{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T14:11:07Z","timestamp":1785420667551,"version":"3.56.0"},"reference-count":21,"publisher":"Akademiai Kiado Zrt.","issue":"2","license":[{"start":{"date-parts":[[2025,1,12]],"date-time":"2025-01-12T00:00:00Z","timestamp":1736640000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Kultur\u00e1lis \u00e9s Innov\u00e1ci\u00f3s Miniszt\u00e9rium","award":["\u00daNKP23-2"],"award-info":[{"award-number":["\u00daNKP23-2"]}]}],"content-domain":{"domain":["www.akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2025,1,12]]},"abstract":"<jats:p>\n                    <jats:italic>Bevezet\u00e9s:<\/jats:italic>\n                    A v\u00e9rszeg\u00e9nys\u00e9g a gyullad\u00e1sos b\u00e9lbetegs\u00e9gek egyik\n                    leggyakoribb sz\u00f6v\u0151dm\u00e9nye \u00e9s a betegs\u00e9g s\u00falyoss\u00e1g\u00e1nak egyik mutat\u00f3ja.\n                    <jats:italic>C\u00e9lkit\u0171z\u00e9s:<\/jats:italic>\n                    Vizsg\u00e1latunk c\u00e9lja az anaemia gyakoris\u00e1g\u00e1nak,\n                    etiol\u00f3gi\u00e1j\u00e1nak, predikt\u00edv t\u00e9nyez\u0151inek \u00e9s kezel\u00e9s\u00e9nek felm\u00e9r\u00e9se volt gyullad\u00e1sos\n                    b\u00e9lbetegs\u00e9gben szenved\u0151 betegeket kezel\u0151 k\u00e9t tercier centrum\n                    betegpopul\u00e1ci\u00f3j\u00e1ban.\n                    <jats:italic>M\u00f3dszer:<\/jats:italic>\n                    Retrospekt\u00edv, keresztmetszeti\n                    vizsg\u00e1latunkban egy\u00e9ves id\u0151szakban (2022. 06. 01. \u2013 2023. 05. 31.) a Semmelweis\n                    Egyetem k\u00e9t klinik\u00e1j\u00e1n megjelent betegek k\u00f6r\u00e9ben m\u00e9rt\u00fck fel az anaemia\n                    gyakoris\u00e1g\u00e1t, figyelembe v\u00e9ve az adott \u00e9vben el\u0151fordul\u00f3 legalacsonyabb\n                    hemoglobin\u00e9rt\u00e9ket. R\u00f6gz\u00edtett\u00fck a demogr\u00e1fiai adatokat, a betegs\u00e9gaktivit\u00e1st, a\n                    gy\u00f3gyszeres kezel\u00e9st, valamint a gyullad\u00e1sos markereket \u00e9s a vash\u00e1ztart\u00e1s\n                    laborat\u00f3riumi param\u00e9tereit. A klinikai betegs\u00e9gaktivit\u00e1st a\n                    Crohn-betegs\u00e9g-aktivit\u00e1si index \u00e9s a parci\u00e1lis Mayo-score seg\u00edts\u00e9g\u00e9vel\n                    hat\u00e1roztuk meg. Az anaemia s\u00falyoss\u00e1gi besorol\u00e1s\u00e1ban \u00e9s oszt\u00e1lyoz\u00e1s\u00e1ban az\n                    Eg\u00e9szs\u00e9g\u00fcgyi Vil\u00e1gszervezet \u00e1ll\u00e1sfoglal\u00e1sait vett\u00fck alapul. Az abszol\u00fat\n                    vashi\u00e1nyt &lt;30 \u00b5g\/l sz\u00e9rum-ferritin\u00e9rt\u00e9k eset\u00e9n, a kr\u00f3nikus betegs\u00e9gekhez\n                    t\u00e1rsul\u00f3 anaemi\u00e1t &gt;100 \u00b5g\/l ferritin\u00e9rt\u00e9k \u00e9s klinikai vagy biok\u00e9miai\n                    betegs\u00e9gaktivit\u00e1s jelenl\u00e9te eset\u00e9n defini\u00e1ltuk.\n                    <jats:italic>Eredm\u00e9nyek:<\/jats:italic>\n                    Vizsg\u00e1latunkba 400 beteget vontunk be (Crohn-beteg\/colitis ulcerosa: 277\/123). A\n                    Crohn-betegek 17,7%-a komplex (sztenotiz\u00e1l\u00f3\/penetr\u00e1l\u00f3) betegs\u00e9gviselked\u00e9ssel,\n                    m\u00edg a colitis ulceros\u00e1s betegek 40,7%-a extenz\u00edv vastagb\u00e9l-\u00e9rintetts\u00e9ggel volt\n                    jellemezhet\u0151. A betegek 75%-a biol\u00f3giai kezel\u00e9s alatt \u00e1llt. A betegpopul\u00e1ci\u00f3\n                    32,5%-\u00e1ban (n = 130) \u00e9szlelt\u00fcnk anaemi\u00e1t a vizsg\u00e1lt id\u0151szakban, melyek 57%-a\n                    enyhe, 35%-a k\u00f6zepes \u00e9s 8%-a s\u00falyos fok\u00fa volt. A nem macrocyt\u00e1s anaemi\u00e1kat (n =\n                    116) tov\u00e1bb vizsg\u00e1lva, a vash\u00e1ztart\u00e1sra vonatkoz\u00f3 adatok a betegek 51%-\u00e1ban (n =\n                    66) voltak el\u00e9rhet\u0151k. E betegek 73%-a szenvedett vashi\u00e1nyos anaemi\u00e1ban, 6%\n                    kr\u00f3nikus betegs\u00e9ghez t\u00e1rsul\u00f3 v\u00e9rszeg\u00e9nys\u00e9gben, illetve 17% funkcion\u00e1lis\n                    vashi\u00e1nnyal t\u00e1rsul\u00f3 kr\u00f3nikus betegs\u00e9ggel j\u00e1r\u00f3 anaemi\u00e1ban. Az anaemia prediktorai\n                    a szteroidkezel\u00e9s (p&lt;0,001; OR: 4,2), a klinikai (p&lt;0,001, OR: 3,8) \u00e9s a\n                    laborat\u00f3riumi betegs\u00e9gaktivit\u00e1s (p&lt;0,001, OR: 2,9) voltak.\n                    <jats:italic>K\u00f6vetkeztet\u00e9s:<\/jats:italic>\n                    A gyullad\u00e1sos b\u00e9lbetegs\u00e9gben szenved\u0151\n                    betegek k\u00f6r\u00e9ben gyakori a v\u00e9rszeg\u00e9nys\u00e9g, mely az esetek d\u00f6nt\u0151 t\u00f6bbs\u00e9g\u00e9ben\n                    vashi\u00e1nyos anaemia, \u00e9s szoros kapcsolatban \u00e1ll a betegs\u00e9gaktivit\u00e1ssal. Az\n                    anaemia felismer\u00e9se, oszt\u00e1lyoz\u00e1sa (a vash\u00e1ztart\u00e1s param\u00e9tereinek vizsg\u00e1lata) \u00e9s\n                    kezel\u00e9se kiemelten fontos a gyullad\u00e1sos b\u00e9lbetegs\u00e9gben szenved\u0151k k\u00f6r\u00e9ben. Orv\n                    Hetil. 2025; 166(2): 60\u201366.\n                  <\/jats:p>","DOI":"10.1556\/650.2025.33197","type":"journal-article","created":{"date-parts":[[2025,1,14]],"date-time":"2025-01-14T08:43:18Z","timestamp":1736844198000},"page":"60-66","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":0,"title":["Az anaemia gyakoris\u00e1g\u00e1nak felm\u00e9r\u00e9se, oszt\u00e1lyoz\u00e1sa, predikt\u00edv t\u00e9nyez\u0151i gyullad\u00e1sos b\u00e9lbetegs\u00e9gben szenved\u0151 betegekben"],"prefix":"10.1556","volume":"166","author":[{"given":"Fruzsina","family":"Balogh","sequence":"first","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Belgy\u00f3gy\u00e1szati \u00e9s Onkol\u00f3giai Klinika Budapest, Kor\u00e1nyi S. u. 2\/a, 1083 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorottya","family":"Angyal","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Belgy\u00f3gy\u00e1szati \u00e9s Onkol\u00f3giai Klinika Budapest, Kor\u00e1nyi S. u. 2\/a, 1083 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andor \u00c1ron","family":"Ecseki","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Belgy\u00f3gy\u00e1szati \u00e9s Onkol\u00f3giai Klinika Budapest, Kor\u00e1nyi S. u. 2\/a, 1083 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zs\u00f3fia Veronika","family":"Sebeszta","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Seb\u00e9szeti, Transzplant\u00e1ci\u00f3s \u00e9s Gasztroenterol\u00f3giai Klinika Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00f3r\u00e1nt","family":"G\u00f6nczi","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Belgy\u00f3gy\u00e1szati \u00e9s Onkol\u00f3giai Klinika Budapest, Kor\u00e1nyi S. u. 2\/a, 1083 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Livia","family":"Lontai","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Belgy\u00f3gy\u00e1szati \u00e9s Onkol\u00f3giai Klinika Budapest, Kor\u00e1nyi S. u. 2\/a, 1083 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u00e1l","family":"Miheller","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Seb\u00e9szeti, Transzplant\u00e1ci\u00f3s \u00e9s Gasztroenterol\u00f3giai Klinika Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P\u00e9ter","family":"Lakatos","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Belgy\u00f3gy\u00e1szati \u00e9s Onkol\u00f3giai Klinika Budapest, Kor\u00e1nyi S. u. 2\/a, 1083 Magyarorsz\u00e1g"},{"name":"Division of Gastroenterology, McGill University Health Centre Montreal Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1kos","family":"Ili\u00e1s","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Belgy\u00f3gy\u00e1szati \u00e9s Onkol\u00f3giai Klinika Budapest, Kor\u00e1nyi S. u. 2\/a, 1083 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"R1","doi-asserted-by":"crossref","unstructured":"Mahadea D, Adamczewska E, Ratajczak AE, et al. 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