{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T09:03:30Z","timestamp":1785488610544,"version":"3.56.0"},"reference-count":11,"publisher":"Akademiai Kiado Zrt.","issue":"4","content-domain":{"domain":["www.akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2025,1,26]]},"abstract":"<jats:p>\n                    A B\u00e1cs-Kiskun V\u00e1rmegyei Oktat\u00f3k\u00f3rh\u00e1z Gyermekoszt\u00e1ly\u00e1n 2023 tavasz\u00e1n egy h\u00f3napon\n                    bel\u00fcl n\u00e9gy s\u00falyos \u00e1llapot\u00fa gyermeket kezelt\u00fcnk, akikben a betegs\u00e9g h\u00e1tter\u00e9ben\n                    <jats:italic>Streptococcus pyogenes<\/jats:italic>\n                    fert\u0151z\u00e9s \u00e1llhatott. A k\u00f3rokoz\u00f3\n                    s\u00falyos, esetenk\u00e9nt \u00e9letvesz\u00e9lyes \u00e1llapotot okozott. A betegek \u2013 egy kiv\u00e9tel\u00e9vel\n                    \u2013 ugyanarr\u00f3l a telep\u00fcl\u00e9sr\u0151l \u00e9rkeztek, \u00edgy felmer\u00fclt ebben a k\u00f6z\u00f6ss\u00e9gben az\n                    invaz\u00edv kl\u00f3n terjed\u00e9s\u00e9nek lehet\u0151s\u00e9ge. Eseteinkben gyors klinikai \u00e1llapotroml\u00e1s\n                    volt megfigyelhet\u0151. A nemzetk\u00f6zi szakirodalomban is fellelhet\u0151 a k\u00fcl\u00f6nb\u00f6z\u0151,\n                    invaz\u00edv A-csoport\u00fa\n                    <jats:italic>Streptococcus<\/jats:italic>\n                    (iGAS-) fert\u0151z\u00e9sek id\u0151szakos\n                    halmoz\u00f3d\u00e1sa, melyek\u00e9rt k\u00fcl\u00f6nb\u00f6z\u0151 kl\u00f3nok felel\u0151sek. Megfigyelhet\u0151 ezen t\u00fal a\n                    k\u00fcl\u00f6nb\u00f6z\u0151 v\u00edruskoinfekci\u00f3k szerepe is. K\u00f6zlem\u00e9ny\u00fcnk c\u00e9lja felh\u00edvni a figyelmet\n                    az iGAS-fert\u0151z\u00e9sek jelent\u0151s\u00e9g\u00e9re, t\u00fcneteire, a szepszis korai felismer\u00e9s\u00e9nek\n                    fontoss\u00e1g\u00e1ra, valamint arra, hogy a betegek id\u0151ben a megfelel\u0151 progresszivit\u00e1si\n                    szint\u0171 int\u00e9zetbe ker\u00fcljenek. Orv Hetil. 2025; 166(4): 154\u2013159.\n                  <\/jats:p>","DOI":"10.1556\/650.2025.33204","type":"journal-article","created":{"date-parts":[[2025,2,14]],"date-time":"2025-02-14T09:16:22Z","timestamp":1739524582000},"page":"154-159","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":1,"title":["Streptococcus pyogenes okozta s\u00falyos fert\u0151z\u00e9sek halmoz\u00f3d\u00e1sa egy k\u00f3rh\u00e1zi gyermekoszt\u00e1lyra felvett betegek k\u00f6z\u00f6tt"],"prefix":"10.1556","volume":"166","author":[{"given":"Andrea","family":"L\u00e1bodi","sequence":"first","affiliation":[{"name":"B\u00e1cs-Kiskun V\u00e1rmegyei Oktat\u00f3k\u00f3rh\u00e1z, Csecsem\u0151- \u00e9s Gyermekgy\u00f3gy\u00e1szati Oszt\u00e1ly Kecskem\u00e9t, Ny\u00edri \u00fat 38., 6000 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T\u00fcnde","family":"Balogh","sequence":"additional","affiliation":[{"name":"B\u00e1cs-Kiskun V\u00e1rmegyei Oktat\u00f3k\u00f3rh\u00e1z, Csecsem\u0151- \u00e9s Gyermekgy\u00f3gy\u00e1szati Oszt\u00e1ly Kecskem\u00e9t, Ny\u00edri \u00fat 38., 6000 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e1nos","family":"Schnur","sequence":"additional","affiliation":[{"name":"Heim P\u00e1l Orsz\u00e1gos Gyermekgy\u00f3gy\u00e1szati Int\u00e9zet, Aneszteziol\u00f3giai \u00e9s Intenz\u00edv Ter\u00e1pi\u00e1s Oszt\u00e1ly Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gyula","family":"T\u00e1losi","sequence":"additional","affiliation":[{"name":"B\u00e1cs-Kiskun V\u00e1rmegyei Oktat\u00f3k\u00f3rh\u00e1z, Csecsem\u0151- \u00e9s Gyermekgy\u00f3gy\u00e1szati Oszt\u00e1ly Kecskem\u00e9t, Ny\u00edri \u00fat 38., 6000 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"425","reference":[{"key":"R1","doi-asserted-by":"crossref","unstructured":"Zhi X, Li HK, Li H, et al. Emerging invasive group A Streptococcus\n                        M1UK lineage detected by allele-specific PCR, England, 2020.\n                    Emerg Infect Dis. 2023; 29: 1007\u20131010.","DOI":"10.3201\/eid2905.221887"},{"key":"R2","doi-asserted-by":"crossref","unstructured":"Venturini C, Ong CY, Gillen CM, et al. Acquisition of the\n                    Sda1-encoding bacteriophage does not enhance virulence of the serotype M1\n                        Streptococcus pyogenes strain SF370. Infect Immun. 2013;\n                    81: 2062\u20132069.","DOI":"10.1128\/IAI.00192-13"},{"key":"R3","doi-asserted-by":"crossref","unstructured":"Lassoued Y, Assad Z, Ouldali N, et al. Unexpected increase in\n                    invasive group A streptococcal infections in children after respiratory viruses\n                    outbreak in France: a 15-year time-series analysis. Open Forum Infect Dis. 2023;\n                    10: ofad188.","DOI":"10.1093\/ofid\/ofad188"},{"key":"R4","doi-asserted-by":"crossref","unstructured":"Johannesen TB, Munkstrup C, Edslev SM, et al. Increase in invasive\n                    group A streptococcal infections and emergence of novel, rapidly expanding\n                    sub-lineage of the virulent Streptococcus pyogenes M1 clone,\n                    Denmark, 2023. Euro Surveill. 2023; 28: 2300291.","DOI":"10.2807\/1560-7917.ES.2023.28.26.2300291"},{"key":"R5","doi-asserted-by":"crossref","unstructured":"B\u00e9res A, Orb\u00e1n K, Szinku Zs, et al. Usage of high-flow oxygen\n                    therapy outside the intensive care unit: a possibility to delay or prevent the\n                    need for mechanical ventilation among COVID\u201319 patients. [Nagy \u00e1raml\u00e1s\u00fa\n                    oxig\u00e9nnel v\u00e9gzett ter\u00e1pia az intenz\u00edv oszt\u00e1ly keretein k\u00edv\u00fcl alkalmazva:\n                    lehet\u0151s\u00e9g a g\u00e9pi l\u00e9legeztet\u00e9s k\u00e9sleltet\u00e9s\u00e9re vagy elker\u00fcl\u00e9s\u00e9re COVID\u201319-ben].\n                    Orv Hetil. 2022; 163: 254\u2013266. [Hungarian]","DOI":"10.1556\/650.2022.32461"},{"key":"R6","unstructured":"American Family Physician. Diagnosis and treatment of streptococcal\n                    pharyngitis. Available from:\n                        https:\/\/www.aafp.org\/pubs\/afp\/issues\/2009\/0301\/p383.html\n                    [accessed: March 1, 2009]."},{"key":"R7","doi-asserted-by":"crossref","unstructured":"S\u00e1rga D, Bir\u00f3 L, Kiss-T\u00f3th B, et al. Nutrient intake and nutritional\n                    status of 4\u201310-year-old Hungarian children. [4\u201310 \u00e9ves magyar gyermekek\n                    t\u00e1panyagbeviteli \u00e9s t\u00e1pl\u00e1lts\u00e1gi \u00e1llapot\u00e1nak felm\u00e9r\u00e9se.] Orv Hetil. 2023; 164:\n                    533\u2013540. [Hungarian]","DOI":"10.1556\/650.2023.32713"},{"key":"R8","doi-asserted-by":"crossref","unstructured":"Cunningham MW. Pathogenesis of group A streptococcal infections.\n                    Clin Microbiol Rev. 2000; 13: 470\u2013511.","DOI":"10.1128\/CMR.13.3.470"},{"key":"R9","doi-asserted-by":"crossref","unstructured":"Tapiainen T, Launonen S, Renko M, et al. Invasive group A\n                    streptococcal infections in children: a nationwide survey in Finland. Pediatr\n                    Infect Dis J. 2016; 35: 123\u2013128.","DOI":"10.1097\/INF.0000000000000945"},{"key":"R10","doi-asserted-by":"crossref","unstructured":"Szab\u00f3 BG, Kiss R, L\u00e9n\u00e1rt KS, et al. \u201cTempus fugit, venit\n                        mors\u201d \u2013 about streptococcal toxic shock syndrome: a case report and\n                    mini-review. [\u201eTempus fugit, venit mors\u201d \u2013 a streptococcalis\n                    toxikus sokk szindr\u00f3m\u00e1r\u00f3l egy eset kapcs\u00e1n.] Orv Hetil. 2019; 160: 1887\u20131893.\n                    [Hungarian]","DOI":"10.1556\/650.2019.31597"},{"key":"R11","unstructured":"Health Alert Network (HAN). Increase in pediatric invasive group A\n                    streptococcal infections. Available from:\n                        https:\/\/emergency.cdc.gov\/han\/2022\/han00484.asp [accessed:\n                    December 22, 2022]."}],"container-title":["Orvosi Hetilap"],"original-title":[],"link":[{"URL":"https:\/\/www.akjournals.com\/view\/journals\/650\/166\/4\/article-p154.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.akjournals.com\/downloadpdf\/journals\/650\/166\/4\/article-p154.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/www.akjournals.com\/downloadpdf\/journals\/650\/166\/4\/article-p154.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T08:51:22Z","timestamp":1785487882000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.akjournals.com\/view\/journals\/650\/166\/4\/article-p154.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,26]]},"references-count":11,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.1556\/650.2025.33204","relation":{},"ISSN":["0030-6002","1788-6120"],"issn-type":[{"value":"0030-6002","type":"print"},{"value":"1788-6120","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,26]]}}}