{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T11:58:53Z","timestamp":1785499133462,"version":"3.56.0"},"reference-count":34,"publisher":"Akademiai Kiado Zrt.","issue":"6","license":[{"start":{"date-parts":[[2025,2,9]],"date-time":"2025-02-09T00:00:00Z","timestamp":1739059200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.akjournals.com"],"crossmark-restriction":true},"short-container-title":["OH"],"published-print":{"date-parts":[[2025,2,9]]},"abstract":"\n A hyperinsulinaemi\u00e1s hypoglykaemi\u00e1s t\u00fcnetegy\u00fcttes f\u0151 oka a pancreas neuroendokrin\n daganata, az insulinoma. A neh\u00e9zs\u00e9get a diagn\u00f3zis fel\u00e1ll\u00edt\u00e1s\u00e1n t\u00fal a tumor\n pontos lokaliz\u00e1ci\u00f3ja adja, mely els\u0151dleges a kurat\u00edv m\u0171t\u00e9t elv\u00e9gz\u00e9s\u00e9hez. 36 \u00e9ves\n n\u0151beteg\u00fcnk eset\u00e9ben zavarts\u00e1g, eszm\u00e9letveszt\u00e9ssel j\u00e1r\u00f3 rosszull\u00e9tek h\u00e1tter\u00e9ben\n igazol\u00f3dott hypoglykaemi\u00e1t okoz\u00f3 endog\u00e9n hyperinsulinaemia. Az MRI felvetette a\n pancreas farki r\u00e9sz\u00e9n 5 mm-es elt\u00e9r\u00e9s jelenl\u00e9t\u00e9t, mely ezt k\u00f6vet\u0151en sem a hasi\n CT-vizsg\u00e1laton, sem az insulinoma diagn\u00f3zis\u00e1ban nagy jelent\u0151s\u00e9ggel b\u00edr\u00f3\n endoszk\u00f3pos ultrahangvizsg\u00e1laton nem \u00e1br\u00e1zol\u00f3dott. Szint\u00e9n nem igazol\u00f3dott\n szomatosztatinreceptor-pozitivit\u00e1s a hasny\u00e1lmirigy ter\u00fclet\u00e9n az elv\u00e9gzett\n szomatosztatinreceptor-szcintigr\u00e1fia sor\u00e1n. A\n 68<\/jats:sup>\n Ga-exendin-PET\/CT\n ugyanakkor az MRI-n le\u00edrt laesi\u00f3nak megfelel\u0151 d\u00fasul\u00e1st jelzett a pancreas farki\n r\u00e9gi\u00f3j\u00e1ban. A vizsg\u00e1lat eredm\u00e9nye alapj\u00e1n distalis pancreasresectio t\u00f6rt\u00e9nt,\n melyet k\u00f6vet\u0151en a beteg hypoglykaemi\u00e1s rosszull\u00e9tei megsz\u0171ntek, \u00e9s a sz\u00f6vettani\n vizsg\u00e1lat a diagn\u00f3zist meger\u0151s\u00edtette. A hagyom\u00e1nyos k\u00e9palkot\u00f3 diagnosztikai\n m\u00f3dszerek gyakran nem informat\u00edvak az insulinoma lokaliz\u00e1l\u00e1s\u00e1ban, els\u0151sorban a\n kis m\u00e9ret\u0171, hipovaszkulariz\u00e1lt laesi\u00f3k eset\u00e9ben. A neuroendokrin daganatokn\u00e1l\n sz\u00e9lesk\u00f6r\u0171en alkalmazott szomatosztatin-receptor kimutat\u00e1s\u00e1t c\u00e9lz\u00f3 k\u00e9palkot\u00f3\n vizsg\u00e1latok az insulinom\u00e1k eset\u00e9ben negat\u00edv eredm\u00e9nyt adhatnak az alacsony\n szomatosztatinreceptor-expresszi\u00f3 miatt. Eset\u00fcnkben a leg\u00fajabb funkcion\u00e1lis\n k\u00e9palkot\u00f3 m\u00f3dszert, a\n 68<\/jats:sup>\n Ga-exendin-PET\/CT-t hat\u00e9konyan alkalmaztuk,\n mely specifikusan k\u00e9pes kimutatni m\u00e9g a kis m\u00e9ret\u0171 insulinom\u00e1kat is. Orv Hetil.\n 2025; 166(6): 228\u2013233.\n <\/jats:p>","DOI":"10.1556\/650.2025.33227","type":"journal-article","created":{"date-parts":[[2025,2,10]],"date-time":"2025-02-10T06:55:10Z","timestamp":1739170510000},"page":"228-233","update-policy":"https:\/\/doi.org\/10.1556\/policypage.crossmark.crossref.2","source":"Crossref","is-referenced-by-count":1,"title":["Kis m\u00e9ret\u0171 insulinoma lokaliz\u00e1l\u00e1sa 68Ga-exendin-PET"],"prefix":"10.1556","volume":"166","author":[{"given":"N\u00f3ra","family":"Garam","sequence":"first","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Belgy\u00f3gy\u00e1szati \u00e9s Onkol\u00f3giai Klinika Budapest, Kor\u00e1nyi S. u. 2\/a, 1083 Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikolette","family":"Sz\u00fccs","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Belgy\u00f3gy\u00e1szati \u00e9s Onkol\u00f3giai Klinika Budapest, Kor\u00e1nyi S. u. 2\/a, 1083 Magyarorsz\u00e1g"},{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Endokrinol\u00f3giai Tansz\u00e9k Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ildik\u00f3 T\u00fcnde","family":"B\u00e1lint","sequence":"additional","affiliation":[{"name":"Szabolcs-Szatm\u00e1r-Bereg V\u00e1rmegyei Oktat\u00f3k\u00f3rh\u00e1z, Ny\u00edregyh\u00e1zi J\u00f3sa Andr\u00e1s Tagk\u00f3rh\u00e1z, B\u0151rgy\u00f3gy\u00e1szati Oszt\u00e1ly \u00e9s Nemibeteg Gondoz\u00f3 Ny\u00edregyh\u00e1za Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gergely","family":"Huszty","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Seb\u00e9szeti, Transzplant\u00e1ci\u00f3s \u00e9s Gasztroenterol\u00f3giai Klinika Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e1s","family":"Budai","sequence":"additional","affiliation":[{"name":"Semmelweis Egyetem, \u00c1ltal\u00e1nos Orvostudom\u00e1nyi Kar, Patol\u00f3giai, Igazs\u00e1g\u00fcgyi \u00e9s Biztos\u00edt\u00e1si Orvostani Int\u00e9zet Budapest Magyarorsz\u00e1g"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatrix","family":"Kerecsen","sequence":"additional","affiliation":[{"name":"Huniko Kft. 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