039\/501100015763","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Kultur\u00e1lis \u00e9s Innov\u00e1ci\u00f3s Miniszt\u00e9rium","award":["\u00daNKP-23-4-SZTE-389"],"award-info":[{"award-number":["\u00daNKP-23-4-SZTE-389"]}]}],"content-domain":{"domain":["www.akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2024,12,8]]},"abstract":"\n Az adenosquamosus carcinoma az epeh\u00f3lyag-daganatok ritka alt\u00edpusa, amely a\n k\u00f6rnyez\u0151 anat\u00f3miai strukt\u00far\u00e1kra is gyakran r\u00e1terjed, valamint az epeh\u00f3lyag\n malignus tumoraihoz hasonl\u00f3an igen agressz\u00edv viselked\u00e9s\u0171. A munk\u00e1nkban\n bemutatott 70 \u00e9ves n\u0151betegn\u00e9l hasi f\u00e1jdalom miatt indult kivizsg\u00e1l\u00e1s, melynek\n sor\u00e1n k\u00e9palkot\u00f3 vizsg\u00e1lattal az epeh\u00f3lyagfal kisz\u00e9lesed\u00e9s\u00e9re der\u00fclt f\u00e9ny. Az\n epeh\u00f3lyagot a k\u00f6rnyez\u0151 m\u00e1jparenchym\u00e1val, valamint a\n per\n continuitatem<\/jats:italic>\n terjed\u00e9s miatt a szomsz\u00e9dos vastagb\u00e9llel egy\u00fctt\n elt\u00e1vol\u00edtott\u00e1k. A sz\u00f6vettani vizsg\u00e1lat epeh\u00f3lyag-kiindul\u00e1s\u00fa adenosquamosus\n carcinom\u00e1t igazolt. Az elszarusod\u00e1s jeleit is mutat\u00f3 laph\u00e1mcarcinom\u00e1s\n ter\u00fcleteken p40 immunhisztok\u00e9miai vizsg\u00e1lattal \u00e9szlelt\u00fcnk pozitivit\u00e1st. A\n diagn\u00f3zis fel\u00e1ll\u00edt\u00e1sa \u00f3ta eltelt 1 h\u00f3napban a beteg \u00e1llapota stabil volt,\n jelenleg adjuv\u00e1ns onkol\u00f3giai kezel\u00e9sben r\u00e9szes\u00fcl. A rendelkez\u00e9sre \u00e1ll\u00f3 irodalmi\n adatok alapj\u00e1n az epeh\u00f3lyag adenosquamosus carcinoma n\u0151i predominanci\u00e1t mutat, a\n 6\u20137. \u00e9vtizedben jelentkezik. Az els\u0151 t\u00fcnetk\u00e9nt a leggyakrabban hasi f\u00e1jdalom\n \u00e9szlelhet\u0151. A jelenlegi WHO-klasszifik\u00e1ci\u00f3 a laph\u00e1mcarcinom\u00e1s komponens ar\u00e1ny\u00e1t\n legal\u00e1bb 25%-ban \u00e1llap\u00edtja meg a sz\u00f6vettani vizsg\u00e1lat sor\u00e1n. A definit\u00edv\n diagn\u00f3zis fel\u00e1ll\u00edt\u00e1s\u00e1hoz sz\u00fcks\u00e9ges az \u00e1tt\u00e9ti folyamat kiz\u00e1r\u00e1sa. Orv Hetil. 2024;\n 165(49): 1945\u20131950.\n <\/jats:p>","DOI":"10.1556\/650.2024.33176","type":"journal-article","created":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T01:52:19Z","timestamp":1733709139000},"page":"1945-1950","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":1,"title":["Az epeh\u00f3lyag adenosquamosus daganata"],"prefix":"10.1556","volume":"165","author":[{"given":"Fanni","family":"Heged\u0171s","sequence":"first","affiliation":[{"name":"Szegedi Tudom\u00e1nyegyetem, Szent-Gy\u00f6rgyi Albert Orvostudom\u00e1nyi Kar, Pathologiai Int\u00e9zet Szeged, \u00c1llom\u00e1s u. 1., 6725 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita","family":"Sejben","sequence":"additional","affiliation":[{"name":"Szegedi Tudom\u00e1nyegyetem, Szent-Gy\u00f6rgyi Albert Orvostudom\u00e1nyi Kar, Pathologiai Int\u00e9zet Szeged, \u00c1llom\u00e1s u. 1., 6725 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"R1","unstructured":"The WHO Classification of Tumors Editorial Board. 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