{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T01:27:28Z","timestamp":1789694848932,"version":"4.0.1"},"reference-count":0,"publisher":"Akademiai Kiado Zrt.","issue":"51","license":[{"start":{"date-parts":[[2024,12,22]],"date-time":"2024-12-22T00:00:00Z","timestamp":1734825600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2024,12,22]]},"abstract":"<jats:p><jats:italic>Bevezet\u00e9s:<\/jats:italic> A SARS-CoV-2-fert\u0151z\u00e9s \u00e9s a lek\u00fczd\u00e9s\u00e9re bevezetett\n                    t\u00f6bbsz\u00f6ri v\u00e9d\u0151olt\u00e1sok kamp\u00e1nyai m\u00e9lyrehat\u00f3 v\u00e1ltoz\u00e1sokat okoztak egy adott\n                    orsz\u00e1g, ezen bel\u00fcl 1-1 sz\u0171kebb r\u00e9gi\u00f3 lakoss\u00e1g\u00e1nak eg\u00e9szs\u00e9gi \u00e1llapot\u00e1ban,\n                    valamint az immunrendszer m\u0171k\u00f6d\u00e9s\u00e9ben. <jats:italic>C\u00e9lkit\u0171z\u00e9s:<\/jats:italic>\n                    Vizsg\u00e1lataink c\u00e9lja megl\u00e9v\u0151, folyamatosan regisztr\u00e1lt dent\u00e1lis\n                    allergiavizsg\u00e1latok retrospekt\u00edv elemz\u00e9se volt a IV-es t\u00edpus\u00fa <jats:italic>in\n                        vivo<\/jats:italic> cellul\u00e1ris immunvizsg\u00e1latok egyik noninvaz\u00edv m\u00f3dszer\u00e9vel, az\n                    epicutan tesztel\u00e9ssel. V\u00e1laszt v\u00e1rtunk a pand\u00e9mia kiv\u00e1ltotta hat\u00e1sok\n                    tekintet\u00e9ben. <jats:italic>M\u00f3dszer:<\/jats:italic> \u00d6sszehasonl\u00edtottuk a\n                    COVID\u201319-fert\u0151z\u00e9shull\u00e1m el\u0151tti 4 \u00e9v \u00e9s a pand\u00e9mia 3 \u00e9ve alatti id\u0151szakot\n                    standard tesztsorokkal kapott nagysz\u00e1m\u00fa eredm\u00e9ny alapj\u00e1n 2 k\u00f6z\u00e9p-magyarorsz\u00e1gi\n                    vizsg\u00e1l\u00f3helyen, Budapesten 45 (2020 el\u0151tti) \u00e9s 45 (a 2020\u20132023. szeptember\n                    k\u00f6z\u00f6tti id\u0151szak) esetben. Fej\u00e9r v\u00e1rmegye sz\u00e9khely\u00e9n 48 COVID\u201319 el\u0151tti \u00e9s 55\n                    COVID\u201319 ut\u00e1ni, ugyancsak az \u00f6sszes megvizsg\u00e1lt szem\u00e9ly teszt pozit\u00edv\n                    eredm\u00e9nyeit elemezt\u00fck \u00e9s hasonl\u00edtottuk \u00f6ssze Pearson-f\u00e9le korrel\u00e1ci\u00f3val.\n                        <jats:italic>Eredm\u00e9nyek:<\/jats:italic> Az \u00e9szak-budapesti r\u00e9gi\u00f3ban v\u00e1rosi k\u00f3rh\u00e1zi\n                    szakambulanciai adatainak (11\u00a0781 egyedi teszt) megoszl\u00e1s\u00e1t vetett\u00fck \u00f6ssze a\n                    nyugat-magyarorsz\u00e1gi mag\u00e1norvosi laborat\u00f3rium eredm\u00e9nyeivel (14\u00a0716 egyedi\n                    teszt). A f\u00e9rfi-n\u0151 ar\u00e1ny mindk\u00e9t centrumban 1 : 5 k\u00f6r\u00fcli volt. Eredm\u00e9nyeink\n                    szerint a speci\u00e1lis c\u00e9lcsoportokon bel\u00fcl a vizsg\u00e1latok azonos m\u00f3dszer\u00e9vel \u00e9s 31\n                    k\u00f6zel azonos allerg\u00e9n tesztel\u00e9s\u00e9vel magasabb prevalenciaadatok nyerhet\u0151k, mint\n                    az \u00e1ltal\u00e1nos magyar k\u00f6rnyezeti epicutan tesztsorral, \u00edgy ez a m\u00f3dszer\n                    \u00e9rz\u00e9kenyebben k\u00f6vette a COVID\u201319-id\u0151szakban megjelen\u0151 v\u00e1ltoz\u00e1sokat. Eredm\u00e9nyeink\n                    mindk\u00e9t helyen a pand\u00e9mi\u00e1val \u00f6sszef\u00fcgg\u0151 t\u00f6bbsz\u00f6r\u00f6s szenzitiz\u00e1ci\u00f3fokoz\u00f3d\u00e1st\n                    mutattak, f\u0151k\u00e9nt a f\u00e9mallergi\u00e1k vonatkoz\u00e1s\u00e1ban. Kisebb m\u00e9rt\u00e9kben az akril\u00e1tokhoz\n                    k\u00f6thet\u0151 szenzitiz\u00e1ci\u00f3 hasonl\u00f3 eredm\u00e9nyeket adott. <jats:italic>Megbesz\u00e9l\u00e9s:<\/jats:italic>\n                    A k\u00e9t centrum k\u00f6z\u00fcl a nyugat-magyarorsz\u00e1gihoz volt illeszthet\u0151 a\n                    COVID\u201319-fert\u0151z\u00e9s \u00e1ltal el\u0151id\u00e9zett nagyobb morbidit\u00e1si \u00e9s mortalit\u00e1si adat.\n                    Ezzel p\u00e1rhuzamosan itt szenzitiz\u00e1ci\u00f3fokoz\u00f3d\u00e1st \u00e9szlelt\u00fcnk a fert\u0151tlen\u00edt\u0151kben \u00e9s\n                    arcmaszkokban jelen l\u00e9v\u0151 formaldehiddel, valamint az \u201eimmuner\u0151s\u00edt\u0151kben\u201d\n                    kiterjedten haszn\u00e1lt <jats:italic>Myroxylon pereirae<\/jats:italic> illat- \u00e9s \u00edzanyaggal\n                    (perubalzsammal). <jats:italic>K\u00f6vetkeztet\u00e9s:<\/jats:italic> A pand\u00e9mia hat\u00e1s\u00e1ra\n                    szignifik\u00e1nsan emelkedett a fog\u00e1szati anyagokkal szembeni cellul\u00e1ris\n                    hiperszenzitivit\u00e1s \u00e9s a t\u00f6bbsz\u00f6r\u00f6s pozitivit\u00e1s ar\u00e1nya. Az \u00e1ltalunk hozz\u00e1f\u00e9rhet\u0151\n                    szakirodalomban a COVID\u201319-fert\u0151z\u00e9s \u00e9s a dent\u00e1lis allergi\u00e1k kapcsolat\u00e1r\u00f3l nem\n                    tal\u00e1ltunk k\u00f6zl\u00e9st. Orv Hetil. 2024; 165(51): 2015\u20132025.<\/jats:p>","DOI":"10.1556\/650.2024.33187","type":"journal-article","created":{"date-parts":[[2024,12,31]],"date-time":"2024-12-31T08:53:37Z","timestamp":1735635217000},"page":"2015-2025","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":1,"title":["Epicutan pr\u00f3b\u00e1k fog\u00e1szati tesztsorokkal a COVID\u201319-j\u00e1rv\u00e1ny el\u0151tt \u00e9s alatt a K\u00f6z\u00e9p-Magyarorsz\u00e1g r\u00e9gi\u00f3ban"],"prefix":"10.1556","volume":"165","author":[{"given":"J. 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